Posted by Santiago Carmona on 2009-03-25 14:48:30
This query-set consist of 8 (sub)queries that look for genes in the T.cruzi genome having different desirable properties
such as absence in human, enzyme activity, ortholog gene(s) in T. brucei, essentiality evidence in any species (that could
be further refined asking for orthologs to essential genes in a particular model specie), significant druggability evidence
inferred from orthology, single-copy number (1 or 2 copies because of the pseudodiploid nature of the T.cruzi genome), availability of
structural models (PDB or Modbase) and assayablity; plus a composite query or ranked list which comes from the weighted UNION of the others.
You can import this queries to your session, redo the score strategy of the ranked list, or build a new one combining this queries with others.