Reweightable Pfal rankings based on 19 criteria

Posted by Greg Crowther on 2009-03-25 23:27:21

WARNING: This list was made prior to the version 4 release of TDR Targets (Aug, 2010). Some queries included in this list may not work properly. Most likely reasons for this are changes in parameters, and/or data updates. If you experience any problem, please try re-running each search from the search page.

List description

This is an update to a previously published multi-query ranking. The criteria used are the same, but performing these queries in the new version 3 of the database allows other users to easily reweight the queries.

Click on the links below to browse the contents of each query. You can also use the checkboxes to select queries you would like to import into your history.
Import ranked queries into your history to redo the scoring strategy
  • Pfal rankings for 19 criteria -- reweightable! (5589 records), 3
    • Score for genes in query #316 (Pfal early schizont 60-80): 4
    • Score for genes in query #302 (Pfal structural models): 30
    • Score for genes in query #295 (Pfal early trophozoite 80-100): 8
    • Score for genes in query #298 (Pfal late schizont 80-100): 8
    • Score for genes in query #293 (Pfal late schizont 60-80): 4
    • Score for genes in query #308 (Pfal early trophozoite 60-80): 4
    • Score for genes in query #304 (Pfal late trophozoite 60-80): 4
    • Score for genes in query #312 (Pfal merozoite 60-80): 4
    • Score for genes in query #306 (Pfal late ring 80-100): 8
    • Score for genes in query #299 (Pfal essential in at least one organism): 40
    • Score for genes in query #292 (Pfal merozoite 80-100): 8
    • Score for genes in query #294 (Pfal early schizont 80-100): 8
    • Score for genes in query #314 (Pfal late ring 60-80): 4
    • Score for genes in query #310 (Pfal late trophozoite 80-100): 8
    • Score for genes in query #303 (Pfal PDB structures): 50
    • Score for genes in query #313 (Pfal less than 100 kDa): 20
    • Score for genes in query #309 (Pfal no TM domains): 20
    • Score for genes in query #311 (Pfal druggability > 0.6): 35
    • Score for genes in query #291 (Pfal assayable): 30
    • Score for genes in query #300 (Pfal publications): 35
    • Score for genes in query #315 (Pfal compound desirability > 0.3): 35
    • Score for genes in query #305 (Pfal not in humans): 25
    • Score for genes in query #296 (Pfal early ring 60-80): 4
    • Score for genes in query #307 (Pfal genetic validation): 50
    • Score for genes in query #297 (Pfal early ring 80-100): 8
    • Score for genes in query #301 (Pfal enzymes): 100