TB weighted drug targets

Posted by Wes Van Voorhis on 2007-07-12 08:18:50

WARNING: This list was made prior to the version 4 release of TDR Targets (Aug, 2010). Some queries included in this list may not work properly. Most likely reasons for this are changes in parameters, and/or data updates. If you experience any problem, please try re-running each search from the search page.

List description

TB prioritized targets

Click on the links below to browse the contents of each query. You can also use the checkboxes to select queries you would like to import into your history.
Import ranked queries into your history to redo the scoring strategy
  • Wes VV TB Prioritized Targets: Structure, Enzyme, <600AA, essential, curated, not in human (4039 records), 3
    • Score for genes in query #61 (TB E coli essentials): 20
    • Score for genes in query #48 (TB curated): 50
    • Score for genes in query #63 (TB not in human): 10
    • Score for genes in query #52 (TB enzymes (any EC #)): 35
    • Score for genes in query #60 (TB known essentials): 35
    • Score for genes in query #59 (TB with Modeled structures): 20
    • Score for genes in query #54 (TB < 600 AA): 25
    • Score for genes in query #62 (TB essential in any species): 10
    • Score for genes in query #58 (TB w/ solved structures): 30