Target list

Search results for query: T. cruzi ranked list of targets

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #24 (significant druggability): 30
  • Score for genes in query #28 (strucural model available): 15
  • Score for genes in query #25 (essentiality evidence in any specie): 20
  • Score for genes in query #29 (assayable): 15
  • Score for genes in query #26 (ortholog in T. brucei): 20
  • Score for genes in query #22 (enzyme): 30
  • Score for genes in query #23 (not in human): 40
  • Score for genes in query #27 (single copy gene): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

18619 records found | Showing page 745 of 745 (records 18601-18619) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
T. cruzi   TcCLB.509399.150   OG5_134831   hypothetical protein, conserved 20
T. cruzi   TcCLB.510057.4   OG5_127605   EF-hand domain pair, putative 20
T. cruzi   TcCLB.509733.190   OG5_128960   Protein of unknown function (DUF778), putative 20
T. cruzi   TcCLB.505941.30   OG5_128411   ABC1 family, putative 20
T. cruzi   TcCLB.506297.340   OG5_126850   hypothetical protein, conserved 20
T. cruzi   TcCLB.508777.80   OG5_127013   Der1-like family, putative 20
T. cruzi   TcCLB.510043.29   OG5_130672   dolichol phosphate-mannose biosynthesis regulatory protein (DPM2), putative 20
T. cruzi   TcCLB.507997.60   OG5_128864   Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putat ... 20
T. cruzi   TcCLB.503809.90   OG5_128109   glycerol uptake protein, putative 20
T. cruzi   TcCLB.509437.80   OG5_165160   hypothetical protein, conserved 20
T. cruzi   TcCLB.508505.40   OG5_130326   Right handed beta helix region/Periplasmic copper-binding protein (NosD), putati ... 20
T. cruzi   TcCLB.509669.70   OG5_127047   hypothetical protein, conserved 20
T. cruzi   TcCLB.504089.50   OG5_129136   Flagellar radial spoke protein 4/6 20
T. cruzi   TcCLB.508821.40   OG5_128445   hypothetical protein, conserved 15
T. cruzi   TcCLB.508065.60   OG5_132011   hypothetical protein, conserved 15
T. cruzi   TcCLB.508739.30   OG5_174272   hypothetical protein 15
T. cruzi   TcCLB.506163.50   OG5_128445   hypothetical protein, conserved 15
T. cruzi   TcCLB.509707.25   OG5_132011   hypothetical protein, conserved 15
T. cruzi   TcCLB.510719.80   OG5_164200   hypothetical protein, conserved 15