Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
471 records found | Showing page 1 of 19 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0012 | OG5_171691 | Probable conserved membrane protein |
| M. tuberculosis | Rv0046c | OG5_139953 | myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ... |
| M. tuberculosis | Rv0047c | OG5_178684 | Conserved protein |
| M. tuberculosis | Rv0064 | OG5_152620 | Probable conserved transmembrane protein |
| M. tuberculosis | Rv0066c | OG5_126691 | Probable isocitrate dehydrogenase [NADP] Icd2 (oxalosuccinate decarboxylase) (ID ... |
| M. tuberculosis | Rv0074 | OG5_133329 | Conserved protein |
| M. tuberculosis | Rv0080 | No group | Conserved hypothetical protein |
| M. tuberculosis | Rv0082 | OG5_143851 | Probable oxidoreductase |
| M. tuberculosis | Rv0084 | OG5_140388 | Possible formate hydrogenlyase HycD (FHL) |
| M. tuberculosis | Rv0086 | OG5_134238 | Possible hydrogenase HycQ |
| M. tuberculosis | Rv0094c | OG5_151920 | Conserved hypothetical protein |
| M. tuberculosis | Rv0116c | OG5_237840 | Probable L,D-transpeptidase LdtA |
| M. tuberculosis | Rv0129c | OG5_237839 | Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transfe ... |
| M. tuberculosis | Rv0131c | OG5_239106 | Probable acyl-CoA dehydrogenase FadE1 |
| M. tuberculosis | Rv0137c | OG5_126847 | Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide ... |
| M. tuberculosis | Rv0140 | OG5_144561 | Conserved protein |
| M. tuberculosis | Rv0141c | No group | Unknown protein |
| M. tuberculosis | Rv0147 | OG5_127094 | Probable aldehyde dehydrogenase (NAD+) dependent |
| M. tuberculosis | Rv0179c | No group | Possible lipoprotein LprO |
| M. tuberculosis | Rv0188 | No group | Probable conserved transmembrane protein |
| M. tuberculosis | Rv0190 | OG5_136234 | Conserved protein |
| M. tuberculosis | Rv0191 | OG5_134076 | Probable conserved integral membrane protein |
| M. tuberculosis | Rv0195 | No group | Possible two component transcriptional regulatory protein (probably LuxR-family) |
| M. tuberculosis | Rv0196 | OG5_191363 | Possible transcriptional regulatory protein |
| M. tuberculosis | Rv0197 | OG5_175709 | Possible oxidoreductase |