Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
783 records found | Showing page 1 of 32 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| M. tuberculosis | Rv0973c | No group | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) Ac ... |
| M. tuberculosis | Rv3280 | OG5_130273 | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:ca ... |
| M. tuberculosis | Rv1916 | OG5_129572 | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) |
| M. tuberculosis | Rv2523c | OG5_130884 | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pant ... |
| M. tuberculosis | Rv3391 | OG5_130166 | Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 |
| M. tuberculosis | Rv1862 | OG5_126661 | Probable alcohol dehydrogenase AdhA |
| M. tuberculosis | Rv3045 | OG5_126661 | Probable NADP-dependent alcohol dehydrogenase AdhC |
| M. tuberculosis | Rv3086 | OG5_127257 | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) |
| M. tuberculosis | Rv2471 | OG5_126827 | Probable alpha-glucosidase AglA (maltase) (glucoinvertase) (glucosidosucrase) (m ... |
| M. tuberculosis | Rv3107c | OG5_130256 | Possible alkyldihydroxyacetonephosphate synthase AgpS (alkyl-DHAP synthase) (alk ... |
| M. tuberculosis | Rv2428 | OG5_126593 | Alkyl hydroperoxide reductase C protein AhpC (alkyl hydroperoxidase C) |
| M. tuberculosis | Rv2429 | OG5_165107 | Alkyl hydroperoxide reductase D protein AhpD (alkyl hydroperoxidase D) |
| M. tuberculosis | Rv2780 | OG5_127241 | Secreted L-alanine dehydrogenase Ald (40 kDa antigen) (TB43) |
| M. tuberculosis | Rv0768 | OG5_127004 | Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+ ... |
| M. tuberculosis | Rv3252c | OG5_156889 | Probable transmembrane alkane 1-monooxygenase AlkB (alkane 1-hydroxylase) (lauri ... |
| M. tuberculosis | Rv3305c | OG5_127543 | Possible N-acyl-L-amino acid amidohydrolase AmiA1 (N-acyl-L-amino acid aminohydr ... |
| M. tuberculosis | Rv3306c | OG5_129913 | Probable amidohydrolase AmiB1 (aminohydrolase) |
| M. tuberculosis | Rv2888c | OG5_141344 | Probable amidase AmiC (aminohydrolase) |
| M. tuberculosis | Rv3375 | OG5_174922 | Probable amidase AmiD (acylamidase) (acylase) |
| M. tuberculosis | Rv1538c | OG5_127035 | Probable L-aparaginase AnsA |
| M. tuberculosis | Rv1654 | OG5_130618 | Probable acetylglutamate kinase ArgB |
| M. tuberculosis | Rv1655 | OG5_126982 | Probable acetylornithine aminotransferase ArgD |
| M. tuberculosis | Rv1658 | OG5_127707 | Probable argininosuccinate synthase ArgG |
| M. tuberculosis | Rv2538c | OG5_127183 | 3-dehydroquinate synthase AroB |
| M. tuberculosis | Rv2537c | OG5_132746 | 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) |