Target list

Search results for query: Ranked list of the genes in this set

  • Score for genes in query #1 (Plasmodium enzymes): 20
  • Score for genes in query #3 (3: Plasmodium genes essential in Mycobacterium): 30
  • Score for genes in query #2 (Plasmodium genes absent in mammals): 50
  • Score for genes in query #4 (Plasmodium genes essential in E. coli): 30

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.


3515 records found | Showing page 1 of 141 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_1022800   OG5_130276   4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 130
P. falciparum   PF3D7_1323000   OG5_130367   beta-hydroxyacyl-ACP dehydratase 130
P. falciparum   PF3D7_1327600   OG5_131883   nicotinamide/nicotinic acid mononucleotide adenylyltransferase 130
P. falciparum   PF3D7_1467300   OG5_130462   1-deoxy-D-xylulose 5-phosphate reductoisomerase 130
P. falciparum   PF3D7_0104400   OG5_130373   4-hydroxy-3-methylbut-2-enyl diphosphate reductase 130
P. falciparum   PF3D7_0209300   OG5_130616   2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 130
P. falciparum   PF3D7_0211400   OG5_129509   beta-ketoacyl-ACP synthase III 130
P. falciparum   PF3D7_0219500   OG5_128305   pseudouridine synthase, putative 130
P. falciparum   PF3D7_0420200   OG5_130884   holo-[acyl-carrier-protein] synthase, putative 130
P. falciparum   PF3D7_0503100   OG5_130885   4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, putative 130
P. falciparum   PF3D7_0615100   OG5_130466   enoyl-acyl carrier reductase 130
P. falciparum   PF3D7_1223300   OG5_129568   DNA gyrase subunit A 130
P. falciparum   PF3D7_1350700   OG5_130478   N6-adenine-specific methylase, putative 110
P. falciparum   PF3D7_1365100   OG5_149624   mitochondrial ribosomal protein S17 precursor, putative 110
P. falciparum   PF3D7_1033400   OG5_127435   haloacid dehalogenase-like hydrolase 110
P. falciparum   PF3D7_1469000   OG5_130791   translation initiation factor IF-1 110
P. falciparum   PF3D7_0206100   OG5_127283   cysteine desulfuration protein SufE 110
P. falciparum   PF3D7_0503000   OG5_130709   50S ribosomal protein L28, apicoplast, putative 110
P. falciparum   PF3D7_0613400   OG5_130467   apicoplast ribosomal protein L18 precursor, putative 110
P. falciparum   PF3D7_1226300   OG5_138778   haloacid dehalogenase-like hydrolase, putative 110
P. falciparum   PF3D7_0716600   OG5_128800   cysteine desulfurase 100
P. falciparum   PF3D7_0810800   OG5_128803   hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase 100
P. falciparum   PF3D7_1435300   OG5_126892   NAD(P)H-dependent glutamate synthase, putative 100
P. falciparum   PF3D7_0520500   OG5_128612   phosphomethylpyrimidine kinase, putative 100
P. falciparum   PF3D7_0623000   OG5_128304   chorismate synthase 100