Target list

Search results for query: Union of (#1, #2, #7, #8)

  • Score for genes in query #7 (Plasmodium falciparum genes with druggability index higher than 0.7): 40
  • Score for genes in query #8 (Plamodium falciparum genes with any essentiality ): 50
  • Score for genes in query #1 (Plasmodium falciparum enzymes with structure): 10
  • Score for genes in query #2 (Plasmodium falciparum genes present in parasites and yeast but absent in animals): 20

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

1481 records found | Showing page 1 of 60 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_0615100   OG5_130466   enoyl-acyl carrier reductase 120
P. falciparum   PF3D7_1223300   OG5_129568   DNA gyrase subunit A 120
P. falciparum   PF3D7_1005000   OG5_166421   methionine--tRNA ligase, putative 100
P. falciparum   PF3D7_1015800   OG5_145115   ribonucleoside-diphosphate reductase small chain, putative 100
P. falciparum   PF3D7_1017000   OG5_127429   DNA polymerase delta catalytic subunit 100
P. falciparum   PF3D7_1029600   OG5_127245   adenosine deaminase 100
P. falciparum   PF3D7_1034900   OG5_127468   methionine--tRNA ligase 100
P. falciparum   PF3D7_1128400   OG5_127590   geranylgeranyl pyrophosphate synthase, putative 100
P. falciparum   PF3D7_1134700   OG5_127929   DNA-directed RNA polymerase I subunit RPA2, putative 100
P. falciparum   PF3D7_1308200   OG5_126835   carbamoyl phosphate synthetase 100
P. falciparum   PF3D7_1311900   OG5_127237   V-type proton ATPase catalytic subunit A 100
P. falciparum   PF3D7_1332900   OG5_126684   isoleucine--tRNA ligase, putative 100
P. falciparum   PF3D7_1405600   OG5_126823   ribonucleoside-diphosphate reductase small chain, putative 100
P. falciparum   PF3D7_1412600   OG5_127351   deoxyhypusine synthase 100
P. falciparum   PF3D7_1433500   OG5_127113   DNA topoisomerase 2 100
P. falciparum   PF3D7_1461900   OG5_126723   valine--tRNA ligase, putative 100
S. mansoni   ATP6   OG5_128903   ATP synthase F0 subunit 6 100
P. falciparum   PF3D7_0110600   OG5_126948   phosphatidylinositol-4-phosphate 5-kinase 100
P. falciparum   PF3D7_0211700   OG5_130251   tyrosine kinase-like protein, putative 100
P. falciparum   PF3D7_0215700   OG5_126694   DNA-directed RNA polymerase II subunit RPB2, putative 100
P. falciparum   PF3D7_0217100   OG5_127165   ATP synthase F1, alpha subunit 100
P. falciparum   PF3D7_0312400   OG5_126888   glycogen synthase kinase 3 100
P. falciparum   PF3D7_0406100   OG5_127061   V-type proton ATPase subunit B 100
P. falciparum   PF3D7_0411900   OG5_128177   DNA polymerase alpha catalytic subunit A 100
P. falciparum   PF3D7_0417200   OG5_127385   bifunctional dihydrofolate reductase-thymidylate synthase 100

Showing page 1 (records 1-25) of 60