Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
3356 records found | Showing page 1 of 135 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
P. falciparum | PF3D7_0615100 | OG5_130466 | enoyl-acyl carrier reductase | 60 |
P. falciparum | PF3D7_1223300 | OG5_129568 | DNA gyrase subunit A | 60 |
P. falciparum | PF3D7_1239500 | OG5_128755 | DNA gyrase subunit B | 60 |
P. falciparum | PF3D7_1005000 | OG5_166421 | methionine--tRNA ligase, putative | 50 |
P. falciparum | PF3D7_1015800 | OG5_145115 | ribonucleoside-diphosphate reductase small chain, putative | 50 |
P. falciparum | PF3D7_1017000 | OG5_127429 | DNA polymerase delta catalytic subunit | 50 |
P. falciparum | PF3D7_1029600 | OG5_127245 | adenosine deaminase | 50 |
P. falciparum | PF3D7_1034900 | OG5_127468 | methionine--tRNA ligase | 50 |
P. falciparum | PF3D7_1128400 | OG5_127590 | geranylgeranyl pyrophosphate synthase, putative | 50 |
P. falciparum | PF3D7_1134700 | OG5_127929 | DNA-directed RNA polymerase I subunit RPA2, putative | 50 |
P. falciparum | PF3D7_1308200 | OG5_126835 | carbamoyl phosphate synthetase | 50 |
P. falciparum | PF3D7_1311900 | OG5_127237 | V-type proton ATPase catalytic subunit A | 50 |
P. falciparum | PF3D7_1332900 | OG5_126684 | isoleucine--tRNA ligase, putative | 50 |
P. falciparum | PF3D7_1405600 | OG5_126823 | ribonucleoside-diphosphate reductase small chain, putative | 50 |
P. falciparum | PF3D7_1412600 | OG5_127351 | deoxyhypusine synthase | 50 |
P. falciparum | PF3D7_1433500 | OG5_127113 | DNA topoisomerase 2 | 50 |
P. falciparum | PF3D7_1461900 | OG5_126723 | valine--tRNA ligase, putative | 50 |
S. mansoni | ATP6 | OG5_128903 | ATP synthase F0 subunit 6 | 50 |
P. falciparum | PF3D7_0110600 | OG5_126948 | phosphatidylinositol-4-phosphate 5-kinase | 50 |
P. falciparum | PF3D7_0211700 | OG5_130251 | tyrosine kinase-like protein, putative | 50 |
P. falciparum | PF3D7_0215700 | OG5_126694 | DNA-directed RNA polymerase II subunit RPB2, putative | 50 |
P. falciparum | PF3D7_0217100 | OG5_127165 | ATP synthase F1, alpha subunit | 50 |
P. falciparum | PF3D7_0312400 | OG5_126888 | glycogen synthase kinase 3 | 50 |
P. falciparum | PF3D7_0406100 | OG5_127061 | V-type proton ATPase subunit B | 50 |
P. falciparum | PF3D7_0411900 | OG5_128177 | DNA polymerase alpha catalytic subunit A | 50 |