Target list

Search results for query: Union of (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 19)

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  • Score for genes in query #3 (in mouse): -20
  • Score for genes in query #11 (3D model available): 2
  • Score for genes in query #10 (Sterility in C. elegans): 20
  • Score for genes in query #4 (in C. elegans): 10
  • Score for genes in query #8 (Larval/Adult Lethal/Arrest in C. elegans): 40
  • Score for genes in query #2 (in human): -40
  • Score for genes in query #7 (Growth Defect in C. elegans): 20
  • Score for genes in query #19 (druggable genes inferred by sequence simiarity): 30
  • Score for genes in query #5 (any essentiality evidence): 5
  • Score for genes in query #6 (Embryonic Lethal/Arrest in C. elegans): 30
  • Score for genes in query #13 (bibliographic reference): 2
  • Score for genes in query #9 (Morphology Defect in C. elegans): 20
  • Score for genes in query #12 (enzyme): 10

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

8930 records found | Showing page 1 of 358 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
B. malayi   Bm1_44415   OG5_192700   Neurotransmitter-gated ion-channel ligand binding domain containing protein 157
B. malayi   Bm1_30720   OG5_127549   KE2 family protein 157
B. malayi   Bm1_12850   OG5_127845   Rhodanese-like domain containing protein 147
B. malayi   Bm1_12860   OG5_127845   Rhodanese-like domain containing protein 147
B. malayi   Bm1_19440   OG5_134436   hypothetical protein 147
B. malayi   Bm1_27330   OG5_179002   hypothetical protein 145
B. malayi   Bm1_48810   OG5_179095   EF hand family protein 137
B. malayi   Bm1_43680   OG5_127998   T-complex protein 1, alpha subunit 137
B. malayi   Bm1_20490   OG5_131038   Nuclear hormone receptor family member nhr-49 137
B. malayi   Bm1_44370   OG5_192698   Vacuolar ATP synthase 16 kDa proteolipid subunit 1, putative 137
B. malayi   Bm1_48865   OG5_126846   Csnk2b protein 129
B. malayi   Bm1_35945   OG5_128520   Protein kinase domain containing protein 129
B. malayi   Bm1_51715   OG5_192849   hypothetical protein 127
B. malayi   Bm1_17365     No group RNA-directed RNA polymerase 1 127
B. malayi   Bm1_27860   OG5_130286   RNA dependent RNA polymerase family protein 127
B. malayi   Bm1_21530   OG5_163512   hypothetical protein 127
B. malayi   Bm1_46145   OG5_192733   mitochondria bc1 complex core subunit 1 127
B. malayi   Bm1_05435   OG5_186478   hypothetical protein 127
B. malayi   Bm1_41775   OG5_131239   UBA/TS-N domain containing protein 127
B. malayi   Bm1_50895   OG5_146745   cuticle collagen 1 precursor 127
B. malayi   Bm1_25540   OG5_178996   hypothetical protein 127
B. malayi   Bm1_25205   OG5_127407   leucyl-tRNA synthetase 127
B. malayi   Bm1_46445   OG5_126705   vacuolar proton pump 127
B. malayi   Bm1_11685   OG5_192116   Patched related family protein 4 127
B. malayi   Bm1_24805   OG5_127761   proteasome subunit beta type 3 127

Showing page 1 (records 1-25) of 358