Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
17 records found | Showing page 1 of 1 (records 1-17) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| P. falciparum | PF3D7_0417200 | OG5_127385 | bifunctional dihydrofolate reductase-thymidylate synthase |
| P. falciparum | PF3D7_0603300 | OG5_127289 | dihydroorotate dehydrogenase |
| P. falciparum | PF3D7_0623000 | OG5_128304 | chorismate synthase |
| P. falciparum | PF3D7_0629300 | OG5_128356 | phospholipase, putative |
| P. falciparum | PF3D7_0731500 | OG5_148188 | erythrocyte binding antigen-175 |
| P. falciparum | PF3D7_0810800 | OG5_128803 | hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase |
| P. falciparum | PF3D7_0916100 | OG5_141346 | thioredoxin 3 |
| P. falciparum | PF3D7_1012400 | OG5_127374 | hypoxanthine-guanine phosphoribosyltransferase |
| P. falciparum | PF3D7_1115700 | OG5_126607 | cysteine proteinase falcipain 2a |
| P. falciparum | PF3D7_1212800 | OG5_126893 | iron-sulfur subunit of succinate dehydrogenase |
| P. falciparum | PF3D7_1239500 | OG5_128755 | DNA gyrase subunit B |
| P. falciparum | PF3D7_1347200 | OG5_146508 | nucleoside transporter 1 |
| P. falciparum | PF3D7_1405600 | OG5_126823 | ribonucleoside-diphosphate reductase small chain, putative |
| P. falciparum | PF3D7_1414400 | OG5_126821 | serine/threonine protein phosphatase PP1 |
| P. falciparum | PF3D7_1439900 | OG5_127002 | triosephosphate isomerase |
| P. falciparum | PF3D7_1444800 | OG5_127143 | fructose-bisphosphate aldolase |
| P. falciparum | PF3D7_1458000 | OG5_141501 | cysteine proteinase falcipain 1 |