Target list

Search results for query: Mtb PDB structure

  • Structures: PDB
  • Species: mtu

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.


504 records found | Showing page 1 of 21 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
M. tuberculosis   Rv0002   OG5_132148   DNA polymerase III (beta chain) DnaN (DNA nucleotidyltransferase)
M. tuberculosis   Rv0005   OG5_128755   DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ...
M. tuberculosis   Rv0006   OG5_129568   DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ...
M. tuberculosis   Rv0009   OG5_128211   Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (r ...
M. tuberculosis   Rv0011c   OG5_237531   Probable conserved transmembrane protein
M. tuberculosis   Rv0014c   OG5_146588   Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B)
M. tuberculosis   Rv0015c   OG5_155711   Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A)
M. tuberculosis   Rv0016c   OG5_133524   Probable penicillin-binding protein PbpA
M. tuberculosis   Rv0033     No group Probable acyl carrier protein AcpA (ACP)
M. tuberculosis   Rv0040c   OG5_237533   Secreted proline rich protein Mtc28 (proline rich 28 kDa antigen)
M. tuberculosis   Rv0046c   OG5_139953   myo-inositol-1-phosphate synthase Ino1 (inositol 1-phosphate synthetase) (D-gluc ...
M. tuberculosis   Rv0058   OG5_131890   Probable replicative DNA helicase DnaB
M. tuberculosis   Rv0060   OG5_133608   Conserved hypothetical protein
M. tuberculosis   Rv0062   OG5_137267   Possible cellulase CelA1 (endoglucanase) (endo-1,4-beta-glucanase) (FI-cmcase) ( ...
M. tuberculosis   Rv0066c   OG5_126691   Probable isocitrate dehydrogenase [NADP] Icd2 (oxalosuccinate decarboxylase) (ID ...
M. tuberculosis   Rv0070c   OG5_126679   Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2)
M. tuberculosis   Rv0096   OG5_237742   PPE family protein PPE1
M. tuberculosis   Rv0098   OG5_237743   Probable fatty acyl CoA thioesterase type III FcoT
M. tuberculosis   Rv0099   OG5_163246   Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-Co ...
M. tuberculosis   Rv0116c   OG5_237840   Probable L,D-transpeptidase LdtA
M. tuberculosis   Rv0125   OG5_171368   Probable serine protease PepA (serine proteinase) (MTB32A)
M. tuberculosis   Rv0126   OG5_126827   Trehalose synthase TreS
M. tuberculosis   Rv0127   OG5_239105   Maltokinase Mak
M. tuberculosis   Rv0129c   OG5_237839   Secreted antigen 85-C FbpC (85C) (antigen 85 complex C) (AG58C) (mycolyl transfe ...
M. tuberculosis   Rv0130   OG5_142681   Probable 3-hydroxyl-thioester dehydratase