Target list

Search results for query: Mtb any essentiality evidence

  • Essential: Any
  • Species: mtu

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.


1043 records found | Showing page 1 of 42 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
M. tuberculosis   Rv0001   OG5_132291   Chromosomal replication initiator protein DnaA
M. tuberculosis   Rv0002   OG5_132148   DNA polymerase III (beta chain) DnaN (DNA nucleotidyltransferase)
M. tuberculosis   Rv0005   OG5_128755   DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ...
M. tuberculosis   Rv0006   OG5_129568   DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisome ...
M. tuberculosis   Rv0009   OG5_128211   Probable iron-regulated peptidyl-prolyl cis-trans isomerase A PpiA (PPIase A) (r ...
M. tuberculosis   Rv0014c   OG5_146588   Transmembrane serine/threonine-protein kinase B PknB (protein kinase B) (STPK B)
M. tuberculosis   Rv0015c   OG5_155711   Transmembrane serine/threonine-protein kinase A PknA (protein kinase A) (STPK A)
M. tuberculosis   Rv0016c   OG5_133524   Probable penicillin-binding protein PbpA
M. tuberculosis   Rv0032   OG5_126783   Possible 8-amino-7-oxononanoate synthase BioF2 (AONS) (8-amino-7-ketopelargonate ...
M. tuberculosis   Rv0038   OG5_131289   Conserved protein
M. tuberculosis   Rv0041   OG5_127675   Probable leucyl-tRNA synthetase LeuS (leucine--tRNA ligase) (LEURS)
M. tuberculosis   Rv0045c   OG5_128173   Possible hydrolase
M. tuberculosis   Rv0053   OG5_131749   30S ribosomal protein S6 RpsF
M. tuberculosis   Rv0054   OG5_127389   Single-strand binding protein Ssb (helix-destabilizing protein)
M. tuberculosis   Rv0055   OG5_128626   30S ribosomal protein S18-1 RpsR1
M. tuberculosis   Rv0058   OG5_131890   Probable replicative DNA helicase DnaB
M. tuberculosis   Rv0060   OG5_133608   Conserved hypothetical protein
M. tuberculosis   Rv0066c   OG5_126691   Probable isocitrate dehydrogenase [NADP] Icd2 (oxalosuccinate decarboxylase) (ID ...
M. tuberculosis   Rv0068   OG5_126621   Probable oxidoreductase
M. tuberculosis   Rv0070c   OG5_126679   Serine hydroxymethyltransferase GlyA2 (serine methylase 2) (SHMT 2)
M. tuberculosis   Rv0073   OG5_126906   Probable glutamine-transport ATP-binding protein ABC transporter
M. tuberculosis   Rv0085   OG5_147565   Possible hydrogenase HycP
M. tuberculosis   Rv0086   OG5_134238   Possible hydrogenase HycQ
M. tuberculosis   Rv0092   OG5_126855   Cation transporter P-type ATPase a CtpA
M. tuberculosis   Rv0102   OG5_156768   Probable conserved integral membrane protein