Target list

Search results for query: Orthologs of D. melanogaster genes with mutant phenotype lethal

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.


2101 records found | Showing page 1 of 85 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
S. mansoni   Smp_063300   OG5_127134   60S ribosomal protein L36e
S. mansoni   Smp_024390.1   OG5_129793   microsomal signal peptidase 25 kD subunit
S. mansoni   Smp_141410   OG5_208183   cell adhesion molecule
S. mansoni   Smp_051410   OG5_142427   septate junction protein
S. mansoni   Smp_135480   OG5_129672   tetratricopeptide repeat protein 10 tpr10
S. mansoni   Smp_102690.2   OG5_171615   eukaryotic translation initiation factor 2c
S. mansoni   Smp_085240.2   OG5_130252   lipid phosphate phosphatase-related
S. mansoni   Smp_155270   OG5_190385   hydroxymethylglutaryl-CoA synthase
S. mansoni   Smp_179800   OG5_127124   serine/threonine protein kinase
S. mansoni   Smp_147430   OG5_127034   glutamate receptor kainate
S. mansoni   Smp_004810.3   OG5_126821   protein phosphatase type 1
S. mansoni   Smp_170930   OG5_128723   intermediate filament proteins
S. mansoni   Smp_044550.1   OG5_129242   far upstream (fuse) binding protein
S. mansoni   Smp_180070   OG5_133654   gem-associated protein 5 (gemin5)
S. mansoni   Smp_152550   OG5_210724   phosphatidylinositol-binding clathrin assembly protein
S. mansoni   Smp_044010.2   OG5_127228   tropomyosin
S. mansoni   Smp_027920   OG5_126605   tubulin subunit alpha
S. mansoni   Smp_138050.1   OG5_127719   polypyrimidine tract binding protein
S. mansoni   Smp_140900.1   OG5_127054   hypothetical protein
S. mansoni   Smp_005910   OG5_128071   protein tyrosine phosphatase prl
S. mansoni   Smp_142650.2   OG5_159804   hypothetical protein
S. mansoni   Smp_037860     No group talin
S. mansoni   Smp_022990   OG5_127746   voltage-dependent anion-selective channel
S. mansoni   Smp_078050   OG5_132010   hypothetical protein
S. mansoni   Smp_133990.1   OG5_128953   topbp1