Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
360 records found | Showing page 1 of 15 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product |
---|---|---|---|
T. brucei | Tb05.5K5.30 | OG5_138502 | serine/threonine protein phosphatase, putative |
T. brucei | Tb09.v4.0009 | OG5_126617 | receptor-type adenylate cyclase, putative |
T. brucei | Tb11.02.5420b | OG5_127162 | NADPH-cytochrome p450 reductase, putative |
T. brucei | Tb11.v5.0162 | OG5_127834 | proteasome beta 6 subunit |
T. brucei | Tb11.v5.0196 | OG5_127884 | Proteasome subunit A N-terminal signature/Proteasome subunit, putative |
T. brucei | Tb11.v5.0210 | OG5_168255 | adenosine transporter, putative |
T. brucei | Tb11.v5.0281 | OG5_126617 | receptor-type adenylate cyclase GRESAG 4, putative |
T. brucei | Tb11.v5.0409 | OG5_127281 | guanine deaminase, putative |
T. brucei | Tb11.v5.0429 | OG5_126617 | receptor-type adenylate cyclase GRESAG 4, putative |
T. brucei | Tb11.v5.0456 | OG5_126617 | receptor-type adenylate cyclase GRESAG 4, putative |
T. brucei | Tb11.v5.0474 | OG5_154473 | protein kinase, putative |
T. brucei | Tb11.v5.0531 | OG5_127143 | fructose-bisphosphate aldolase, glycosomal, putative |
T. brucei | Tb11.v5.0668 | OG5_126843 | protein disulfide isomerase |
T. brucei | Tb11.v5.0671 | OG5_126748 | protein kinase A catalytic subunit, putative |
T. brucei | Tb11.v5.0718 | OG5_126888 | protein kinase, putative |
T. brucei | Tb11.v5.0998 | OG5_126721 | methionine aminopeptidase, putative |
T. brucei | Tb427.10.5940 | No group | (OTHER) NEK family, HsNEK1-like |
T. brucei | Tb427tmp.03.0935 | OG5_150846 | DNA-directed RNA polymerase subunit, putative |
T. brucei | Tb427tmp.03.0990 | OG5_126617 | expression site-associated gene 4 (ESAG4) protein, putative |
T. brucei | Tb427tmp.211.3570 | OG5_126746 | glycerol kinase, glycosomal |
T. brucei | Tb927.1.2100 | OG5_135138 | Calpain-like protein 1.1 |
T. brucei | Tb927.1.2110 | OG5_146880 | Calpain-like protein 1.2 |
T. brucei | Tb927.1.2740 | OG5_162210 | lipase-like protein, putative |
T. brucei | Tb927.1.3000 | OG5_127543 | amidohydrolase, putative |
T. brucei | Tb927.1.3120 | OG5_147248 | Peptidase C50 separase, putative |