Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
12 records found | Showing page 1 of 1 (records 1-12) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product | Weight |
|---|---|---|---|---|
| T. brucei | Tb927.6.4280 | OG5_126628 | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 40 |
| T. brucei | Tb927.6.4300 | OG5_126628 | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 40 |
| T. brucei | Tb927.10.6880 | OG5_126628 | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 40 |
| T. brucei | Tb927.1.1130 | OG5_145937 | glycerol-3-phosphate dehydrogenase (FAD-dependent), putative | 30 |
| T. brucei | Tb927.5.3580 | OG5_129378 | phosphoglycerate mutase protein, putative | 30 |
| T. brucei | Tb927.8.3530 | OG5_126704 | glycerol-3-phosphate dehydrogenase [NAD+], glycosomal | 30 |
| T. brucei | Tb927.11.7380 | OG5_127215 | glycerol-3-phosphate dehydrogenase (FAD-dependent), mitochondrial | 30 |
| T. brucei | Tb927.1.720 | OG5_161855 | phosphoglycerate kinase | 10 |
| T. brucei | Tb927.10.2890 | OG5_126698 | enolase | 10 |
| T. brucei | Tb927.1.700 | OG5_126776 | phosphoglycerate kinase | 10 |
| T. brucei | Tb927.1.710 | OG5_126776 | phosphoglycerate kinase | 10 |
| T. brucei | Tb11.v5.0531 | OG5_127143 | fructose-bisphosphate aldolase, glycosomal, putative | 10 |