Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
211 records found | Showing page 1 of 9 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| B. malayi | Bm1_00150 | No group | hexokinase type II |
| B. malayi | Bm1_00270 | OG5_128628 | ImpB/MucB/SamB family protein |
| B. malayi | Bm1_00555 | No group | astacin protease protein 30 |
| B. malayi | Bm1_01930 | OG5_126758 | 6-phosphofructokinase |
| B. malayi | Bm1_02445 | OG5_128367 | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 |
| B. malayi | Bm1_02530 | OG5_129590 | hypothetical protein |
| B. malayi | Bm1_03120 | OG5_127024 | serine/threonine kinase 12 |
| B. malayi | Bm1_03335 | OG5_131830 | protein kinase C3,putative |
| B. malayi | Bm1_03415 | OG5_171256 | protein-tyrosine phosphatase Lar-like precursor, putative |
| B. malayi | Bm1_03885 | OG5_127111 | Peptidase family C54 containing protein |
| B. malayi | Bm1_03920 | OG5_133034 | Cytochrome c oxidase subunit IV family protein |
| B. malayi | Bm1_04060 | OG5_127410 | Malate dehydrogenase, cytoplasmic |
| B. malayi | Bm1_04145 | OG5_191988 | metalloprotease 1 precursor |
| B. malayi | Bm1_04640 | OG5_128622 | Plasmid Maintenance Protein containing protein |
| B. malayi | Bm1_04665 | OG5_129051 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase |
| B. malayi | Bm1_04825 | OG5_126785 | glutathione reductase |
| B. malayi | Bm1_05660 | OG5_131130 | signal transduction protein CBL-B |
| B. malayi | Bm1_05720 | OG5_129189 | Protein kinase domain containing protein |
| B. malayi | Bm1_06755 | OG5_126929 | endochitinase |
| B. malayi | Bm1_06910 | OG5_127429 | DNA polymerase delta catalytic subunit |
| B. malayi | Bm1_07340 | OG5_192047 | zinc metalloproteinase toh-2 precursor |
| B. malayi | Bm1_07565 | OG5_129071 | geranylgeranyl pyrophosphate synthetase |
| B. malayi | Bm1_07900 | OG5_128752 | hypothetical protein |
| B. malayi | Bm1_08135 | OG5_132836 | cell division protein kinase 10 |
| B. malayi | Bm1_08705 | OG5_127113 | DNA topoisomerase II, alpha isozyme |