Target list

Search results for query: Union of (#1, #2, #3, #4, #5, #6, #9)

  • Score for genes in query #4 (essential somewhere): 30
  • Score for genes in query #3 (not in mammals): 50
  • Score for genes in query #6 (literature): 30
  • Score for genes in query #9 (plasmodium protease): 100
  • Score for genes in query #2 (has structure): 50
  • Score for genes in query #1 (plasmodium peptidase): 100
  • Score for genes in query #5 (druggability >0.3): 50

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4737 records found | Showing page 1 of 190 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_0804400   OG5_156787   methionine aminopeptidase 1c, putative 280
P. falciparum   PF3D7_1033800   OG5_145118   plasmepsin VII 280
P. falciparum   PF3D7_1015300   OG5_126721   methionine aminopeptidase 1b, putative 260
P. falciparum   PF3D7_1434600   OG5_127231   methionine aminopeptidase 2 260
P. falciparum   PF3D7_0527300   OG5_126721   methionine aminopeptidase 1a, putative 260
P. falciparum   PF3D7_1406600   OG5_133657   ATP-dependent Clp protease regulatory subunit ClpC, putative 250
P. falciparum   PF3D7_1440200   OG5_135834   stromal-processing peptidase, putative 250
P. falciparum   PF3D7_1311800   OG5_130542   M1-family alanyl aminopeptidase 230
P. falciparum   PF3D7_1136900   OG5_149511   subtilisin-like protease 2 230
P. falciparum   PF3D7_1323500   OG5_132039   plasmepsin V 230
P. falciparum   PF3D7_1430200   OG5_133546   plasmepsin IX 230
P. falciparum   PF3D7_1446200   OG5_127293   M17 leucyl aminopeptidase 230
P. falciparum   PF3D7_0307400   OG5_127187   ATP-dependent Clp protease proteolytic subunit 230
P. falciparum   PF3D7_0311700   OG5_126885   plasmepsin VI 230
P. falciparum   PF3D7_0507500   OG5_138369   subtilisin-like protease 1 230
P. falciparum   PF3D7_0902800   OG5_132467   serine repeat antigen 9 230
P. falciparum   PF3D7_0932300   OG5_128020   M18 aspartyl aminopeptidase 230
P. falciparum   PF3D7_0810800   OG5_128803   hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase 210
P. falciparum   PF3D7_0211400   OG5_129509   beta-ketoacyl-ACP synthase III 210
P. falciparum   PF3D7_0615100   OG5_130466   enoyl-acyl carrier reductase 210
P. falciparum   PF3D7_1223300   OG5_129568   DNA gyrase subunit A 210
P. falciparum   PF3D7_1239500   OG5_128755   DNA gyrase subunit B 210
P. falciparum   PF3D7_0807700   OG5_133046   serine protease DegP 200
P. falciparum   PF3D7_1401300   OG5_140207   epoxide hydrolase 2 200
P. falciparum   PF3D7_1436800   OG5_134854   ATP-dependent Clp protease proteolytic subunit 200