Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
2253 records found | Showing page 1 of 91 (records 1-25) | Number of records to display | Find orthologs in
Organism | Name | Ortholog group | Product | Weight |
---|---|---|---|---|
M. tuberculosis | Rv2257c | OG5_229489 | Conserved protein | 21 |
M. tuberculosis | Rv1627c | OG5_146299 | Probable nonspecific lipid-transfer protein | 20 |
M. tuberculosis | Rv3111 | OG5_129779 | Probable molybdenum cofactor biosynthesis protein C MoaC1 | 19 |
M. tuberculosis | Rv3602c | OG5_129569 | Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activatin ... | 19 |
M. tuberculosis | Rv3819 | No group | Unknown protein | 19 |
M. tuberculosis | Rv2032 | OG5_179425 | Conserved protein Acg | 17 |
M. tuberculosis | Rv3775 | OG5_139404 | Probable lipase LipE | 17 |
M. tuberculosis | Rv2875 | OG5_133411 | Major secreted immunogenic protein Mpt70 | 17 |
M. tuberculosis | Rv2591 | OG5_129879 | PE-PGRS family protein PE_PGRS44 | 17 |
M. tuberculosis | Rv2353c | OG5_132376 | PPE family protein PPE39 | 17 |
M. tuberculosis | Rv2237 | OG5_163412 | Conserved protein | 17 |
M. tuberculosis | Rv2468c | OG5_237676 | Conserved protein | 17 |
M. tuberculosis | Rv2632c | OG5_239144 | Conserved protein | 17 |
M. tuberculosis | Rv3377c | OG5_163665 | Halimadienyl diphosphate synthase | 17 |
M. tuberculosis | Rv0752c | OG5_136059 | Probable acyl-CoA dehydrogenase FadE9 | 16 |
M. tuberculosis | Rv1270c | No group | Possible lipoprotein LprA | 16 |
M. tuberculosis | Rv0623 | OG5_204775 | Possible antitoxin VapB30 | 16 |
M. tuberculosis | Rv1159A | OG5_127905 | Unknown protein | 16 |
M. tuberculosis | Rv1588c | OG5_151920 | Partial REP13E12 repeat protein | 16 |
M. tuberculosis | Rv1990c | OG5_239149 | Probable transcriptional regulatory protein | 16 |
M. tuberculosis | Rv2079 | OG5_161998 | Conserved hypothetical protein | 16 |
M. tuberculosis | Rv2098c | No group | PE-PGRS family protein PE_PGRS36 | 15 |
M. tuberculosis | Rv0155 | OG5_127241 | Probable NAD(P) transhydrogenase (subunit alpha) PntAa [first part; catalytic pa ... | 15 |
M. tuberculosis | Rv0706 | OG5_128312 | 50S ribosomal protein L22 RplV | 15 |
M. tuberculosis | Rv0306 | OG5_146497 | Putative oxidoreductase | 15 |