Target list

Search results for query: top-100 of ranked list for PLOS-NTD; Posted List 336, No tissue-differential gene expression data

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Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.


98 records found | Showing page 1 of 4 (records 1-25) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product
S. mansoni   Smp_155270   OG5_190385   hydroxymethylglutaryl-CoA synthase
S. mansoni   Smp_004810.3   OG5_126821   protein phosphatase type 1
S. mansoni   Smp_027920   OG5_126605   tubulin subunit alpha
S. mansoni   Smp_121430.2   OG5_127761   proteasome subunit beta 3 (T01 family)
S. mansoni   Smp_025010   OG5_126846   casein kinase II beta subunit
S. mansoni   Smp_090120.2   OG5_126605   alpha tubulin
S. mansoni   Smp_025800   OG5_127834   proteasome subunit beta 1 (T01 family)
S. mansoni   Smp_079770.1   OG5_126843   protein disulfide-isomerase er-60 precursor (erp60)
S. mansoni   Smp_046060.1   OG5_126577   myosin heavy chain type B
S. mansoni   Smp_171540.1   OG5_162739   Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp)
S. mansoni   Smp_147050   OG5_127237   ATP synthase alpha subunit vacuolar
S. mansoni   Smp_079760.1   OG5_132787   protein kinase
S. mansoni   Smp_144030   OG5_127441   phosphatidate cytidylyltransferase
S. mansoni   Smp_052810   OG5_127121   glucose-6-phosphate 1-dehydrogenase
S. mansoni   Smp_059790.1   OG5_126720   transketolase
S. mansoni   Smp_138590   OG5_127955   hydroxymethylglutaryl-CoA reductase (NADPH)
S. mansoni   Smp_060950   OG5_127387   soluble NSF attachment protein (SNAP)
S. mansoni   Smp_192110   OG5_126611   tubulin subunit beta
S. mansoni   Smp_016780   OG5_126605   tubulin subunit alpha
S. mansoni   Smp_034840.2   OG5_126706   hypothetical protein
S. mansoni   Smp_142050   OG5_126781   serine/threonine protein kinase
S. mansoni   Smp_041600   OG5_126684   isoleucine--tRNA ligase
S. mansoni   Smp_029390   OG5_127061   ATP synthase subunit beta vacuolar
S. mansoni   Smp_034490   OG5_127762   proteasome catalytic subunit 1 (T01 family)
S. mansoni   Smp_035760   OG5_126611   tubulin subunit beta