Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.
28 records found | Showing page 1 of 2 (records 1-25) | Number of records to display | Find orthologs in
| Organism | Name | Ortholog group | Product |
|---|---|---|---|
| B. malayi | Bm1_00150 | No group | hexokinase type II |
| B. malayi | Bm1_00615 | OG5_132277 | adenylate cyclase, type IX |
| B. malayi | Bm1_01930 | OG5_126758 | 6-phosphofructokinase |
| B. malayi | Bm1_03085 | No group | glutamyl-tRNA synthetase |
| B. malayi | Bm1_04665 | OG5_129051 | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase |
| B. malayi | Bm1_06755 | OG5_126929 | endochitinase |
| B. malayi | Bm1_07420 | OG5_126691 | aconitate hydratase, mitochondrial |
| B. malayi | Bm1_09045 | OG5_127143 | fructose-bisphosphate aldolase 2 |
| B. malayi | Bm1_09150 | OG5_126916 | guanylate kinase |
| B. malayi | Bm1_10280 | OG5_126720 | transketolase |
| B. malayi | Bm1_13790 | OG5_126886 | adenylate kinase isoenzyme 1 |
| B. malayi | Bm1_17035 | OG5_126929 | endochitinase |
| B. malayi | Bm1_17695 | No group | enteropeptidase precursor |
| B. malayi | Bm1_18670 | OG5_127627 | lactoylglutathione lyase |
| B. malayi | Bm1_19855 | OG5_127452 | cyclophilin-type peptidyl-prolyl cis-trans isomerase-18, Bmcyp-18 |
| B. malayi | Bm1_24575 | OG5_126762 | adenylate kinase isoenzyme 1 |
| B. malayi | Bm1_26915 | OG5_214740 | pyruvate kinase, muscle isozyme |
| B. malayi | Bm1_27025 | OG5_126758 | 6-phosphofructokinase |
| B. malayi | Bm1_28580 | OG5_127154 | bifunctional aminoacyl-tRNA synthetase |
| B. malayi | Bm1_30285 | No group | cytosol aminopeptidase |
| B. malayi | Bm1_31540 | OG5_126779 | 2-oxoglutarate dehydrogenase E1 component, mitochondrial precursor |
| B. malayi | Bm1_32295 | No group | glycerol-3-phosphate dehydrogenase, cytoplasmic, putative |
| B. malayi | Bm1_32300 | No group | glycerol-3-phosphate dehydrogenase |
| B. malayi | Bm1_35915 | No group | pyruvate kinase |
| B. malayi | Bm1_40465 | OG5_143028 | Cuticular glutathione peroxidase precursor |