Detailed view for Tb927.8.1020

Basic information

TDR Targets ID: 14444
Trypanosoma brucei, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Source Database / ID:  TriTrypDB  GeneDB

pI: 6.2362 | Length (AA): 702 | MW (Da): 78917 | Paralog Number: 1

Signal peptide: N | GPI Anchor: | Predicted trans-membrane segments: 0

Druggability Group : DG4

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00300   Histidine phosphatase superfamily (branch 1)
PF01591   6-phosphofructo-2-kinase

Gene Ontology

Mouse over links to read term descriptions.
GO:0019203   carbohydrate phosphatase activity  
GO:0006003   fructose 2,6-bisphosphate metabolic process  
GO:0005575   cellular_component  
GO:0005524   ATP binding  
GO:0003873   6-phosphofructo-2-kinase activity  
GO:0003824   catalytic activity  
GO:0006096   glycolysis  
GO:0006000   fructose metabolic process  

Metabolic Pathways

Fructose and mannose metabolism (KEGG)

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

Upregulation Percent Ranking Stage Dataset
Mid 40-60% percentile Procyclic, Bloodstream Form. Siegel TN
Show/Hide expression data references
  • Siegel TN Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites.

Orthologs

Ortholog group members (OG5_126873)

Species Accession Gene Product
Arabidopsis thaliana AT1G07110   6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
Candida albicans CaO19.6423   fructose-2,6-biphosphatase
Candida albicans CaO19.13781   fructose-2,6-biphosphatase
Caenorhabditis elegans CELE_K02B2.1   Protein K02B2.1
Caenorhabditis elegans CELE_Y110A7A.6   Protein Y110A7A.6, isoform B
Dictyostelium discoideum DDB_G0276253   hypothetical protein
Dictyostelium discoideum DDB_G0282759   hypothetical protein
Drosophila melanogaster Dmel_CG3400   6-phosphofructo-2-kinase
Escherichia coli b0638   putative alpha-ribazole-5'-P phosphatase
Echinococcus granulosus EgrG_000638700   6 phosphofructo 2 kinase:fructose 2
Entamoeba histolytica EHI_103650   phosphoglycerate mutase family protein, putative
Echinococcus multilocularis EmuJ_000638700   6 phosphofructo 2 kinase:fructose 2
Giardia lamblia GL50803_135885   Hypothetical protein
Giardia lamblia GL50803_135886   Hypothetical protein
Homo sapiens ENSG00000123836   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Homo sapiens ENSG00000158571   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Homo sapiens ENSG00000114268   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Homo sapiens ENSG00000170525   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Leishmania braziliensis LbrM.03.0700   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Leishmania braziliensis LbrM.07.0840   6-phosphofructo-2-kinase-like protein
Leishmania donovani LdBPK_070870.1   6-phosphofructo-2-kinase-like protein
Leishmania donovani LdBPK_030790.1   6-phosphofructo-2-kinase 1
Leishmania infantum LinJ.03.0790   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Leishmania infantum LinJ.07.0870   6-phosphofructo-2-kinase-like protein
Leishmania major LmjF.07.0760   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Leishmania major LmjF.03.0800   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Leishmania mexicana LmxM.03.0800  
Leishmania mexicana LmxM.07.0760   6-phosphofructo-2-kinase-like protein
Loa Loa (eye worm) LOAG_13898   hypothetical protein
Loa Loa (eye worm) LOAG_11483   hypothetical protein
Loa Loa (eye worm) LOAG_12488   hypothetical protein
Mus musculus ENSMUSG00000025271   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Mus musculus ENSMUSG00000026409   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
Mus musculus ENSMUSG00000025648   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Mus musculus ENSMUSG00000026773   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Mycobacterium ulcerans MUL_4172   fructose-2,6-bisphosphatase GpmB
Mycobacterium ulcerans MUL_4380   hypothetical protein
Oryza sativa 4332523   Os03g0294200
Oryza sativa 4337906   Os05g0164100
Onchocerca volvulus OVOC11690  
Saccharomyces cerevisiae YJL155C   Fbp26p
Schistosoma japonicum Sjp_0078350   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3, putative
Schistosoma japonicum Sjp_0076750   ko:K00900 6-phosphofructo-2-kinase [EC2.7.1.105], putative
Schistosoma japonicum Sjp_0044610   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2, putative
Schistosoma mansoni Smp_015710   6-phosphofructokinase
Schmidtea mediterranea mk4.000446.00   6-phosphofructo-2-kinase
Schmidtea mediterranea mk4.012484.00  
Schmidtea mediterranea mk4.005599.02  
Schmidtea mediterranea mk4.016331.00  
Schmidtea mediterranea mk4.007494.04  
Schmidtea mediterranea mk4.000454.15  
Schmidtea mediterranea mk4.006687.00  
Trypanosoma brucei gambiense Tbg972.3.2780   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Trypanosoma brucei gambiense Tbg972.8.600   fructose-6-phosphate2-kinase, putative
Trypanosoma brucei Tb927.8.1020   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Trypanosoma brucei Tb927.3.2710   6-phosphofructo-2-kinase 2
Trypanosoma congolense TcIL3000_3_1660   6-phosphofructo-2-kinase 1
Trypanosoma congolense TcIL3000_8_600   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Trypanosoma cruzi TcCLB.508181.20   6-phosphofructo-2-kinase 1
Trypanosoma cruzi TcCLB.508569.130   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Trypanosoma cruzi TcCLB.503733.20   6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Trypanosoma cruzi TcCLB.508153.950   6-phosphofructo-2-kinase 1

Essentiality

Tb927.8.1020 has direct evidence of essentiality
Gene/Ortholog Organism Phenotype Source Study
Tb927.3.2710 Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (3 days) alsford
Tb927.3.2710 Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (6 days) alsford
Tb927.3.2710 Trypanosoma brucei no significant loss or gain of fitness in procyclic forms alsford
Tb927.3.2710 Trypanosoma brucei no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms alsford
Tb927.8.1020 this record Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (3 days) alsford
Tb927.8.1020 this record Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (6 days) alsford
Tb927.8.1020 this record Trypanosoma brucei no significant loss or gain of fitness in procyclic forms alsford
Tb927.8.1020 this record Trypanosoma brucei no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms alsford
b0638 Escherichia coli non-essential goodall
Show/Hide essentiality data references
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database

Phenotypes and Validation (curated)

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Drugs/Inhibitors
cell proliferation (GO:0008283) normal (PATO:0000461) bloodstream stage trypomastigotes (PLO:0027) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: normal cell proliferation (no significant loss or gain of fitness) in bloodstream forms (stage 6 days). References: 21363968
cell proliferation (GO:0008283) normal (PATO:0000461) procyclic (PLO:0034) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: normal cell proliferation (no significant loss or gain of fitness) in differentiation of procyclic to bloodstream forms . References: 21363968

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 Compounds References
Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 Compounds References
Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Compounds References
Homo sapiens 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model

Ranking Plot

Putative Drugs List

Compound Raw Global Species
0.007 1 1
0.4345 1 1
0.0416 1 1
0.1082 1 1
0.4505 1 1
0.715 0.5301 1
0.324 1 1
0.1149 1 1
0.3981 1 1
0.7816 1 1
0.199 1 1
0.4714 1 1
0.007 1 1
0.0559 0.4287 1
0.0553 1 1
0.1736 0.4967 1
0.006 1 1
0.0141 1 1
0.139 1 1
0.0229 1 1
0.7816 1 1
0.1465 0.2605 1
0.3981 1 1
0.099 0.4197 0.4161
0.0066 1 1
0.4529 1 1
0.715 0.5301 1
0.0901 0.3711 1
0.0134 1 1
0.3492 0.5669 0.5667
0.0347 1 1
0.0451 1 1
0.7816 1 1
0.007 1 1
0.2877 1 1
0.1924 1 1
0.1546 1 1
0.2906 1 1
0.7816 1 1
0.2276 1 1
0.0141 1 1
0.1866 0.7226 1
0.1923 1 1
0.007 1 1
0.1439 1 1
0.007 1 1
0.0306 0.7078 1
0.4154 1 1
0.0301 1 1
0.4613 0.2914 1
0.3504 0.7363 1
0.007 1 1
0.7816 1 1
0.1736 0.4967 1
0.0211 1 1
0.2318 1 1
0.2992 0.6136 0.6136
0.1177 1 1
0.4667 1 1
0.024 0.2505 1
0.013 1 1
0.0211 1 1
0.4311 1 1
0.2602 0.4923 1
0.1754 0.7096 1
0.5487 1 1
0.0141 1 1
0.715 0.5301 1
0.4002 1 1
0.2877 1 1
0.3492 0.5669 0.5667
0.3637 1 1
0.2673 1 1
0.0478 0.8645 1
0.0476 1 1
0.0237 1 1
0.1736 0.4967 1
0.325 1 1
0.3585 1 1
0.0376 1 1
0.2464 1 1
0.4136 1 1
0.1094 0.7876 1
0.7816 1 1
0.1235 1 1
0.0211 1 1
0.4389 1 1
0.7816 1 1
0.0706 1 1
0.1254 1 1
0.007 1 1
0.715 0.5301 1
0.0116 0.3281 1
0.2612 0.5264 1
0.413 1 1
0.007 1 1
0.007 1 1
0.064 1 1
0.3357 0.4396 0.4395
0.1509 1 1
0.3739 1 1
0.1924 1 1
0.0376 0.309 1
0.2972 1 1
0.2309 1 1
0.4321 1 1
0.7816 1 1
0.2913 1 1
0.2602 0.4923 1
0.1502 1 1
0.007 1 1
0.1597 1 1
0.0141 1 1
0.0654 0.395 0.3933
0.0211 1 1
0.0119 0.3408 1
0.4261 1 1
0.4335 1 1
0.2388 0.9993 1
0.007 1 1
0.007 1 1
0.1927 0.8789 1
0.024 0.3485 1
0.4154 1 1
0.2309 1 1
0.4211 1 1
0.0141 1 1
0.0208 1 1
0.4154 1 1
0.2878 1 1
0.3689 1 1
0.007 1 1
0.0211 1 1
0.4044 1 1
0.5404 1 1
0.1428 1 1
0.2129 1 1
0.0064 1 1
0.0971 1 1
0.0427 1 1
0.5965 1 1
0.1235 1 1
0.007 1 1
0.4516 1 1
0.4019 1 1
0.007 1 1
0.324 1 1
0.4583 1 1
0.3981 1 1
0.5404 1 1
0.5574 0.9906 1
0.5965 1 1
0.0376 1 1
0.007 1 1
0.1248 1 1
0.0826 1 1
0.0488 0.4694 1
0.3438 1 1
0.15 1 1
0.4565 1 1
0.715 0.5301 1
0.0194 0.9775 1
0.006 0.3213 1
0.0559 0.4287 1
0.4558 1 1
0.2258 1 1
0.0367 0.3617 1
0.007 1 1
0.2806 1 1
0.1977 1 1
0.0211 0.2603 1
0.4473 1 1
0.109 1 1
0.024 0.2505 1
0.1289 0.3006 1
0.007 1 1
0.5818 1 1
0.08 1 1
0.2602 0.4923 1
0.4189 1 1
0.2813 1 1
0.2304 1 1
0.0967 1 1
0.007 1 1
0.7816 1 1
0.3401 1 1
0.0355 1 1
0.2088 1 1
0.007 1 1
0.4457 1 1
0.2865 1 1
0.007 1 1
0.007 1 1
0.007 1 1
0.138 0.5684 1
0.4132 1 1
0.2103 1 1
0.3335 1 1
0.0293 1 1
0.2938 1 1
0.007 1 1
0.1829 1 1
0.0563 0.3832 1
0.3658 1 1
0.3504 0.7363 1
0.1924 1 1
0.2312 1 1
0.0242 1 1
0.3402 1 1
0.3211 1 1
0.2602 0.4923 1
0.0901 0.3711 1
0.007 1 1
0.3279 1 1
0.007 1 1
0.0519 1 1
0.1382 1 1
0.0119 1 1
0.007 1 1
0.3056 1 1
0.0957 1 1
0.3492 0.5669 0.5667
0.0211 1 1
0.3236 1 1
0.0069 0.2892 1
0.0324 1 1
0.2534 1 1
0.6185 1 1
0.15 1 1
0.715 0.5301 1
0.4743 1 1
0.5036 1 1
0.0297 1 1
0.3123 1 1
0.2136 1 1
0.5866 1 1
0.007 1 1
0.007 1 1
0.2285 1 1
0.0351 1 1
0.3242 1 1
0.007 1 1
0.3782 1 1
0.2486 1 1
0.196 1 1
0.4743 1 1
0.2714 1 1
0.3924 1 1
0.3552 0.6841 1
0.3971 1 1
0.4613 0.2914 1
0.013 1 1
0.4662 1 1
0.6145 1 1
0.007 1 1
0.0563 0.3832 1
0.3704 1 1
0.196 1 1
0.1383 1 1
0.0342 0.7273 1
0.3981 1 1
0.0606 1 1
0.4554 1 1
0.0994 1 1
0.3357 0.4396 0.4395
0.007 1 1
0.577 1 1
0.2032 0.6418 1
0.0175 0.4357 1
0.4529 1 1
0.0428 1 1
0.059 0.579 1
0.4002 1 1
0.4129 1 1
0.2602 0.4923 1
0.4311 1 1
0.3925 1 1
0.2469 1 1
0.0266 0.7683 0.7657
0.1345 1 1
0.2486 1 1
0.0353 0.3814 1
0.007 1 1
0.0314 0.7145 1
0.4308 0.771 0.771
0.5108 1 1
0.6029 1 1
0.3024 1 1
0.0653 0.6984 1
0.007 1 1
0.007 1 1
0.715 0.5301 1
0.1327 0.3214 1
0.2714 1 1
0.007 1 1
0.0301 0.888 1
0.1754 0.7096 1
0.4743 1 1
0.1076 1 1
0.0356 1 1
0.715 0.5301 1
0.44 1 1
0.007 1 1
0.2081 1 1
0.3571 1 1
0.3357 0.4396 0.4395
0.1924 1 1
0.007 1 1
0.0254 1 1
0.007 1 1
0.007 1 1
0.2121 1 1
0.4529 1 1
0.007 1 1
0.0113 0.6202 1
0.1977 1 1
0.1483 0.6272 1
0.5108 1 1
0.1908 1 1
0.4554 1 1
0.007 1 1
0.2374 1 1
0.2032 0.6418 1
0.2602 0.4923 1
0.3172 0.5252 1
0.4716 1 1
0.7816 1 1
0.2602 0.4923 1
0.2749 1 1
0.2465 1 1
0.3822 1 1
0.3565 1 1
0.052 1 1
0.191 1 1
0.007 1 1
0.043 1 1
0.0435 0.8537 1
0.012 1 1
0.007 1 1
0.3357 0.4396 0.4395
0.1754 0.7096 1
0.007 1 1
0.0563 0.3832 1
0.0832 1 1
0.5767 1 1
0.4308 0.771 0.771
0.4345 1 1
0.0443 1 1
0.3585 1 1
0.0188 0.2639 1
0.0139 0.3631 0.3631
0.4389 1 1
0.4157 1 1
0.3864 1 1
0.4583 1 1
0.007 1 1
0.1785 0.5127 1
0.3504 0.7363 1
0.1295 1 1
0.0061 1 1
0.007 1 1
0.2911 1 1
0.1687 1 1
0.2285 1 1
0.0433 1 1
0.3699 1 1
0.2624 1 1
0.0141 1 1
0.1736 0.4967 1
0.0118 1 1
0.3601 1 1
0.0655 1 1
0.1736 0.4967 1
0.4529 1 1
0.9087 0.666 1
0.2661 1 1
0.44 1 1
0.9087 0.666 1
0.0057 0.2552 1
0.0552 1 1
0.4558 1 1
0.0272 0.2871 1
0.1541 1 1
0.0141 1 1
0.2781 1 1
0.007 1 1
0.1866 0.7226 1
0.2771 1 1
0.1866 0.7226 1
0.1235 1 1
0.2207 1 1
0.0139 1 1
0.5574 0.9906 1
0.4687 1 1
0.2197 1 1
0.3658 1 1
0.0624 0.5045 1
0.4911 1 1
0.1995 1 1
0.3814 1 1
0.3981 1 1
0.4396 1 1
0.2602 0.4923 1
0.2714 1 1
0.1636 1 1
0.007 1 1
0.0171 1 1
0.4962 1 1
0.0252 1 1
0.2843 0.2627 0.2627
0.1934 1 1
0.1203 0.5349 1
0.3981 1 1
0.715 0.5301 1
0.5108 1 1
0.2906 1 1
0.007 1 1
0.0248 1 1
0.4301 1 1
0.3242 1 1
0.007 1 1
0.1927 0.8789 1
0.0139 0.3631 0.3631
0.2843 0.2627 0.2627
0.1866 0.7226 1
0.044 1 1
0.007 1 1
0.3238 0.8029 1
0.007 1 1
0.1601 1 1
0.007 1 1
0.0602 1 1
0.0234 0.253 0.2519
0.3238 0.8029 1
0.1443 1 1
0.0069 0.2892 1
0.0114 0.3603 0.0218
0.3322 1 1
0.1785 0.5127 1
0.4389 1 1
0.0297 1 1
0.5982 1 1
0.173 1 1
0.159 1 1
0.4132 1 1
0.007 1 1
0.3366 1 1
0.0209 0.5166 1
0.2137 0.99 1
0.2937 1 1
0.007 1 1
0.4002 1 1
0.0211 1 1
0.0136 0.2576 1
0.0211 1 1
0.1632 1 1
0.1465 0.2605 1
0.3492 0.5669 0.5667
0.1327 0.3214 1
0.3814 1 1
0.138 0.5684 1
0.7816 1 1
0.007 1 1
0.371 1 1
0.1765 1 1
0.2602 0.4923 1
0.3401 1 1
0.1203 0.5349 1
0.2309 1 1
0.715 0.5301 1
0.0363 0.4729 1
0.2287 1 1
0.0065 1 1
0.1849 1 1
0.2081 1 1
0.0446 1 1
0.0121 1 1
0.042 0.7626 0.7626
0.007 1 1
0.042 0.7626 0.7626
0.0304 0.7044 1
0.3545 1 1
0.0242 1 1
0.24 1 1
0.0248 0.8912 0.8912
0.4395 1 1
0.3179 1 1
0.2081 1 1
0.3366 1 1
0.2602 0.4923 1
0.0136 1 1
0.0669 0.6343 1
0.0116 0.3281 1
0.4039 1 1
0.4554 1 1
0.715 0.5301 1
0.007 1 1
0.383 1 1
0.3921 1 1
0.0377 1 1
0.0249 0.3601 1
0.1628 1 1
0.3279 1 1
0.007 1 1
0.3552 0.6841 1
0.007 1 1
0.4211 1 1
0.2771 1 1
0.715 0.5301 1
0.8446 1 1
0.007 1 1
0.0114 1 1
0.0474 1 1
0.0238 0.5665 1
0.5194 1 1
0.715 0.5301 1
0.1943 1 1
0.0624 0.5043 1
0.265 1 1
0.026 1 1
0.007 1 1
0.715 0.5301 1
0.2602 0.4923 1
0.0456 1 1
0.007 1 1
0.3366 1 1
0.007 1 1
0.0208 1 1
0.0129 1 1
0.3791 1 1
0.08 1 1
0.007 1 1
0.3228 1 1
0.0418 1 1
0.1029 1 1
0.5452 1 1
0.0948 1 1
0.2197 1 1
0.3725 1 1
0.0474 1 1
0.1387 0.3219 0.3214
0.2137 0.99 1
0.0302 1 1
0.3915 1 1
0.526 1 1
0.4529 1 1
0.2806 1 1
0.2321 1 1
0.3161 1 1
0.3357 0.4396 0.4395
0.0563 0.3832 1
0.7741 1 1
0.3912 1 1
0.0379 0.9889 1
0.2182 1 1
0.0211 1 1
0.0059 1 1
0.2287 1 1
0.2137 0.99 1
0.099 0.4197 0.4161
0.0057 0.2552 1
0.3924 1 1
0.1754 0.7096 1
0.013 1 1
0.079 1 1
0.4282 1 1
0.007 1 1
0.0364 1 1
0.024 0.3485 1
0.2602 0.4923 1
0.041 1 1
0.2972 1 1
0.1649 0.9268 1
0.4479 1 1
0.1289 0.3006 1
0.0187 0.6495 1
0.1736 0.4967 1
0.2465 1 1
0.0641 1 1
0.007 1 1
0.2287 1 1
0.007 1 1
0.007 1 1
0.1387 0.3219 0.3214
0.011 1 1
0.007 1 1
0.0563 0.3832 1
0.0376 0.309 1
0.0141 1 1
0.007 1 1
0.715 0.5301 1
0.007 1 1
0.4691 1 1
0.1636 1 1
0.0162 1 1
0.0432 1 1
0.3024 1 1
0.007 1 1
0.3981 1 1
0.3504 0.7363 1
0.0263 1 1
0.007 1 1
0.0605 1 1
0.2032 0.6418 1
0.007 1 1
0.007 1 1
0.4211 1 1
0.4247 1 1
0.007 1 1
0.0297 1 1
0.0122 1 1
0.0211 1 1
0.0057 1 1
0.0064 1 1
0.4308 0.771 0.771
0.3357 0.4396 0.4395
0.064 1 1
0.2409 1 1
0.3585 1 1
0.0706 1 1
0.0176 1 1
0.089 1 1
0.1635 1 1
0.0234 0.253 0.2519
0.007 1 1
0.5866 1 1
0.0236 1 1
0.0445 1 1
0.0564 0.6867 0.0646
0.1936 1 1
0.0096 0.2801 0.2801
0.1161 0.7272 1
0.0563 0.3832 1
0.007 1 1
0.1504 1 1
0.324 1 1
0.007 1 1
0.007 1 1
0.4463 1 1
0.0246 1 1
0.1084 1 1
0.007 1 1
0.5404 1 1
0.577 1 1
0.1531 1 1
0.3228 1 1
0.007 1 1
0.2749 1 1
0.0266 0.7683 0.7657
0.5149 1 1
0.2088 1 1
0.6441 1 1
0.007 1 1
0.7816 1 1
0.2731 1 1
0.007 1 1
0.4395 1 1
0.3642 1 1
0.007 1 1
0.1365 1 1
0.1891 1 1
0.007 1 1
0.007 1 1
0.2388 0.9993 1
0.1649 0.9268 1
0.3209 1 1
0.007 1 1
0.477 1 1
0.007 1 1
0.0237 0.3333 1
0.4864 1 1
0.3921 1 1
0.1833 1 1
0.007 1 1
0.4817 1 1
0.007 1 1
0.5263 1 1
0.4529 1 1
0.0108 1 1
0.577 1 1
0.007 1 1
0.1849 1 1
0.2843 0.2627 0.2627
0.1094 0.7876 1
0.0559 1 1
0.3236 1 1
0.0121 1 1
0.007 1 1
0.2129 1 1
0.3648 1 1
0.095 1 1
0.2795 1 1
0.0235 0.3079 1
0.2731 1 1
0.4257 1 1
0.3228 1 1
0.0459 0.705 1
0.0133 0.3289 1
0.9087 0.666 1
0.7816 1 1
0.4002 1 1
0.07 1 1
0.6029 1 1
0.1472 1 1
0.1966 1 1
0.0298 1 1
0.4182 1 1
0.007 1 1
0.0373 1 1
0.007 1 1
0.0324 1 1
0.1046 1 1
0.1566 1 1
0.3357 0.4396 0.4395
0.0136 0.4607 0.4607
0.0417 0.5082 1
0.3504 0.7363 1
0.4045 1 1
0.0414 1 1
0.007 1 1
0.4062 1 1
0.2321 1 1
0.715 0.5301 1
0.0423 1 1
0.007 1 1
0.1068 1 1
0.2992 0.6136 0.6136
0.4558 1 1
0.0624 0.5045 1
0.1924 1 1
0.2375 1 1
0.8693 1 1
0.2602 0.4923 1
0.4554 1 1
0.1084 1 1
0.218 1 1
0.0429 1 1
0.3981 1 1
0.7816 1 1
0.0118 1 1
0.007 1 1
0.2333 1 1
0.715 0.5301 1
0.0115 1 1
0.2137 0.99 1
0.007 1 1
0.1805 1 1
0.0324 1 1
0.4714 1 1
0.0058 1 1
0.4565 1 1
0.007 1 1
0.3949 1 1
0.5047 1 1
0.1849 1 1
0.0182 0.268 0.7684
0.1883 1 1
0.011 1 1
0.1497 1 1
0.3648 1 1
0.7816 1 1
0.715 0.5301 1
0.1891 1 1
0.2081 1 1
0.503 1 1
0.2878 1 1
0.4389 1 1
0.0705 0.4799 1
0.007 1 1
0.0198 1 1
0.1714 1 1
0.07 1 1
0.2088 1 1
0.5487 1 1
0.3864 1 1
0.2032 0.6418 1
0.167 1 1
0.5395 1 1
0.3438 1 1
0.0116 0.3332 1
0.007 1 1
0.0211 1 1
0.0417 0.5082 1
0.007 1 1
0.006 1 1
0.715 0.5301 1
0.0175 0.4357 1
0.2463 1 1
0.1765 1 1
0.1158 1 1
0.0448 1 1
0.265 1 1
0.0064 1 1
0.4505 1 1

Assayability

Assay information

No assay information for this target.

Reagent availability

  • Reagent:
  • Target Type Source Notes
    Tb927.8.1020 cloned gene BRENDA A gene with this EC number or name or sequence has been cloned from Trypanosoma brucei ( 1 )

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

No user comments are available for this gene. Log in to add comments, or register.

Enter your comment

User ()
Gene identifier Tb927.8.1020 (Trypanosoma brucei), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase, putative
Title for this comment
Comment