Detailed view for Tb927.9.7180

Basic information

TDR Targets ID: 15129
Trypanosoma brucei, adenosine monophosphate deaminase, putative

Source Database / ID:  TriTrypDB  GeneDB

pI: 6.1554 | Length (AA): 1690 | MW (Da): 189711 | Paralog Number: 3

Signal peptide: N | GPI Anchor: | Predicted trans-membrane segments: 0

Druggability Group : DG4

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00962   Adenosine/AMP deaminase

Gene Ontology

Mouse over links to read term descriptions.
GO:0032264   IMP salvage  
GO:0005575   cellular_component  
GO:0003876   AMP deaminase activity  
GO:0019239   deaminase activity  
GO:0009168   purine ribonucleoside monophosphate biosynthetic process  

Structural information

Modbase 3D models:

There are 7 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
41 86 5c1m (A) 231 276 28.00 0.73 0.01 0.31758 3.99
141 712 2a3l (A) 251 836 31.00 0 1 0.727262 -0.5
782 1367 2a3l (A) 236 826 37.00 0 1 0.806946 -0.61
1324 1551 5xg2 (A) 355 806 12.00 0.0034 0.02 0.199711 -0.04
1377 1552 3na7 (A) 6 178 16.00 0.09 0.02 0.259942 -0.35
1379 1462 3u59 (A) 10 84 36.00 0.21 0.04 0.187504 0.18
1380 1518 3rf3 (A) 122 257 16.00 0 0.28 0.361449 -1.4

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

Upregulation Percent Ranking Stage Dataset
Upper 60-80% percentile Procyclic. Siegel TN
Upregulation Percent Ranking Stage Dataset
Mid 40-60% percentile Bloodstream Form. Siegel TN
Show/Hide expression data references
  • Siegel TN Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites.

Orthologs

Ortholog group members (OG5_126856)

Species Accession Gene Product
Arabidopsis thaliana AT2G38280   AMP deaminase
Brugia malayi Bm1_54650   adenosine monophosphate deaminase
Candida albicans CaO19.8510   Adenosine/AMP deaminase similar to S. cerevisiae AMD1 (YML035C) involved in purine nucleotide metabolism
Candida albicans CaO19.891   Adenosine/AMP deaminase similar to S. cerevisiae AMD1 (YML035C) involved in purine nucleotide metabolism
Caenorhabditis elegans CELE_C34F11.3   Protein C34F11.3, isoform B
Cryptosporidium hominis Chro.40214   AMP deaminase
Cryptosporidium parvum cgd4_1890   adenosine monophosphate deaminase 2
Dictyostelium discoideum DDB_G0292266   AMP deaminase
Drosophila melanogaster Dmel_CG32626   AMP deaminase
Echinococcus granulosus EgrG_000392900   AMP deaminase 2
Entamoeba histolytica EHI_029100   AMP deaminase, putative
Entamoeba histolytica EHI_120890   AMP deaminase, putative
Echinococcus multilocularis EmuJ_000392900   AMP deaminase 2
Homo sapiens ENSG00000133805   adenosine monophosphate deaminase 3
Homo sapiens ENSG00000116748   adenosine monophosphate deaminase 1
Homo sapiens ENSG00000116337   adenosine monophosphate deaminase 2
Leishmania braziliensis LbrM.04.0320   adenosine monophosphate deaminase, putative,AMP deaminase, putative
Leishmania braziliensis LbrM.32.2780   AMP deaminase, putative,adenosine monophosphate deaminase-like protein
Leishmania braziliensis LbrM.34.4760   AMP deaminase, putative
Leishmania braziliensis LbrM.13.0790   AMP deaminase, putative,amp deaminase-like protein
Leishmania donovani LdBPK_322690.1   AMP deaminase, putative
Leishmania donovani LdBPK_040270.1   adenosine monophosphate deaminase, putative
Leishmania donovani LdBPK_354860.1   AMP deaminase, putative
Leishmania donovani LdBPK_130870.1   AMP deaminase, putative
Leishmania infantum LinJ.32.2690   AMP deaminase, putative,adenosine monophosphate deaminase-like protein
Leishmania infantum LinJ.35.4860   AMP deaminase, putative
Leishmania infantum LinJ.04.0270   adenosine monophosphate deaminase, putative,AMP deaminase, putative
Leishmania infantum LinJ.13.0870   AMP deaminase, putative,amp deaminase-like protein
Leishmania major LmjF.13.0980   AMP deaminase, putative,amp deaminase-like protein
Leishmania major LmjF.32.2550   AMP deaminase, putative,adenosine monophosphate deaminase-like protein
Leishmania major LmjF.35.4800   AMP deaminase, putative
Leishmania major LmjF.04.0280   adenosine monophosphate deaminase, putative,AMP deaminase, putative
Leishmania mexicana LmxM.13.0980   AMP deaminase, putative,amp deaminase-like protein
Leishmania mexicana LmxM.31.2550   AMP deaminase, putative,adenosine monophosphate deaminase-like protein
Leishmania mexicana LmxM.04.0280   adenosine monophosphate deaminase, putative,AMP deaminase, putative
Leishmania mexicana LmxM.34.4800   AMP deaminase, putative
Loa Loa (eye worm) LOAG_06535   hypothetical protein
Loa Loa (eye worm) LOAG_06536   AMP deaminase
Mus musculus ENSMUSG00000070385   adenosine monophosphate deaminase 1
Mus musculus ENSMUSG00000005686   adenosine monophosphate deaminase 3
Mus musculus ENSMUSG00000027889   adenosine monophosphate deaminase 2
Neospora caninum NCLIV_049460   adenosine monophosphate deaminase, putative
Oryza sativa 4344386   Os07g0693500
Oryza sativa 4338495   Os05g0349200
Onchocerca volvulus OVOC3634   AMP deaminase 2 homolog
Plasmodium berghei PBANKA_1344400   AMP deaminase, putative
Plasmodium falciparum PF3D7_1329400   AMP deaminase, putative
Plasmodium knowlesi PKNH_1271000   AMP deaminase, putative
Plasmodium vivax PVX_082415   adenosine/AMP deaminase, putative
Plasmodium yoelii PY01044   AMP deaminase homolog
Saccharomyces cerevisiae YML035C   AMP deaminase
Schistosoma japonicum Sjp_0036970   ko:K01490 AMP deaminase [EC3.5.4.6], putative
Schistosoma japonicum Sjp_0121980   AMP deaminase 2, putative
Schistosoma mansoni Smp_004120   AMP deaminase
Schmidtea mediterranea mk4.006992.03   AMP deaminase 2
Schmidtea mediterranea mk4.022116.01  
Schmidtea mediterranea mk4.007268.02   AMP deaminase 2
Schmidtea mediterranea mk4.025763.00  
Schmidtea mediterranea mk4.000649.05   Adenosine monophosphate deaminase 1
Schmidtea mediterranea mk4.016439.04   Adenosine monophosphate deaminase 1
Schmidtea mediterranea mk4.000135.03   AMP deaminase 2
Trypanosoma brucei gambiense Tbg972.11.17670   AMP deaminase, putative
Trypanosoma brucei gambiense Tbg972.9.3860   adenosine monophosphate deaminase, putative,AMP deaminase, putative
Trypanosoma brucei gambiense Tbg972.9.5600   AMP deaminase, putative
Trypanosoma brucei gambiense Tbg972.11.4470   AMP deaminase, putative
Trypanosoma brucei Tb927.9.7180   adenosine monophosphate deaminase, putative
Trypanosoma brucei Tb927.11.15750   AMP deaminase, putative
Trypanosoma brucei Tb927.9.9740   AMP deaminase, putative
Trypanosoma brucei Tb927.11.3850   AMP deaminase, putative
Trypanosoma congolense TcIL3000.11.3800   AMP deaminase, putative
Trypanosoma congolense TcIL3000_0_53780   adenosine monophosphate deaminase, putative
Trypanosoma congolense TcIL3000_9_3570   AMP deaminase, putative
Trypanosoma congolense TcIL3000_9_2410   adenosine monophosphate deaminase, putative
Trypanosoma cruzi TcCLB.506733.20   AMP deaminase, putative
Trypanosoma cruzi TcCLB.410589.10   AMP deaminase, putative
Trypanosoma cruzi TcCLB.511857.80   AMP deaminase, putative
Trypanosoma cruzi TcCLB.461927.9   adenosine monophosphate deaminase, putative
Trypanosoma cruzi TcCLB.506885.390   AMP deaminase, putative
Trypanosoma cruzi TcCLB.510729.10   AMP deaminase, putative
Trypanosoma cruzi TcCLB.508273.10   adenosine monophosphate deaminase-like protein, putative
Toxoplasma gondii TGME49_234280   AMP deaminase

Essentiality

Tb927.9.7180 has direct evidence of essentiality
Gene/Ortholog Organism Phenotype Source Study
Tb11.02.1340 Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (3 days) alsford
Tb11.02.1340 Trypanosoma brucei significant loss of fitness in bloodstream forms (6 days) alsford
Tb11.02.1340 Trypanosoma brucei no significant loss or gain of fitness in procyclic forms alsford
Tb11.02.1340 Trypanosoma brucei significant loss of fitness in differentiation of procyclic to bloodstream forms alsford
Tb09.211.1320 Trypanosoma brucei significant loss of fitness in bloodstream forms (3 days) alsford
Tb09.211.1320 Trypanosoma brucei significant loss of fitness in bloodstream forms (6 days) alsford
Tb09.211.1320 Trypanosoma brucei significant loss of fitness in procyclic forms alsford
Tb09.211.1320 Trypanosoma brucei no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms alsford
Tb09.160.5250 this record Trypanosoma brucei significant loss of fitness in bloodstream forms (3 days) alsford
Tb09.160.5250 this record Trypanosoma brucei significant loss of fitness in bloodstream forms (6 days) alsford
Tb09.160.5250 this record Trypanosoma brucei no significant loss or gain of fitness in procyclic forms alsford
Tb09.160.5250 this record Trypanosoma brucei no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms alsford
Tb11.01.7390 Trypanosoma brucei significant loss of fitness in bloodstream forms (3 days) alsford
Tb11.01.7390 Trypanosoma brucei significant loss of fitness in bloodstream forms (6 days) alsford
Tb11.01.7390 Trypanosoma brucei no significant loss or gain of fitness in procyclic forms alsford
Tb11.01.7390 Trypanosoma brucei significant loss of fitness in differentiation of procyclic to bloodstream forms alsford
CELE_C34F11.3 Caenorhabditis elegans larval arrest wormbase
CELE_C34F11.3 Caenorhabditis elegans slow growth wormbase
TGME49_234280 Toxoplasma gondii Probably essential sidik
Show/Hide essentiality data references
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.

Phenotypes and Validation (curated)

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Drugs/Inhibitors
growth (GO:0040007) lethal (sensu genetics) (PATO:0000718) single cell organism (CARO:0000064) bloodstream stage (PLO:0040) in vivo inhibition (TDR:00016) Trypanosoma brucei brucei 62653   120459  
Annotator: ts4@sanger.ac.uk. Comment: Drug: ADA inhibitors. . References: 16968221
cell proliferation (GO:0008283) decreased (PATO:0000468) bloodstream stage trypomastigotes (PLO:0027) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: decreased cell proliferation (significant loss of fitness) in bloodstream forms (stage 6 days). References: 21363968
cell proliferation (GO:0008283) normal (PATO:0000461) procyclic (PLO:0034) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: normal cell proliferation (no significant loss or gain of fitness) in differentiation of procyclic to bloodstream forms . References: 21363968

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.


Annotated validation

No validation data for this target

Associated compounds / Druggability

Druggability index (range: 0 to 1): 0.3


Known modulators for this target

Compound Source Reference
Curated by TDRTargets References
Curated by TDRTargets References

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Trypanosoma brucei AMP deaminase, putative Compounds References
Trypanosoma brucei AMP deaminase, putative Compounds References
Arabidopsis thaliana AMP deaminase Compounds References
Homo sapiens adenosine monophosphate deaminase 2 Compounds References
Trypanosoma brucei AMP deaminase, putative Compounds References
Oryctolagus cuniculus AMP deaminase 1 Compounds References
Homo sapiens adenosine monophosphate deaminase 1 Compounds References
Homo sapiens adenosine monophosphate deaminase 3 Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets

Obtained from network model

Ranking Plot


Putative Drugs List


Compound Raw Global Species
0.149 0.4545 1
0.0129 0.3103 0.7959
0.034 0.2584 0.6531
0.049 0.2864 1
0.0332985 0.299904 1
0.0319347 0.975237 1
0.3351 0.598 0.5
0.0129 0.8676 0.5
0.3172 0.7735 1
0.404 0.6089 1
0.117722 1 0.5
0.0304 0.6953 1
0.3617 0.7815 1
0.0335 0.4026 0.9694
0.2255 0.6734 1
0.0345 0.2544 0.2808
0.3033 0.814 1
0.0141 0.3021 1
0.3172 0.7654 0.5
0.0209 0.3215 1
0.4065 0.3379 0.4859
0.2581 0.8332 0.5
0.2441 0.4817 1
0.3172 0.7735 1
0.4387 0.5741 0.5
0.2172 0.4642 1
0.0333 0.4036 0.9713
0.1046 0.4805 0.5
0.1158 0.6004 0.5
0.5484 0.6326 0.5
0.0978 0.4712 1
0.5038 0.529 0.5
0.2505 0.4811 1
0.1904 0.512 0.5
0.3172 0.7735 1
0.2172 0.4642 1
0.0347 0.2558 0.2858
0.3901 0.7683 1
0.5729 0.6166 0.5
0.1949 0.5909 0.5
0.0055 0.2871 0.5
0.2569 0.4778 1
0.1391 0.2517 0.5
0.3389 0.6036 0.5
0.4218 0.6484 0.5
0.0465 0.5515 1
0.0442 0.4678 1
0.3513 0.8171 1
0.3617 0.7815 1
0.0319347 0.975237 1
0.01 0.8676 0.5
0.0117 0.3059 0.5
0.0332 1 1
0.0393 0.4787 1
0.252 0.4935 0.5
0.0117 0.3059 0.5
0.031 0.7112 1
0.0331 0.9369 1
0.3495 0.6989 1
0.1201 0.8855 0.5
0.4001 0.7758 1
0.0141 0.3021 1
0.0834 0.3212 1
0.1484 1 1
0.0055 0.2871 0.5
0.0086 0.3024 0.5
0.0292 0.3193 1
0.0129 0.872 0.5
0.0321883 0.291152 1
0.3495 0.6989 1
0.2707 0.5057 0.5
0.0373 0.8043 1
0.1942 0.699 1
0.1016 0.3468 1
0.2049 0.4751 1
0.0321883 0.291152 1
0.2125 0.474 1
0.0308 0.3662 0.5659
0.0332 0.4024 0.9641
0.0178 0.3027 1
0.3835 0.5906 1
0.445 0.5666 0.5
0.0129 0.8676 0.5
0.3835 0.5906 1
0.3859 0.538 0.5
0.0316364 0.274095 0.31074
0.0307 0.2721 0.8246
0.0335 0.4026 0.9694
0.1158 0.6004 0.5
0.0183 1 0.5
0.0088 0.28 1
0.2937 0.7168 1
0.0209 0.2909 1
0.0335 0.4047 0.6522
0.0151 0.2515 0.5
0.0088 0.28 1
0.01 0.8676 0.5
0.062 0.3351 1
0.216 0.9992 1
0.0261 0.3082 0.7126
0.0129 0.8676 0.5
0.0303 0.3685 0.879
0.0129 0.8676 0.5
0.2125 0.474 1
0.0349 0.2587 0.3712
0.062 0.3351 1
0.0347 0.2558 0.2858
0.3835 0.5906 1
0.2851 0.4789 0.5
0.3172 0.7735 1
0.149 0.4545 1
0.2586 0.87 1
0.0294 0.3125 0.5352
0.1642 0.4741 0.5
0.1198 0.4186 1
0.3617 0.7815 1
0.4742 0.7215 1
0.3786 0.759 1
0.0319 0.3502 0.9326
0.2174 0.9528 0.5
0.2586 0.87 1
0.1484 1 1
0.149 0.4545 1
0.3172 0.7735 1
0.0334 0.2556 0.9708
0.2386 0.6754 1
0.0129 0.8676 0.5
0.0117 0.3059 0.5
0.019 1 0.5
0.2707 0.5057 0.5
0.0345 0.2544 0.2808
0.0789 0.8676 0.5
0.0189 0.4781 1
0.0517 0.4787 0.5
0.0341 0.2558 0.9709
0.2838 0.4924 1
0.3669 0.7606 1
0.0294 0.3125 0.5352
0.1604 0.3507 0.5
0.031 0.366 0.894
0.2441 0.4817 1
0.466 0.7001 1
0.0117 0.3059 0.5
0.0445 0.2566 0.3124
0.2049 0.4751 1
0.0129 0.872 0.5
0.0332 0.388 0.9452
0.0271 0.2625 0.5
0.0312858 0.275507 1
0.4001 0.7758 1
0.0095 1 0.5
0.4001 0.7758 1
0.3835 0.5906 1
0.3865 0.7396 0.5
0.0234 0.2944 0.5
0.2125 0.474 1
0.2937 0.7168 1
0.0178 0.3163 0.5
0.0312 0.389 1
0.3851 0.5923 0.5
0.2505 0.4811 1
0.2441 0.4817 1
0.1744 0.5061 1
0.4387 0.5741 0.5
0.0333 0.4039 0.973
0.0129 0.8676 0.5
0.012 0.2957 1
0.4239 0.6326 0.5
0.3495 0.6989 1
0.0309 0.3682 0.3845
0.5033 0.5287 0.5
0.0319347 0.975237 1
0.3401 0.4966 0.5
0.3513 0.8171 1
0.0234 0.2944 0.5
0.0332985 0.299904 1
0.137 1 0.5
0.4867 0.2964 0.5
0.117722 1 0.5
0.029 0.2905 1
0.0306 0.8676 0.5
0.3457 0.4983 0.5
0.2049 0.4751 1
0.0208 0.8676 0.5
0.5038 0.529 0.5
0.3786 0.759 1
0.0209 0.2909 1
0.0312 0.3897 1
0.3835 0.5906 1
0.374 0.5908 1
0.2505 0.4811 1
0.0102 0.6452 0.619
0.0349 0.2587 0.3737
0.0978 0.8676 0.5
0.3158 0.7548 1
0.3513 0.8171 1
0.0129 0.3844 1
0.0064 0.2566 0.813
0.1241 0.5116 0.5
0.1016 0.3468 1
0.3158 0.7548 1
0.1391 0.2517 0.5
0.4708 0.6191 0.5
0.0333 0.4039 0.973
0.3533 0.7788 0.5
0.1123 0.409 0.5
0.0338 0.4047 0.6526
0.3034 0.8443 0.5
0.0129 0.8676 0.5
0.4193 0.6056 0.5
0.349 0.3937 0.5
0.2441 0.4817 1
0.1015 0.5532 0.5
0.0223 0.582 0.5
0.1061 0.9344 1
0.2019 0.4008 0.5
0.2172 0.4642 1
0.0803 0.415 0.5
0.0122 0.2564 0.8202
0.0831 0.3349 0.5
0.2706 0.4411 0.5
0.0323 0.3598 1
0.0129 0.8676 0.5
0.0129 0.8676 0.5
0.0055 0.2871 0.5
0.0129 0.8676 0.5
0.3378 0.4617 0.5
0.0351 0.2618 0.4359
0.0129 0.8676 0.5
0.0312 0.3687 0.8354
0.0345 0.2563 0.2812
0.0333 1 1
0.0312 0.3897 1
0.3158 0.7548 1
0.1977 0.4744 1
0.0101 0.6059 0.578
0.1721 0.3297 1
0.0352 0.2547 0.2894
0.117722 1 0.5
0.2679 0.4793 0.5
0.4218 0.6484 0.5
0.3617 0.7815 1
0.0129 0.258 0.5
0.0055 0.2871 0.5
0.0188 0.6301 1
0.1546 0.4495 1
0.1744 0.5061 1
0.0345 0.2567 0.2822
0.4742 0.7215 1
0.031 0.3817 0.9029
0.0307 0.2721 0.8246
0.3669 0.7606 1
0.02 0.5775 0.5
0.4064 0.5989 0.5
0.2441 0.4817 1
0.4061 0.5635 1
0.3901 0.7683 1
0.117722 1 0.5
0.3814 0.7223 1
0.0333 0.4786 1
0.3495 0.6989 1
0.3172 0.7735 1
0.0406 0.2821 1
0.0055 0.2892 0.5
0.4742 0.7215 1
0.0236 0.3132 1
0.0202 0.8676 0.5
0.1222 0.3923 1
0.0129 0.872 0.5
0.2125 0.474 1
0.0337 0.3879 1
0.4218 0.6484 0.5
0.3835 0.5906 1
0.3304 0.6245 1
0.2172 0.4642 1
0.0237 0.4563 0.5
0.3495 0.6989 1
0.3172 0.7735 1
0.2552 0.6392 1
0.4708 0.6191 0.5

Assayability

Assay information

  • Assay for 5'-Adenylic Acid Deaminase (3.5.4.6 ) Sigma-Aldrich
  • Automatic link to known assays based on EC numbers.

Reagent availability

No reagent availability information for this target.

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

User comments

No user comments are available for this gene. Log in to add comments, or register.

Enter your comment

User ()
Gene identifier Tb927.9.7180 (Trypanosoma brucei), adenosine monophosphate deaminase, putative
Title for this comment
Comment