Detailed view for Tb927.9.12700

Basic information

TDR Targets ID: 17748
Trypanosoma brucei, phospholipase A1, putative
Source Database / ID:  TriTrypDB  GeneDB

pI: 8.0054 | Length (AA): 447 | MW (Da): 49912 | Paralog Number: 0

Signal peptide: Y | GPI Anchor: | Predicted trans-membrane segments: 2

Druggability Group : DG4

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF03403   Platelet-activating factor acetylhydrolase, isoform II

Gene Ontology

Mouse over links to read term descriptions.
GO:0008150   biological_process  
GO:0005576   extracellular region  
GO:0004623   phospholipase A2 activity  
GO:0003847   1-alkyl-2-acetylglycerophosphocholine esterase activity  
GO:0016042   lipid catabolic process  

Structural information

Modbase 3D models:

There are 4 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
83 442 3d59 (A) 56 397 18.00 0 1 0.918269 -0.13
88 440 3d59 (A) 61 395 21.00 0 1 0.907509 -0.15
127 258 3c10 (B) 768 901 35.00 0.72 0.39 0.196302 1.51
264 369 2qs9 (B) 49 155 17.00 0 0.5 0.408936 -0.37

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

Upregulation Percent Ranking Stage Dataset
Upper 80-100% percentile Bloodstream Form. Siegel TN
Upregulation Percent Ranking Stage Dataset
Upper 60-80% percentile Procyclic. Siegel TN
Show/Hide expression data references
  • Siegel TN Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites.

Orthologs

Ortholog group members (OG5_129351)

Species Accession Gene Product
Brugia malayi Bm1_04790   Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein
Caenorhabditis elegans CELE_W03G9.6   Protein PAF-1
Caenorhabditis elegans CELE_C52B9.7   Protein PAF-2, isoform B
Homo sapiens ENSG00000146070   phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
Homo sapiens ENSG00000158006   platelet-activating factor acetylhydrolase 2, 40kDa
Leishmania braziliensis LbrM.34.2930   phospholipase A1, putative
Leishmania donovani LdBPK_353070.1   phospholipase A2-like protein, putative
Leishmania infantum LinJ.35.3070   phospholipase A1, putative
Leishmania major LmjF.35.3020   phospholipase A1, putative
Leishmania mexicana LmxM.34.3020   phospholipase A2-like protein, putative
Loa Loa (eye worm) LOAG_02837   platelet-activating factor acetylhydrolase
Mus musculus ENSMUSG00000023913   phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
Mus musculus ENSMUSG00000037366   platelet-activating factor acetylhydrolase 2
Onchocerca volvulus OVOC12784  
Onchocerca volvulus OVOC2536  
Onchocerca volvulus OVOC1719  
Trypanosoma brucei gambiense Tbg972.9.7760   phospholipase A2-like protein, putative
Trypanosoma brucei Tb927.9.12700   phospholipase A1, putative
Trypanosoma congolense TcIL3000_0_00740   phospholipase A1, putative
Trypanosoma cruzi TcCLB.510659.250   phospholipase A1, putative
Trypanosoma cruzi TcCLB.510743.60   phospholipase A1, putative

Essentiality

Tb927.9.12700 has direct evidence of essentiality
Gene/Ortholog Organism Phenotype Source Study
Tb09.211.3650 this record Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (3 days) alsford
Tb09.211.3650 this record Trypanosoma brucei significant gain of fitness in bloodstream forms (6 days) alsford
Tb09.211.3650 this record Trypanosoma brucei significant loss of fitness in procyclic forms alsford
Tb09.211.3650 this record Trypanosoma brucei no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms alsford
CELE_C52B9.7 Caenorhabditis elegans embryonic lethal wormbase
CELE_C52B9.7 Caenorhabditis elegans larval lethal wormbase
Show/Hide essentiality data references
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.

Phenotypes and Validation (curated)

Annotated phenotypes:

Affected Entity Phenotypic quality Occurs in Occurs at Evidence Observed in Drugs/Inhibitors
cell proliferation (GO:0008283) normal (PATO:0000461) bloodstream stage trypomastigotes (PLO:0027) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: normal cell proliferation (no significant loss or gain of fitness) in bloodstream forms (stage 3 days). References: 21363968
cell proliferation (GO:0008283) increased (PATO:0000470) bloodstream stage trypomastigotes (PLO:0027) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: increased cell proliferation (significant gain of fitness) in bloodstream forms (stage 6 days). References: 21363968
cell proliferation (GO:0008283) decreased (PATO:0000468) procyclic (PLO:0034) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: decreased cell proliferation (significant loss of fitness) in procyclic forms . References: 21363968
cell proliferation (GO:0008283) normal (PATO:0000461) procyclic (PLO:0034) inferred from RNAi experiment (ECO:0000019) No drug identifiers listed for this gene.
Annotator: fernan@iib.unsam.edu.ar. Comment: normal cell proliferation (no significant loss or gain of fitness) in differentiation of procyclic to bloodstream forms . References: 21363968

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Druggability index (range: 0 to 1): 0.6

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Mus musculus platelet-activating factor acetylhydrolase 2 Compounds References
Sus scrofa Group VII phospholipase A2 Compounds References
Homo sapiens phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Compounds References
Mus musculus phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model

Ranking Plot

Putative Drugs List

Compound Raw Global Species
0.3181 1 1
0.0326 0.2588 0.2588
0.0682 0.6897 1
0.0402 0.4497 1
1.07 0.3419 1
0.0328 0.2858 1
0.0706 1 1
0.0402 1 1
0.0402 0.5102 1
0.0402 0.5 0.5
0.8061 1 1
0.068 0.3203 1
0.0682 0.5085 1
0.07 0.8074 1
0.0324 0.2758 1
0.4498 0.411 1
0.27 1 1
0.2783 1 1
1.8228 1 1
0.1886 0.562 1
0.4006 1 1
0.0402 0.5 0.5
0.7381 1 0.5
1.4408 1 1
0.3245 1 0.5
0.0364 0.3325 1
2.1726 1 1
0.1076 0.406 1
0.034 0.4089 1
0.0325 0.3926 1
0.0763 1 1
0.0324 0.6079 1
0.0402 1 1
0.4498 0.411 1
0.0732 0.4098 0.9357
0.0686 0.4087 1
0.0402 0.5102 0.5
0.0358 0.4041 1
0.0402 0.5 0.5
0.0348 0.6446 1
0.0757 1 1
0.0732 0.504 1
0.0685 0.5936 1
0.0324 0.3258 1
1.9708 1 1
0.8093 1 1
0.0659 0.4018 1
0.0358 0.4023 1
0.0327 0.3983 1
0.0402 0.4692 0.5035
0.0343 0.5424 1
0.1951 1 1
0.0402 0.3076 1
0.0402 1 0.5
0.1096 1 0.5
0.3412 0.5 0.5
0.3675 1 1
1.7929 1 1
0.2589 1 1
2.1545 1 1
0.0321 0.2664 0.5
2.1972 1 1
0.121317 1 1
0.8756 1 1
0.0357 0.4879 0.5
0.5128 1 1
0.233 1 1
0.3698 1 1
0.0743 0.455 0.5
0.0346 0.5997 1
1.7822 1 1
0.6992 1 1
0.0327 0.2552 1
0.0327 0.3541 1
0.0781 0.795 1
0.0402 0.5213 0.7569
0.0402 0.4978 1
0.2999 0.6755 1
0.0348 0.5 0.5
0.2105 1 0.5
0.4114 1 0.5
0.0402 1 1
2.043 1 1
0.3688 1 1
0.0329 0.5687 1
0.1055 0.5855 1
0.0657 0.3795 0.9161
0.7381 1 1
0.0675 0.5968 1
0.0696 0.4202 1
0.0389 0.2894 0.3453
0.0335 0.4516 1
0.0331 0.2514 1
0.0709 1 0.5
0.0336 0.4701 1
0.0402 1 1
0.2346 1 1
1.7929 1 1
0.0335 0.3859 1
0.0331 0.5177 1
0.0343 0.3948 1
0.3534 1 0.5
0.1036 0.3113 1
0.0342 0.5206 1
0.6979 1 1
0.0737 0.4131 1
0.1004 0.2984 0.9131
0.4172 1 1
1.785 1 1
0.3746 1 1
0.0343 0.3453 1
0.0394 1 1
0.0667 0.3286 1
0.0467382 0.689036 1
0.1485 1 0.5
0.3181 1 1
0.1155 0.4668 1
0.0402 0.3048 1
0.0659 0.4004 1
0.0402 0.9996 1
0.099 1 0.5
0.2247 1 0.5
0.0326 0.3319 1
0.0402 1 0.5
0.6513 1 1
0.2689 0.8015 1
2.0531 1 1
0.3521 1 1
0.0357 0.4144 0.7015
0.0324 0.5102 1
0.1155 0.4668 1
0.8836 1 0.5
0.0763 0.2946 0.2943
0.0666 0.5938 1
0.1479 1 1
0.0402 1 1
0.0325 0.6474 1
0.1319 0.4693 1
0.067 0.2735 0.7115
0.0326 0.5 0.5
2.0782 1 1
1.433 1 1
0.0733 0.5897 1
0.1944 1 1
0.0709 0.5934 1
0.27 1 1
1.8759 1 1
0.0327 0.3726 0.421
0.0329 1 0.5
0.0326 1 0.5
0.2999 0.6755 1
0.0667 0.5503 1
0.0699 0.3922 0.4725
0.035 0.531 1
0.1739 0.4133 1
0.0402 0.5 0.5
0.8093 1 1
1.7424 1 1
0.0329 0.5754 1
0.2112 0.4969 1
0.7762 1 1
0.0335 0.2626 0.2626
0.7868 1 1
0.0678 0.2615 0.8067
0.4428 1 1
0.0357 0.5405 1
0.0367 0.3625 1
0.27 1 1
0.2122 1 0.5
0.0324 0.5497 1
0.0402 0.5789 1
0.1036 0.3113 1
0.067 0.2735 0.7115
0.071 0.3525 0.9481
0.1739 0.4133 1
0.0402 0.4312 1
0.1034 0.2871 0.5
1.6136 0.8001 1
0.1033 1 1
0.0363 0.3545 0.5
0.0335 0.7551 1
0.2642 1 1
0.1754 1 1
0.3991 1 0.5
0.0722 1 1
0.0709 0.5934 1
0.0402 1 0.5
0.0402 0.4878 1
0.0659 0.4093 1
0.111 0.5168 1
0.0402 0.5 0.5
0.0402 0.5213 0.7569
0.0402 0.5654 1
0.6992 1 1
0.2351 1 0.5
0.0325 0.6435 1
0.0666 1 1
0.0354 0.4285 0.5
0.0987 1 0.5
0.875 1 0.5
0.5068 1 1
0.1523 1 0.5
0.3204 1 0.5
0.0693 0.2708 0.7036
1.6136 0.8001 1
0.0389 0.2894 0.3453
0.409 1 0.5
0.1004 0.2984 0.9131
0.1889 0.4262 1
0.0714 0.4138 1
0.4869 1 1
0.0331 0.4748 1
1.2834 1 1
0.0354 1 0.5
0.0743 0.455 0.5
0.1986 1 0.5
0.0402 1 0.5
0.0659 0.4116 1
0.1052 0.3381 1
0.0402 1 1
1.6136 0.8001 1
0.4305 1 1
0.9587 1 1
0.0328 0.5755 1
0.0361 0.2502 0.2493
0.277 1 1
0.0321 0.397 0.4854
0.2261 1 1
0.2824 1 0.5
0.4498 0.411 1
1.3794 1 1
1.0065 0.2708 1
0.2386 0.9976 1
0.0998 1 1
0.0402 0.4735 1
0.3099 1 1
0.1479 1 1
0.0661 0.5983 1
0.0402 0.5 0.5
0.1739 0.4133 1
0.0357 0.4105 0.6766
0.1676 0.4993 1
1.0278 1 1
0.0402 1 0.5
0.0697 1 1
0.0402 0.3076 1
0.0332 0.49 1
0.0402 0.478 0
0.034 0.4086 1
0.3285 1 0.5
0.2005 1 1
0.4123 1 1
0.0402 0.4393 1
0.1958 1 1
0.1986 1 0.5
0.0402 0.5 0.5
0.0681 0.587 0.8883
0.861 1 1
2.1726 1 1
0.7129 1 0.5
0.2638 1 1
0.0803 0.3897 1
0.1004 0.2984 0.9131
0.0402 0.2625 0.5
0.0321 0.4442 0.5
0.4172 1 1
0.0747 0.4222 0.9986
0.8827 1 0.5
0.2199 1 1
0.0402 1 1
0.036 0.3266 1
0.0321 0.3191 1
0.4453 1 0.5
0.0328 0.3983 0.4654
0.0324 0.5102 0.5
0.0325 0.6021 1
0.1124 1 0.5
0.9587 1 1
2.2841 1 1
0.034 0.4086 1
0.0402 0.5 0.5
0.1326 1 1
0.0402 0.5 0.5
0.192 1 1
0.0681 0.2606 0.4076
0.1079 0.5393 1
0.1055 0.3346 1
0.0715 0.5887 0.6278
0.2999 0.6755 1
0.0402 0.4066 1
0.0402 1 0.5
0.0402 1 1
1.9426 1 1
0.8807 1 1
0.0352 0.3921 1
1.7239 1 1
0.901 1 1
0.0402 0.2507 1
1.3794 1 1
0.7121 1 0.5
0.0402 0.5395 1
0.1109 0.6763 1
0.2432 1 0.5
0.0402 0.5 0.5
0.1367 1 1
1.7239 1 1
0.1326 1 1
0.0357 0.4879 0.5
0.0402 0.4 1
0.1126 1 1
0.0358 0.4023 1
0.9587 1 1
0.0326 0.6107 0.5
1 0.2735 1
0.0678 0.5524 0.9895
2.1238 1 1
0.3313 1 0.5
0.0402 0.4697 0.5
0.0328 0.2692 1
2.0466 1 1
1.0065 0.2708 1
0.0402 0.2694 1
0.0402 0.3188 1
0.2999 0.6755 1
0.1109 0.6763 1
1.9708 1 1
0.0344 0.4442 1
0.0288 0.3319 0.5
0.4002 1 1
0.0322 0.3883 1
2.4357 1 1
0.4498 0.411 1
0.0402 0.3216 1
0.4256 1 0.5
0.2482 1 1
0.4102 1 0.5
0.0355 0.5832 1
0.0329 0.39 1
0.0743 0.455 0.5
0.0359 0.5102 0.5
0.0321 0.2756 0.2742
0.7381 1 1
0.0402 1 1
1.0065 0.2708 1
0.1055 0.5855 1
0.2689 0.8015 1
0.0337 0.4692 1
0.0803 1 1
0.2447 0.8535 1
0.1328 1 1
0.369 1 1
0.0698 0.3844 0.3842
0.0338 1 1
0.036 0.3266 1
0.1365 0.8084 1
0.0402 0.4611 1
0.2999 0.6755 1
0.0402 0.5 0.5
0.0402 0.5069 1
0.0402 1 1
0.0371 0.2904 0.2894
0.0402 0.5103 1
0.0651 0.5512 1
0.0331 0.5027 1
0.3219 0.7652 1
0.2426 0.5804 1
0.0652 0.5084 1
0.0662 0.5498 1
0.0328 0.6536 0.5
0.0345 0.403 1
0.1415 1 0.5
0.0672 0.3982 1
0.067 0.2735 0.7115
0.034 0.4089 1
0.3698 1 1
0.1958 1 1
0.0402 0.5 0.5
0.1717 0.6277 1
0.034 0.4086 1
1.7166 1 1
0.0354 0.2501 0.2491
0.5568 1 1
0.9587 1 1
0.0402 0.4671 0.5
0.0364 0.3289 1
0.1937 1 1
0.0402 0.7477 1
0.0331 0.5027 1
0.0402 0.4643 0.5
0.8198 1 0.5
0.0402 0.5 0.5
0.0327 0.3698 0.424
0.0335 0.7551 1
0.2266 0.57 1
0.0659 0.4116 1
0.2743 0.8869 1
0.6484 1 1
0.0326 0.3327 1
0.6447 1 1
0.0402 1 0.5
0.1792 1 1
0.4233 1 0.5
0.2792 1 0.5
0.9025 1 1
0.5404 0.8267 1
0.1809 1 1
1.6763 1 1
0.0538 0.3619 1
0.4483 1 0.5
0.0402 0.5213 0.7569
0.4172 1 1
0.2328 1 0.5
0.2426 0.5804 1
0.0638 1 1
0.0402 1 0.5
0.0321 0.4186 0.5
0.0337 0.5185 1
0.2427 0.7105 1
0.1847 1 1
0.071 0.3525 0.9481
0.0402 0.7855 1
0.0324 0.4304 1
0.5431 1 1
0.0321 0.2756 0.2742
0.274 0.6579 0.6579
0.2743 0.8869 1
0.344 1 1
2.0476 1 1
0.0714 0.3931 0.9104
0.0737 0.4131 1
0.2293 1 0.5
0.0336 0.4174 1
0.0351 0.4386 1
0.0717 1 1
0.4123 1 1
0.0325 0.3939 1
0.0402 0.5 0.5
0.0402 0.5 0.5
0.033 0.6382 1
0.0402 0.5 0.5
1.3514 1 1
0.0402 0.4515 1
0.0402 0.811 1
0.0402 0.8576 1
0.0712 0.4926 1
0.7501 1 0.5
0.0362 0.3158 0.6637
0.1488 1 1
1.7929 1 1
0.0402 0.5 0.5
0.1036 0.3113 1
1.8759 1 1
0.0326 0.6404 0.5
2.4357 1 1
0.0336 0.4107 1
0.0659 0.4116 1
0.0673 1 0.5
0.3083 1 0.5
0.0696 0.2622 0.4567
2.1414 1 1
0.3204 1 0.5
0.7121 1 0.5
1.4408 1 1
0.1847 1 1
0.2999 0.6755 1
0.5431 1 1
0.1739 0.4133 1
0.3502 1 1
0.0659 0.3907 1
0.1717 0.6277 1
0.1754 1 0.5
0.0657 0.5957 1
0.4297 1 1
0.2792 1 0.5
1.9708 1 1
0.1818 0.2795 1
0.0402 0.4609 0.5
0.0402 0.6741 1
0.0402 0.5551 1
0.0331 0.4758 0.7422
2.4357 1 1
0.1557 1 1
0.0402 0.478 0
0.4277 1 0.5
0.0324 0.538 1
1.6784 1 1
0.0717 1 1
0.0329 1 0.5
0.2358 0.991 1
0.0402 0.998 1
0.1944 1 0.5
0.0669 0.5943 1
0.0336 0.4113 1
0.3181 1 1
0.0402 0.5 0.5
0.0667 0.411 1
0.0332 0.5102 0.5
0.0344 0.3143 1
0.2743 0.8869 1
2.4357 1 1
0.0338 1 1
0.2321 1 1
0.0323 0.3936 1
0.2229 1 1
0.0402 1 1
0.3132 1 0.5
0.0715 0.5933 1
0.0402 0.998 1
0.0321 0.281 0.2806
0.3797 1 1
1.07 0.3419 1
0.2043 1 0.5
0.1137 1 1
0.0402 0.6854 1
0.0321 0.4303 0.5
0.066 1 1
0.0339 0.32 0.3191
0.0402 0.4063 1
0.0715 0.5887 0.6278
0.1926 0.4553 1
0.0324 0.4722 1
0.2743 0.8869 1
0.0323 1 1
0.0696 0.4202 1
0.5068 1 1
0.3698 1 1
0.0676 0.3225 1
0.0665 0.4442 1
0.2423 1 1
0.4123 1 1
0.0348 0.5218 1
0.2544 1 1
0.0695 0.8699 1
0.1675 0.3448 1
0.0712 0.8806 1
0.2146 0.8357 0.8354
0.0659 0.4116 1
0.0323 0.5488 1
0.9025 1 1
0.0323 0.3224 0.5331
0.1016 1 1
0.1673 1 0.5
0.2063 1 0.5
0.0402 0.4534 1
0.0324 0.6079 1
0.0402 1 1
0.0345 0.4755 0.7694
0.0402 0.5 0.5
1.7239 1 1
0.033 0.6228 0.5
0.0659 0.4116 1
0.2112 0.4969 1
0.5349 1 1
1.8759 1 1
0.4471 0.3999 1
0.0336 0.3497 1
0.0402 1 1
0.0677 1 0.5
0.5062 1 0.5
0.2358 0.991 1
1.5712 1 1
0.0402 1 1
0.0402 1 1
2.5109 1 1
0.1863 1 0.5
0.202 1 0.5
0.2783 1 1
0.0605 0.2581 1
2.1972 1 1
0.3261 1 1
0.0321 0.3515 1
0.3156 1 0.5
0.1109 0.6763 1
0.4408 1 1
0.0715 0.5887 0.6278
1.785 1 1
0.1036 0.3113 1
0.0329 0.4698 1
0.2002 1 0.5
0.4498 0.411 1
0.9025 1 1
0.1739 0.4133 1
0.226 1 0.5
0.0717 1 1
0.0402 0.5435 1
0.0402 1 1
0.0323 0.3936 1
0.1675 0.3448 1
0.0402 0.4888 1
0.1058 1 0.5
0.0344 0.3924 0.7706
0.0402 1 0.5
0.0362 0.4452 1
0.1415 1 0.5
1.7949 1 1
0.4471 0.3999 1
0.036 0.4645 1
0.1109 0.6763 1
0.2002 1 1
0.0402 0.5 0.5
0.1324 0.7786 0.5
0.1685 1 1
1.7239 1 1
0.0659 0.5934 1
0.1141 1 1
0.3312 0.6682 1
0.1352 1 1
0.0402 0.5465 1
0.0335 0.5752 1
0.0377 1 1
0.1415 1 0.5
0.0402 1 1
0.0402 0.998 1
0.0335 0.3913 1
0.0676 1 1
0.0721 1 1
0.0338 1 1
0.3181 1 1
0.0337 0.2584 0.2497
0.5349 1 1
1.845 1 1
0.2712 1 0.5
0.1036 0.3113 1
0.6992 1 1
0.0698 0.3923 0.8981
0.0327 0.2648 1
0.0402 0.5 0.5
0.1065 1 1
0.9587 1 1
0.0733 0.4194 1
0.1531 1 1
0.0402 1 0.5
0.0321 0.281 0.2806
0.0402 1 1
0.1036 0.3113 1
1.07 0.3419 1
2.0407 1 1
0.0314 1 1
1.845 1 1
0.0646 0.5627 0.5
0.1944 1 0.5
0.0402 1 0.5
0.0659 0.4116 1
0.0677 1 0.5
0.0402 0.7929 1
0.0335 0.2591 1
0.4097 1 1
0.0707 1 1
0.0367 0.5241 1
0.2743 0.8869 1
0.0323 0.5488 1
0.0358 0.2679 1
0.1739 0.4133 1
0.0747 0.4222 0.9986
0.0733 1 0.5
0.0323 0.3915 1
0.0323 0.5488 1
0.0402 1 1
0.0704 1 0.5
0.067 0.2735 0.7115
0.0712 0.3058 0.8303
1.661 1 1
0.0728 0.8717 1
0.1013 1 0.5
0.0982 0.4005 1
0.2544 1 1
0.036 0.4493 1
0.0331 0.4104 0.4146
0.0402 0.2507 1
0.0402 0.5089 1
0.0383 0.2646 0.2637
0.27 1 1
0.1787 1 0.5
0.0402 0.5 0.5
0.5349 1 1
0.1034 0.2871 0.5
0.0402 0.3595 1
0.0402 0.5213 0.7569
0.1792 1 1
0.0402 0.5 0.5
0.1016 1 0.5
0.0339 0.5137 1
0.1109 0.6763 1
0.4483 1 1
0.4498 0.411 1
0.0676 0.2945 0.8852
1.8771 1 1
0.0402 1 0.5
0.0763 1 0.5
0.7381 1 1
0.0342 0.5206 1
0.4471 0.3999 1
0.1831 1 0.5
0.2426 0.5804 1
1.8489 1 1
0.0402 0.5 0.5
0.0329 0.5786 1
0.3563 1 1
0.0402 1 1
0.0336 0.628 0.5
0.0343 0.4076 0.7743
0.2999 0.6755 1
1.7397 1 1
0.0323 0.5474 1
2.4357 1 1
0.0402 0.7968 1
0.0402 0.5 0.5
0.073 0.5916 1
0.3707 1 0.5
0.3479 1 0.5
0.0745 1 0.5
0.0402 1 1
0.0402 1 1
0.1357 1 1
0.0676 1 1
0.0324 0.4584 1
0.1034 0.2871 0.5
0.1739 0.4133 1
0.0402 0.3295 1
0.4341 1 0.5
0.036 0.3334 1
0.112 0.5614 1
0.0678 0.2726 0.9101
0.0402 0.5 0.5
0.1036 0.3113 1
0.0691 0.5944 0.9992
0.0672 0.5969 1
1.7356 1 1
1.5445 1 1
0.9629 1 1
0.0402 1 1
0.0322 1 0.5
0.0402 1 0.5
0.0324 0.4906 1
0.8528 1 0.5
1.1427 1 1
0.0362 0.3156 0.6628
0.0402 1 1
0.0402 0.5 0.5
0.1022 1 1
0.4123 1 1
0.2201 1 1
0.4508 1 0.5
0.1479 1 0.5
0.0352 0.4693 1
1.2319 1 1
0.901 1 1
0.4498 0.411 1
0.0402 0.5 0.5
0.0402 1 1
0.4172 1 1
0.774504 1 1
0.0659 0.4116 1
2.1726 1 1
0.0683 0.5928 1
0.0402 0.5 0.5
0.112 0.5614 1
0.0402 0.3892 0.5
0.0368 0.3005 0.2994
0.0402 1 0.5
0.0402 0.5 0.5
0.0695 0.8699 1
0.2792 1 0.5
0.941 1 0.5
0.0402 0.998 1
0.2253 1 0.5
0.0402 1 0.5
0.3984 1 1
0.2229 1 1
0.1818 0.2795 1
0.5046 1 1
0.4498 0.411 1
0.0402 0.4381 1
0.6447 1 1
0.034 0.4086 1
0.8807 1 1
0.3698 1 1
0.0288 0.281 1
0.6757 1 1
0.0334 0.3951 1
2.0187 1 1
0.0365 0.413 0.7022
0.0671 0.3838 1
0.0402 0.4379 1
1.0325 1 1
0.0993 1 1
0.5068 1 1
0.0337 0.5185 1
0.0659 0.4116 1
0.3035 1 1
0.8061 1 1
0.0344 0.3143 1
0.9587 1 1
0.0402 0.4805 1
1.6136 0.8001 1
0.3181 1 1
0.4498 0.411 1
0.033 0.6165 1
1.2347 1 1
0.0331 0.4303 0.5
2.0327 1 1
0.1833 1 1
0.0129744 0.5 0.5
0.0337 0.4692 1
0.1144 0.6033 1
0.0751 1 1
0.0324 0.3746 1
0.0402 0.4609 0.5
0.0683 0.4035 0.4613
0.0678 0.5937 0.9316
0.8807 1 0.5
0.0402 1 0.5
0.0324 0.2758 1
1.1277 1 1
0.3792 1 0.5
1.5325 1 1
0.1109 0.6763 1
0.4083 1 0.5
0.1886 0.562 1
0.0704 1 0.5
0.1365 0.8084 1
0.4758 1 0.5
0.9338 1 0.5
0.067 0.2735 0.7115
0.0694 0.6232 1
0.0657 0.3795 0.9161
0.4869 1 1
0.0715 0.5933 1
0.1183 1 0.5
0.0332 0.4771 1
0.408657 0.802218 1
0.9587 1 1
0.0321 0.2873 1
0.3099 1 1
0.0325 0.5417 1
0.0721 1 1
0.0402 1 0.5
0.0402 1 1
1.5683 1 1
0.0402 1 1
0.1806 1 0.5
0.5431 1 1
0.41 1 0.5
0.7129 1 1
0.0321 0.3116 1
0.1521 1 1
0.2743 0.8869 1
0.0367 0.2507 0.2507
0.0402 0.5 0.5
0.1401 1 0.5
0.0714 0.3033 0.5142
0.0775 0.895 1
0.0651 0.5512 1
0.0698 0.3923 0.8981
0.3961 1 1
1.6612 1 1
0.901 1 1
0.4965 1 1
0.0699 0.3922 0.4725
0.0329 1 0.5
0.1082 1 1
0.0402 0.5 0.5
0.344 1 1
0.0402 0.4493 0.8714
0.0323 1 0.5
0.5443 1 1
0.0803 0.5 0.5
0.0328 0.3891 0.6485
0.0402 0.3595 1
0.1977 0.7773 1
0.0714 0.3033 0.5142
0.0402 0.5 0.5
0.0402 0.6692 1
2.4357 1 1
1.6713 1 1
0.3077 1 1
0.0321 0.2873 1
0.0698 0.5945 1
0.0694 0.5102 0.5
1.303 1 1
0.1523 1 1
0.0344 0.3143 1
0.0402 0.5102 0.5
0.2255 1 0.5
0.8807 1 1
0.0129744 0.5 0.5
0.4498 0.411 1
0.4094 1 0.5
0.0402 0.2875 0.2875
0.111 0.5168 1
1.07 0.3419 1
0.3615 1 0.5
0.1951 1 1
0.4811 1 1
0.0682 0.3819 1
0.0402 0.5763 1
0.0324 0.538 1
0.8838 1 0.5
0.9057 1 1
0.2758 1 0.5
0.2447 0.8535 1
0.8402 1 1
0.1563 1 0.5
0.0335 0.2763 1
0.7153 1 1
0.0379 0.2504 0.2497
0.3822 1 1
0.0324 0.4703 0.5493
0.036 0.3334 1
1.8347 1 1
0.0335 0.4591 1
0.0402 0.5848 1

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

1 literature reference was collected for this gene.

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Gene identifier Tb927.9.12700 (Trypanosoma brucei), phospholipase A1, putative
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