Detailed view for LmjF.04.1160

Basic information

TDR Targets ID: 20817
Leishmania major,
Source Database / ID:  TriTrypDB  GeneDB

pI: 8.8332 | Length (AA): 351 | MW (Da): 38826 | Paralog Number: 0

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG3

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00316   Fructose-1-6-bisphosphatase, N-terminal domain

Gene Ontology

Mouse over links to read term descriptions.
GO:0042132   fructose-bisphosphatase activity  
GO:0016791   phosphoric monoester hydrolase activity  
GO:0042578   phosphoric ester hydrolase activity  
GO:0005975   carbohydrate metabolic process  

Structural information

Modbase 3D models:

There are 5 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
10 335 1dcu (A) 19 356 45.00 0 1 1.6 -1.76
7 340 5et6 (A) 8 336 41.00 0 1 1.49847 -1.05
10 334 5iz1 (A) 90 423 47.00 0 1 1.50473 -0.73
10 339 1bk4 (A) 11 335 46.00 0 1 1.50307 -1.01
11 329 2f3b (A) 12 325 46.00 0 1 1.52363 -1.06

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

PDB tag
  • 5OEY:
  • Resolution Method # Atoms # Residues Dep. Date Pub. Date Mod. Date
PDB tag
  • 5OEZ:
  • Resolution Method # Atoms # Residues Dep. Date Pub. Date Mod. Date
PDB tag
  • 5OFU:
  • Resolution Method # Atoms # Residues Dep. Date Pub. Date Mod. Date

Expression

Upregulation Percent Ranking Stage Dataset
Upper 80-100% percentile amastigotes, metacyclic. Fernandes MC
Show/Hide expression data references
  • Fernandes MC Dual Transcriptome Profiling of Leishmania-Infected Human Macrophages Reveals Distinct Reprogramming Signatures.

Orthologs

Ortholog group members (OG5_127400)

Species Accession Gene Product
Arabidopsis thaliana AT1G43670   fructose-1,6-bisphosphatase
Arabidopsis thaliana AT3G54050   fructose-1,6-bisphosphatase
Brugia malayi Bm1_37105   fructose-1,6-bisphosphatase
Candida albicans CaO19.6178   similar to S. cerevisiae FBP1 (YLR377C) Fructose-1,6-bisphosphatase
Caenorhabditis elegans CELE_K07A3.1   Protein FBP-1
Dictyostelium discoideum DDB_G0270836   D-fructose-1,6-bisphosphate 1-phosphohydrolase
Drosophila melanogaster Dmel_CG31692   fructose-1,6-bisphosphatase
Escherichia coli b4232   fructose-1,6-bisphosphatase I
Echinococcus granulosus EgrG_000261600   fructose 16 bisphosphatase 1
Echinococcus multilocularis EmuJ_000261600   fructose 1,6 bisphosphatase 1
Homo sapiens ENSG00000130957   fructose-1,6-bisphosphatase 2
Homo sapiens ENSG00000165140   fructose-1,6-bisphosphatase 1
Leishmania braziliensis LbrM.04.1170   fructose-1,6-bisphosphatase, cytosolic, putative
Leishmania donovani LdBPK_041170.1   fructose-1,6-bisphosphatase, cytosolic, putative
Leishmania infantum LinJ.04.1170   fructose-1,6-bisphosphatase, cytosolic, putative
Leishmania major LmjF.04.1160  
Leishmania mexicana LmxM.04.1160   fructose-1,6-bisphosphatase, cytosolic, putative
Loa Loa (eye worm) LOAG_08442   fructose-1,6-bisphosphatase
Mus musculus ENSMUSG00000069805   fructose bisphosphatase 1
Mus musculus ENSMUSG00000021456   fructose bisphosphatase 2
Neospora caninum NCLIV_065240   Fructose-1 6-biphosphatase, related
Oryza sativa 4332364   Os03g0267300
Oryza sativa 4325071   Os01g0866400
Saccharomyces cerevisiae YLR377C   fructose 1,6-bisphosphate 1-phosphatase
Schistosoma japonicum Sjp_0215060   ko:K03841 fructose-1,6-bisphosphatase I, putative
Schistosoma mansoni Smp_097370   fructose-16-bisphosphatase-related
Schmidtea mediterranea mk4.009209.00   Fructose-1,6-bisphosphatase
Schmidtea mediterranea mk4.005944.01  
Schmidtea mediterranea mk4.004250.00  
Schmidtea mediterranea mk4.002529.00   Fructose-1,6-bisphosphatase
Trypanosoma brucei gambiense Tbg972.9.4810   fructose-1,6-bisphosphate, cytosolic, putative
Trypanosoma brucei Tb927.9.8720   fructose-1,6-bisphosphatase
Trypanosoma congolense TcIL3000_9_3050   fructose-1,6-bisphosphate, cytosolic, putative
Trypanosoma cruzi TcCLB.506649.70   fructose-1,6-bisphosphatase, cytosolic, putative
Trypanosoma cruzi TcCLB.508351.10   fructose-1,6-bisphosphatase, cytosolic, putative
Toxoplasma gondii TGME49_247510   fructose-bisphospatase II

Essentiality

LmjF.04.1160 has one or more orthologs with essentiality data
Gene/Ortholog Organism Phenotype Source Study
Tb09.211.0540 Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (3 days) alsford
Tb09.211.0540 Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (6 days) alsford
Tb09.211.0540 Trypanosoma brucei no significant loss or gain of fitness in procyclic forms alsford
Tb09.211.0540 Trypanosoma brucei no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms alsford
b4232 Escherichia coli non-essential goodall
TGME49_247510 Toxoplasma gondii Probably essential sidik
Show/Hide essentiality data references
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Druggability index (range: 0 to 1): 0.8

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Rattus norvegicus Fructose-1,6-bisphosphatase Compounds References
Sus scrofa Fructose-1,6-bisphosphatase Compounds References
Mus musculus fructose bisphosphatase 1 Compounds References
Homo sapiens fructose-1,6-bisphosphatase 1 Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model

Ranking Plot

Putative Drugs List

Compound Raw Global Species
0.1588 1 0.5
0.1282 0.3408 0.4787
0.2534 0.2682 1
0.0189 0.5 0.5
0.0189 0.5 0.5
0.1756 0.5 0.5
0.0646 0.5 0.5
0.0378 0.837 0
0.1795 0.793 1
0.2344 1 0.5
0.1251 0.5048 1
0.0338 0.3099 0.5
0.0304 0.5 0.5
0.0189 0.2511 0.3829
0.2598 0.3622 1
0.1691 0.858 1
0.0354 0.392 1
0.4679 1 0.5
0.0484 0.5414 0.5
0.2209 0.4709 0.6415
0.1654 0.424 1
0.0931 0.3282 1
0.0306 0.5 0.5
0.0152 1 1
0.0649 0.6644 1
0.0304 0.338 1
0.0327 1 1
0.2358 0.5692 1
0.0551 1 0.5
0.1267 0.6217 0.5
0.2961 1 1
0.0810067 1 1
0.0656 1 1
0.0164 1 1
0.0316 1 0.5
0.0893 0.5 0.5
0.1037 0.5 0.5
0.0189 0.2594 0.3629
0.2431 1 0.5
0.1865 0.3761 1
0.0488 1 0.5
0.0336 0.8898 0.5
0.0339 0.3777 1
0.1995 0.5355 0.7253
0.0189 0.6063 1
0.3712 0.3369 1
0.0942 0.9681 1
0.2918 1 1
0.1281 0.5 0.5
0.11 0.4962 1
0.0633 1 0.5
0.2871 0.4441 1
0.0153 0.5 0.5
0.317 0.4648 1
0.0358 0.4766 1
0.1691 0.858 1
0.0319 0.5056 0.5
0.065 1 1
0.1782 0.3957 0.6433
0.2598 0.3622 1
0.0378 0.5 0.5
0.0496 0.5212 0.5
1.1921 0.5897 0.8395
0.1467 0.6225 1
0.0378 0.9703 1
0.1944 0.7746 1
0.243 0.605 1
0.0378 0.2514 1
0.0316 0.3561 0.5
0.0621 0.3545 1
0.0939 0.9068 1
0.0649 0.6644 1
0.237 1 1
0.2793 1 0.5
0.1273 1 1
0.451 1 0.5
0.0313 0.7031 0.5
0.1387 0.2592 1
0.3674 0.3344 1
0.2846 0.3689 1
0.1463 1 1
0.0378 0.9404 1
0.071 1 0.5
0.9742 1 1
0.0712 1 0.5
0.0325 0.3146 1
0.0494 1 1
0.0322 1 1
0.0338 1 1
0.2125 0.5348 1
0.0491 0.5613 0.5
0.0485 0.6106 1
0.371 0.3157 1
0.0492 1 0.5
0.0778 1 0.5
0.0822 1 1
0.1944 0.7746 1
0.0467 0.4679 1
0.237 1 1
0.0492 0.6801 0.5
0.0639 0.4573 1
0.0333 0.6135 0.5
0.0306 0.5 0.5
0.0633 1 1
0.4256 1 1
0.1981 0.3433 1
0.0959 1 0.5
0.0639 0.6485 1
0.4115 0.5 0.5
0.1402 0.2928 1
0.1587 0.5 0.5
0.2749 0.4091 1
0.0378 0.5 0.5
0.0189 0.727 1
0.1454 0.4261 1
0.1281 0.5 0.5
0.1981 0.3433 1
0.2373 0.265 1
0.3053 0.5915 1
0.2149 1 1
0.1297 0.5 0.5
0.1654 0.4062 1
0.0613 0.281 1
0.1055 0.7498 1
0.0657 1 0.5
0.1454 0.4261 1
0.0378 0.5 0.5
0.11 0.4962 1
0.2198 1 1
0.4211 0.5 0.5
0.0378 0.5 0.5
0.035 0.3876 0.5
0.0155 0.9652 0.5
0.2278 0.5007 1
0.2728 1 1
0.0189 1 1
0.0378 0.5475 1
0.0965 0.3925 1
0.0378 0.6745 1
0.0167 0.9146 1
0.0318 0.3596 0.861
0.0378 0.3406 1
0.1484 0.4832 1
0.2454 1 0.5
0.1237 1 1
0.0378 0.353 1
0.1248 0.4034 0.5166
0.3274 0.5 0.5
0.1081 0.4056 1
0.1081 0.4056 1
0.2241 1 0.5
0.2694 0.3538 1
0.0338 0.3099 0.5
0.2278 1 1
0.0901 1 0.5
0.0378 0.2514 1
0.1822 0.4313 1
0.2114 1 1
0.0636 1 1
0.0189 0.5 0.5
0.0306 1 1
0.0152 0.378 1
0.2358 0.5692 1
0.0375 0.5175 1
0.3491 1 1
0.3056 1 1
0.0174 0.4075 0.5
0.2475 0.269 1
0.097 1 1
0.111 0.6711 1
0.2846 0.3689 1
0.1282 1 1
0.2598 0.3622 1
0.2534 0.2682 1
0.3454 1 0.5
0.0341 1 1
0.0378 0.7119 1
0.1238 0.3436 1
0.0378 0.5 0.5
0.0307 0.5381 1
0.1238 0.3436 1
0.0189 0.7618 0
0.0635 1 1
0.0308 0.3772 1
0.0482 0.5 0.5
0.2208 1 0.5
0.1682 1 0.5
0.0473 1 1
0.0189 0.6678 1
0.1441 1 0.5
0.062 1 1
0.2114 0.2837 1
0.0306 0.2508 0.5
0.1131 0.2899 1
0.2373 0.265 1
0.1425 0.5404 1
0.1929 0.3535 1
0.0867 1 1
0.1944 0.7746 1
0.1111 1 0.5
0.4904 0.5008 0.8584
0.0312 0.4209 0
0.2178 0.4146 1
0.2589 0.3608 1
0.0334 0.5 0.5
0.2114 0.2837 1
0.0378 0.5 0.5
0.2078 1 0.5
0.0378 0.5367 1
0.2373 0.306 1
0.0966 0.2757 1
0.0378 0.388 1
0.0189 0.6377 1
0.0189 0.3231 0.5
0.2373 0.306 1
0.0366 1 1
0.1072 0.5 0.5
0.2125 0.5348 1
0.1995 0.5355 0.7253
1.135 0.5232 0.8203
0.2869 0.8784 1
0.1782 0.3957 0.6433
0.2373 0.265 1
0.5732 0.5 0.5
0.714 1 1
0.2266 1 1
0.0967 0.5869 1
0.0346 0.8676 0.5
0.0378 0.5 0.5
0.0481 0.2874 1
0.0762 0.3679 1
0.9564 1 0.5
0.1279 0.3678 1
0.221 0.3438 1
0.0378 0.5 0.5
0.1322 0.5862 1
0.0494 0.3309 1
0.0661 1 1
0.0874 0.5 0.5
0.0189 1 1
0.0322 1 1
0.1454 0.4261 1
0.1326 0.3405 1
0.1751 0.482 1
0.5201 0.5 0.5
0.046 0.2631 1
0.2871 0.3751 1
0.033 1 0.5
0.044 0.6243 1
0.9302 0.4909 0.8395
0.0509 0.5177 0.5
0.1114 0.8942 0.5
0.0347 0.7676 1
0.271 0.5 0.5
0.3702 1 0.5
0.2014 1 1
0.0333 0.3302 0.5
0.1146 1 1
0.0313 1 1
0.0947 0.3283 0.6966
0.0469 1 0.5
0.0655 1 1
0.0594 1 0.5
0.2372 0.2642 1
0.215 0.2693 1
0.032 0.3785 1
0.0142 1 0.5
0.0653 0.4681 1
0.0666 0.3494 0.3478
0.147 1 0.5
0.6503 1 1
0.0378 0.6093 1
0.2191 0.5 0.5
0.0655 1 0.5
0.2534 0.2682 1
0.0687 0.5 0.5
0.0469 0.2927 1
0.0967 0.5869 1
0.11 0.2912 1
0.2114 0.2837 1
0.345 0.5 0.5
0.1491 0.3145 1
0.0152 0.6176 1
0.1378 1 0.5
0.0657 1 1
0.4461 0.5 0.5
0.0378 0.2792 1
0.0189 0.5 0.5
0.0189 0.6053 0.5
0.2843 1 0.5
0.3712 0.3369 1
0.2675 1 1
0.2129 1 0.5
0.166417 0.5 0.5
0.0567 0.5721 0.5
0.2476 0.9708 1
0.0171 0.289 0.5
0.0484 0.6592 0.5
0.1095 0.6077 1
0.3561 1 0.5
0.2362 1 1
0.0308 0.3491 1
0.011221 0.5 0.5
0.0567 0.3231 1
0.0378 0.5 0.5
0.0378 0.2787 1
0.031 0.2933 1
0.093 1 1
1.3619 0.5752 0.8203
0.0153 0.9425 1
0.237 1 1
0.00783326 1 1
0.0233 1 0.5
0.1274 0.5607 1
0.0666 0.3494 0.3478
0.0947 0.3055 1
0.0318 1 1
0.0307 0.5381 1
0.1515 0.3358 1
0.2822 0.5 0.5
0.0949 0.3124 1
0.3053 0.5915 1
0.4185 1 1
0.0378 0.4249 1
0.1295 1 0.5
0.0526 0.5 0.5
0.0334 1 0.5
0.0378 0.5 0.5
0.0932 1 1
0.0326 0.5 0.5
0.0658 0.7324 0.5
0.0378 0.5 0.5
0.0726 0.7587 1
0.143 0.4951 1
0.4472 0.4414 1
0.1655 1 0.5
0.0152 0.2694 0.4802
0.0148 0.2948 0.7894
0.2728 1 1
0.2209 0.4709 0.6415
0.3488 0.5 0.5
0.0355 0.4416 1
0.0233338 0.5 0.5
0.0328 0.4844 0.5
0.142 1 1
0.0332 0.4084 1
1.3619 0.5752 0.8203
0.0455 0.4438 1
0.1322 0.5862 1
0.0189 1 0.5
0.0636 1 1
0.0154 1 0.5
0.033 1 0.5
0.2176 0.381 1
0.0473769 1 1
0.0494 0.3309 1
0.1114 0.3312 1
0.882 1 0.5
0.2014 1 1
0.0341 1 0.5
0.0797 1 1
0.1248 0.4034 0.5166
0.8813 1 0.5
0.3674 0.3344 1
0.0189 0.7976 0.5
0.11 0.2912 1
0.0638 1 1
0.1104 0.2619 1
0.1293 0.5 0.5
0.2373 0.265 1
0.1462 0.3131 1
0.2918 1 1
0.0378 0.5 0.5
0.0378 0.5 0.5
0.2793 0.5 0.5
0.4368 1 1
0.0339 0.5 0.5
0.467 0.5 0.5
0.0378 0.8407 1
0.6616 1 1
0.1272 0.3481 1
0.2564 1 0.5
0.2476 0.9708 1
0.1038 1 1
0.237 1 1
0.214 1 0.5
0.1786 0.989 1
0.5372 1 0.5
0.1113 1 1
0.2779 1 1
0.2146 1 0.5
0.7664 1 1
0.0656 1 0.5
0.1944 0.7746 1
0.0666 0.3494 0.3478
0.1104 1 0.5
0.051 0.531 1
0.0326 1 0.5
0.0378 1 0.5
0.0499 0.5191 0.5
0.2553 0.5 0.5
0.0313 0.5 0.5
0.3561 1 0.5
0.0831 0.3738 1
0.1402 0.2928 1
0.4714 0.5 0.5
0.256 0.5308 1
0.097 1 1
0.1127 0.5 0.5
0.2602 1 0.5
0.0536 1 1
0.0302 0.4865 0.5
0.0536 0.2753 1
0.4523 1 1
0.8797 1 0.5
0.0189 0.264 1
0.2564 1 0.5
0.256 0.5308 1
0.3084 1 0.5
0.036 0.5 0.5
0.0466 1 1
0.1282 0.3587 0.4829
0.0587437 0.517346 1
0.1478 0.4183 1
0.0646 1 1
0.0657 1 0.5
0.2945 1 0.5
0.2046 0.2815 1
0.1944 0.7746 1
0.0329 0.3313 1
0.0624 0.2526 0.4511
0.0181 0.3206 1
0.1238 0.3436 1
0.1995 0.5355 0.7253
0.1567 0.2653 1
0.4472 0.4414 1
0.0124066 0.255198 0.689827
0.0335 0.414 1
0.1257 0.485 1
0.7425 1 1
0.1467 0.6225 1
0.2589 0.3608 1
0.1782 0.3957 0.6433
0.0948 0.2628 1
0.0189 0.2594 0.3629
0.0316 0.3502 0.5
0.0488 0.5072 0.5
0.0366 0.263 0.5
0.11 0.2912 1
0.0175 0.2697 0.5
0.2818 1 0.5
0.0139 1 0.5
0.0189 0.5613 1
0.0929 0.5262 1
0.0632 1 1
0.0763 1 1
0.189 1 0.5
0.1767 0.3807 1
0.0455 0.4123 0.5
0.0892 0.7171 1
0.2961 1 1
0.4472 0.4414 1
0.0331 0.3608 1
0.1267 0.3872 1
0.1306 1 1
0.1868 0.5 0.5
0.2278 0.5007 1
0.0378 0.3813 1
0.0378 1 1
0.0378 1 1
0.2114 0.2837 1
0.2037 0.3265 1
0.317 0.4648 1
0.4863 1 0.5
0.215 0.2703 1
0.6735 1 1
0.0497 0.5164 0.5
0.0311 1 0.5
0.0305 0.3292 1
0.0653 0.4681 1
1.3619 0.5752 0.8203
0.1397 0.2597 1
0.0189 0.5 0.5
0.0189 1 1
0.0189 0.6632 0
0.0121695 0.596084 0.705197
0.4472 0.4414 1
0.0955 1 0.5
0.0375 0.5175 1
0.1528 0.3532 0.5579
0.0666 0.3494 0.3478
0.1306 0.4691 1
0.1991 1 1
0.1892 1 1
0.1238 0.3436 1
0.714 1 1
0.1782 0.3957 0.6433
0.1267 0.3872 1
0.2778 1 1
0.2373 0.265 1
0.1655 1 0.5
0.1282 0.3587 0.4829
0.0378 0.4646 1
0.0354 0.392 1
0.0189 0.4978 0
0.1104 0.2619 1
0.0378 0.5 0.5
0.1757 0.2914 1
0.1238 0.3436 1
0.1252 0.376 1
0.0845 1 1
0.0778 0.5136 1
0.4472 0.4414 1
0.0117 0.6832 0.6516
0.7664 1 1
0.2448 1 1
0.1285 1 1
0.9742 1 1
0.1252 0.376 1
0.0472 0.5546 1
0.0189 0.5 0.5
0.2142 0.2673 1
0.0955 0.2557 1
0.1561 0.4542 1
0.0173 1 1
0.2918 1 1
0.3128 1 0.5
0.0189 0.5 0.5
0.0613 0.5937 1
0.1887 0.2706 1
0.0536 0.2753 1
0.0189 0.6321 1
0.1131 0.5 0.5
0.0189 0.3391 1
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0.4759 1 1
0.0378 0.5 0.5
0.0724 0.7701 0.5
0.1615 0.3317 1
0.0810067 1 1
0.1089 0.8773 1
0.0378 1 1
0.0666 0.3494 0.3478
0.0495 1 0.5
0.0848 1 1
0.0154 1 0.5
0.205 1 1
0.0927 0.5048 1
0.0378 0.5 0.5
0.097 1 1
0.0378 0.4488 1
0.108 1 1
0.629 0.5 0.5
0.2374 1 1
0.1455 1 0.5
0.0514 0.5176 0.5
0.0378 0.5 0.5
0.1783 0.5 0.5
0.0303 0.3525 1
0.1618 0.5102 1
0.0378 0.5 0.5
0.1083 1 0.5
0.0638 0.6457 1
0.0378 1 0.5
0.00642046 0.616164 0.614428
0.2527 0.5 0.5
0.0687 1 0.5
0.0189 1 0.5
0.0633 1 1
0.4472 0.4414 1
0.1294 0.7837 1
0.2869 0.8784 1
0.2149 1 1
0.0516 0.5744 0.5
0.2749 0.4091 1
0.3056 1 1
0.2153 1 0.5
0.0152 0.2694 0.4802
0.253 0.5 0.5
0.0341 0.7767 0.5
0.0567 1 0.5
0.1047 1 1
0.2534 0.2682 1
0.2198 0.3309 1
0.0355 0.4416 1
0.0153 0.6625 1
0.4472 0.4414 1
0.1255 0.3837 1
0.2769 1 1
0.4372 1 0.5
0.5184 1 0.5
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0.0494 0.5 0.5
0.2703 1 0.5
0.4396 1 0.5
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0.1612 0.2797 1
0.2724 0.3627 1
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0.0315 0.3763 0.5
0.1905 0.4829 1
0.2144 0.2662 1
0.0189 0.264 1
0.0354 0.392 1
0.0519 1 1
0.236 1 1
0.0963 0.3182 0.7457
0.0502 1 1
0.1612 0.2797 1
0.0189 0.3601 0.5
0.0474 1 1
0.2146 1 0.5
0.0189 0.5 0.5
0.9302 0.4909 0.8395
0.0342 1 0.5
0.1701 1 0.5
0.0378 0.5 0.5
0.1106 1 0.5
0.0519 0.5156 0.5
0.0513 0.3081 0.5
0.1038 1 1
0.0567 0.7433 1
0.0364 0.5 0.5
0.0937 0.9538 0.5
0.0468 0.2707 1
0.4256 1 1
0.1272 0.3481 1
0.2359 1 1
0.137 1 0.5
0.0307 0.5706 1
0.0324 1 0.5
0.0567 0.3231 1
0.0154 0.452 0.5
0.2373 0.306 1
0.1506 0.2963 1
0.0971 0.3469 1
0.0514 1 0.5
0.0841 0.5 0.5
0.0152 0.3024 0.7323
0.1081 0.4056 1
0.1944 0.7746 1
0.0682 0.5 0.5
0.1119 0.2582 1
0.0666 0.3494 0.3478
0.2489 1 0.5
0.0306 0.4295 1
0.031 1 0.5
0.1261 0.2837 1
0.0323 0.2774 0.5
0.0378 0.3772 1
0.1081 0.4056 1
0.0344 0.7591 0.5
0.4471 0.5 0.5
0.0378 0.5443 1
0.0311 1 0.5
0.1131 0.2899 1
0.2606 1 0.5
0.0656 1 0.5
0.0378 0.5 0.5
0.1615 0.3317 1
0.0181 0.4488 0.5
0.0512 0.5758 0.5
0.4853 1 1
0.0173 1 1
0.5054 0.5008 0.8584
0.7666 0.5 0.5
0.0189 0.5503 1
0.4472 0.4414 1
0.2774 0.3888 1
0.0324 0.9666 1
0.0378 0.5 0.5
0.6732 0.5 0.5
0.0501 1 1
0.1081 0.251 1
0.4853 1 1
0.051 0.531 1
0.1462 0.3131 1
0.1252 0.376 1
0.1251 0.5048 1
0.034 0.2985 0
0.1883 0.3476 1
0.0666 0.3494 0.3478
0.0792 0.3573 1
0.1055 0.7498 1
0.5811 1 0.5
0.1269 0.4796 1
0.11 0.4964 1
0.2745 1 0.5
0.0325 0.3229 0.5
0.2513 0.3848 1
0.1823 1 0.5
0.7515 0.5 0.5
0.0491 0.5613 0.5
0.2131 0.2555 1
0.0521 1 0.5
0.0638 0.6457 1
0.1944 0.7746 1
0.0319 1 1
0.1959 1 0.5
0.2014 1 1
0.1941 1 1
0.0378 0.3487 1
0.0125 0.4033 0.5
0.0317 0.6609 1
0.0633 1 1
0.1828 0.3461 0.949
0.171 1 1
0.0326 0.3731 1
0.0331 0.3608 1
0.3181 0.5 0.5
0.2112 0.2717 1
0.0656 1 0.5
0.1612 0.2797 1
0.0348 0.3022 1
0.111 1 0.5
0.0189 0.6584 0.5
0.096 0.5 0.5
0.0378 0.5 0.5
0.1691 0.858 1
0.158 1 1
0.219 0.5 0.5
0.1769 1 1
0.1238 0.3436 1
0.2749 0.4091 1
0.051 0.5549 0.5
0.1528 0.3532 0.5579
0.0921 1 0.5
0.0157 1 0.5
0.1034 1 1
0.0648 0.5 0.5
0.0154 0.2885 1
0.0378 0.3291 1
0.5949 0.5 0.5
0.0971 0.3469 1
0.2334 1 1
0.0189 0.5 0.5
0.3187 0.5 0.5
0.2417 1 0.5
0.0247491 1 1
0.0632 1 1
0.0155 0.31 1
0.018 0.8836 0.5
0.4472 0.4414 1
0.1293 1 0.5
0.0312 0.4916 0.5
0.0189 0.2574 1
0.0154 0.2796 0.5
0.1615 0.3317 1
0.1104 0.2619 1
0.198285 0.5 0.5
0.5681 0.5 0.5
0.1201 1 0.5
0.0332 0.3537 0.5
0.0541 1 1
0.9302 0.4909 0.8395
0.0306 0.2508 0.5
0.2334 1 1
0.0378 0.9703 1
0.0469 0.264 1
0.0153 1 0.5
0.5007 1 1
0.222 0.5673 1
0.2125 0.5 0.5
0.0317 0.5369 0.5
0.1171 0.5 0.5
0.2392 1 0.5
0.1055 1 1
0.0323 0.6581 1
0.1272 0.3481 1
0.0378 0.5 0.5
0.0716 1 1
0.0189 0.6294 1
0.2978 1 0.5
0.0336 0.8913 0.5
0.0455 0.4438 1
0.0378 0.5 0.5
0.0306 0.3929 1
0.1828 0.3461 0.949
0.6342 1 1
0.2373 0.3065 1
0.0687 0.5 0.5
0.0536 0.2753 1
0.2373 0.306 1
0.0323 0.9043 1
0.2534 0.2682 1
0.0488 0.5185 0.5
0.2749 0.4091 1
0.1278 0.3748 1
0.2373 0.265 1
0.0366 1 1
0.2334 1 1
0.1294 0.7837 1
0.4299 1 1
0.0613 0.5937 1
0.0378 0.6156 0.5
0.2114 0.2837 1
0.1295 1 0.5
0.0189 0.3646 0.5
0.2534 0.2682 1
0.0614 0.3626 1
0.0927 0.5048 1
0.0626 0.2568 1
0.3462 0.5 0.5
0.0317 0.5 0.5
0.0189 0.5 0.5
0.0536 0.2753 1
0.0917 1 0.5
0.0189 0.264 1
0.0649 0.6644 1
0.0163 0.6023 1
0.2014 1 1
0.6616 1 1
0.1626 0.8714 1
0.117 0.5 0.5
0.0683 1 0.5
0.1314 1 1
0.0308 0.3772 1
0.2291 0.6642 1
0.0567 0.3231 1
0.3187 0.8143 1
0.1078 0.2733 1
0.2373 0.3061 1
0.6503 1 1
0.3712 0.3369 1
0.1051 1 1
0.0189 1 0.5
0.1282 0.3587 0.4829
0.2037 0.3252 1
0.0513 0.3373 1
0.0671 0.6817 1
0.1981 1 0.5
0.0319 0.2776 0.5
0.0378 0.5 0.5
0.7994 0.5 0.5
0.2576 0.3531 1
0.0515 1 1
0.1278 0.3748 1
0.2947 0.3644 1
0.0664 1 1
0.1784 0.5694 1
0.0333 0.4203 0.5
0.0305 0.3529 0.5
0.1113 1 1
0.0649 0.6644 1
0.0375 0.5175 1
0.0302 0.4634 1
0.1402 0.2928 1
0.1095 0.6663 1
0.1463 1 1
0.0154 0.8473 1
0.0791 1 0.5
0.1425 1 0.5
0.0153 0.9425 1
0.0335 0.414 1
0.4185 1 1
0.0378 0.3356 0.8907
0.0189 1 0.5
0.0873 0.5 0.5
0.7508 0.5 0.5
0.1055 0.7498 1
0.0629 0.5 0.5
0.2514 0.3235 1
0.2278 0.5007 1
0.2278 0.5007 1
0.7425 1 1
0.2358 0.5692 1
0.3617 1 0.5
0.317 0.4648 1
0.0842 1 1
0.143 0.4951 1
0.0513 1 0.5
0.1272 0.3481 1
0.0332 1 0.5
0.0378 0.2776 1
0.1081 0.4056 1
0.0653 0.4681 1
0.2125 0.5348 1
0.0172 0.5 0.5
0.1286 0.2567 1
0.1038 1 1
0.1837 1 0.5
0.2778 1 1
0.0517 0.2873 1
0.0491 0.5613 0.5
0.371 0.3157 1
0.0356 0.5 0.5
0.0547 0.7868 1
0.0326 0.5 0.5
0.0366 1 1
0.1782 0.3957 0.6433
0.0325 0.2773 0.5
0.0358 0.4766 1
0.2696 0.3268 1
0.1612 0.2797 1
0.0326 1 0.5
0.0959 1 0.5
0.0181 1 0.5
0.0326 0.3731 1
0.1615 0.3317 1
0.0341 1 0.5
0.2475 0.269 1
0.2176 0.3283 1
0.0189 0.3392 1
0.0962 1 1
0.0189 0.5 0.5
0.28 1 0.5
0.033 0.5 0.5
0.0308 0.3772 1
0.1051 1 1
0.0354 0.392 1
0.2914 0.5 0.5
0.1569 0.2837 1
0.4472 0.4414 1
0.2334 1 1
0.0189 0.3622 1
0.4472 0.4414 1
0.2359 1 1
0.2945 1 0.5
0.0624 0.2526 0.4511
0.3972 0.459 1
0.0378 0.4303 0.5
0.0378 0.5 0.5
0.5221 0.5 0.5
0.2373 0.265 1
0.1043 1 1
0.0309 0.9266 1
0.0378 0.5 0.5
0.4368 1 1
0.2395 0.433 1
0.0619 1 1
0.0567 0.3231 1
0.0469 0.264 1
0.0567 0.3231 1
0.1561 0.4542 1
0.0792 0.2978 1
0.0438 0.9703 1
0.3187 0.8143 1
0.1072 0.2693 1
0.0189 0.5 0.5
0.2373 0.306 1
0.1238 0.2869 1
0.4185 1 1
0.0341 0.3214 0.5
0.1642 0.3247 1
0.1272 0.3481 1
0.1369 0.6375 1
0.0663 0.5 0.5
0.2359 1 1
0.2739 0.5 0.5
0.1237 1 1
0.1135 0.3469 1
0.0311 0.5 0.5
0.2489 1 0.5
0.3575 0.354 1
0.0666 1 1
0.0331 0.3231 0.5
0.0339 0.3777 1
0.0378 0.6093 1
0.093 0.3093 1

Assayability

Assay information

  • Assay for D-Fructose-1,6-Diphosphatase (3.1.3.11 ) Sigma-Aldrich
  • Automatic link to known assays based on EC numbers.

Reagent availability

No reagent availability information for this target.

Bibliographic References

2 literature references were collected for this gene.

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Gene identifier LmjF.04.1160 (Leishmania major),
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