Detailed view for Bm1_06570

Basic information

TDR Targets ID: 239909
Brugia malayi, 3-oxo-5-alpha-steroid 4-dehydrogenase 1
Source Database / ID:  GenBank

pI: 8.7862 | Length (AA): 131 | MW (Da): 15159 | Paralog Number: 0

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 1

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF02544   3-oxo-5-alpha-steroid 4-dehydrogenase

Gene Ontology

Mouse over links to read term descriptions.
GO:0016627   oxidoreductase activity, acting on the CH-CH group of donors  
GO:0016021   integral to membrane  
GO:0005737   cytoplasm  
GO:0006629   lipid metabolic process  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

No model available for this protein in Modbase.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_128852)

Species Accession Gene Product
Arabidopsis thaliana AT2G38050   probable steroid reductase DET2
Brugia malayi Bm1_06570   3-oxo-5-alpha-steroid 4-dehydrogenase 1
Caenorhabditis elegans CELE_F42F12.3   Protein F42F12.3
Caenorhabditis elegans CELE_F19H6.4   Protein F19H6.4
Entamoeba histolytica EHI_197070   steroid 5-alpha reductase, putative
Homo sapiens ENSG00000145545   steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
Homo sapiens 6716   steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
Leishmania braziliensis LbrM.17.1210   3-oxo-5-alpha-steroid 4-dehydrogenase-like protein
Leishmania donovani LdBPK_171200.1   3-oxo-5-alpha-steroid 4-dehydrogenase-like protein
Leishmania infantum LinJ.17.1200   3-oxo-5-alpha-steroid 4-dehydrogenase-like protein
Leishmania major LmjF.17.1100   3-oxo-5-alpha-steroid 4-dehydrogenase-like protein
Leishmania mexicana LmxM.17.1100   3-oxo-5-alpha-steroid 4-dehydrogenase-like protein
Loa Loa (eye worm) LOAG_07203   hypothetical protein
Mus musculus ENSMUSG00000021594   steroid 5 alpha-reductase 1
Mus musculus ENSMUSG00000038541   steroid 5 alpha-reductase 2
Mycobacterium ulcerans MUL_3208   hypothetical protein
Oryza sativa 9272051   Os11g0184100
Oryza sativa 4324809   Os01g0851600
Schmidtea mediterranea mk4.000630.02   3-oxo-5-alpha-steroid 4-dehydrogenase 1
Schmidtea mediterranea mk4.000630.01  
Trypanosoma brucei gambiense Tbg972.8.1930   3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative
Trypanosoma brucei Tb927.8.2480   3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative
Trypanosoma cruzi TcCLB.509331.70   3-oxo-5-alpha-steroid 4-dehydrogenase, putative
Trypanosoma cruzi TcCLB.504427.70   3-oxo-5-alpha-steroid 4-dehydrogenase, putative
Toxoplasma gondii TGME49_304480   3-oxo-5-alpha-steroid 4-dehydrogenase
Trichomonas vaginalis TVAG_146690   3-oxo-5-alpha-steroid 4-dehydrogenase, putative
Trichomonas vaginalis TVAG_391520   3-oxo-5-alpha-steroid 4-dehydrogenase, putative
Trichomonas vaginalis TVAG_096490   3-oxo-5-alpha-steroid 4-dehydrogenase, putative

Essentiality

Bm1_06570 has one or more orthologs with essentiality data
Gene/Ortholog Organism Phenotype Source Study
Tb927.8.2480 Trypanosoma brucei no significant loss or gain of fitness in bloodstream forms (3 days) alsford
Tb927.8.2480 Trypanosoma brucei significant gain of fitness in bloodstream forms (6 days) alsford
Tb927.8.2480 Trypanosoma brucei no significant loss or gain of fitness in procyclic forms alsford
Tb927.8.2480 Trypanosoma brucei no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms alsford
CELE_F19H6.4 Caenorhabditis elegans embryonic lethal wormbase
TGME49_304480 Toxoplasma gondii Probably non-essential sidik
Show/Hide essentiality data references
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Rattus norvegicus Steroid 5-alpha-reductase 2 Compounds References
Rattus norvegicus Steroid 5-alpha-reductase 1 Compounds References
Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) Compounds References
Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) Compounds References
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets
Obtained from network model

Ranking Plot

Putative Drugs List

Compound Raw Global Species
0.1224 0.6488 1
0.1205 0.3498 1
0.0151 0.5 0.5
0.0048 0.7671 0.7671
0.0831 0.2804 0.6634
0.097 0.3611 0.7295
0.0322 0.6092 1
0.0897 0.2506 0.6005
0.147 0.6675 1
0.9763 0.8569 0.8569
1.4967 0.2805 0.6332
4.489 0.3714 1
0.0312 0.3936 1
3.1097 0.5677 0.5752
0.0641 0.3152 0.6762
0.0492 0.3469 0.4394
0.0615 0.3771 0.5693
0.128 0.4016 0.7184
0.0827 0.3107 0.5327
0.0365 0.3588 1
0.0737 0.3643 0.3941
0.0193 0.5623 0.5852
0.0929 0.4535 0.8136
0.0306 0.3568 0.6237
0.100512 0.5 0.5
0.2514 0.6871 0.8567
0.0365 0.4195 0.6543
0.0244 0.2805 1
0.0755 0.3002 0.5021
0.0222467 0.292253 0.292253
0.0685 0.8545 1
0.0051 0.8747 0.8747
0.0189 0.6125 0.8167
4.489 0.3714 1
0.055 0.4862 0.4851
4.489 0.3714 1
0.0304 0.3508 1
0.0356 0.4326 0.4326
0.0303 0.3094 0.4879
0.014967 0.602105 0.688562
0.014967 0.602105 0.688562
0.0303 0.8021 1
0.0814 0.3917 0.7892
0.0821 0.474 1
0.0309 0.3491 0.3491
0.0323 0.3882 1
0.0634 0.5483 0.5482
0.0826 0.3134 0.5609
0.097 0.3611 0.7295
0.0322 0.6092 1
0.0499 0.2845 0.5217
0.0976 0.264 0.7118
0.0162536 0.603839 0.690114
0.0221109 0.292253 0.292253
0.0503 0.6429 1
0.0492 0.5818 0.9031
0.0608 0.4289 1
0.1825 0.532 1
4.489 0.3714 1
0.156 0.4328 0.4325
4.489 0.3714 1
0.0977 0.3848 0.7866
2.4884 0.3644 1
0.0939 0.2914 0.7598
0.0956 0.4597 0.5238
0.0155 0.8338 0.8338
0.0341 0.7943 1
4.489 0.3714 1
0.0309 0.3491 0.3491
0.1461 0.8295 1
0.0317 0.879 1
4.489 0.3714 1
2.9289 0.7476 1
0.2554 0.5867 0.6588
0.0337 0.3361 1
0.0736 0.3876 0.3875
0.1538 0.4643 1
0.0919 0.2729 1
2.8815 0.5485 1
0.0948 0.2759 0.9856
2.9289 0.7476 1
0.0156 0.2642 0.5763
0.1019 0.2937 0.6939
0.0563 0.4577 1
0.0931 0.3761 0.3845
0.043 0.301 0.5336
0.093 0.9469 1
0.0044 1 1
0.0336 0.2682 0.4509
0.1081 0.6029 1
4.489 0.3714 1
0.0199 0.865 0.86
0.0347 0.4117 1
0.0581 0.4501 1
0.0228 0.2809 0.2808
4.5018 0.9192 1
1.0494 0.9945 0.9945
0.0345 0.6525 1
0.0322 0.3421 1
0.0817 0.4945 1
0.1825 0.532 1
0.0302 0.2762 0.4626
0.0566 0.5931 1
2.9289 0.7476 1
4.489 0.3714 1
0.0047 1 1
2.756 0.3218 1
0.0309 0.7894 1
4.489 0.3714 1
0.0976 0.264 0.7118
0.097 0.3372 0.7969
0.0301 0.5 0.5
0.0321 0.2608 0.6448
1.8896 0.9075 0.9075
0.0377 0.9858 1
0.2554 0.5867 0.6588
0.9613 0.3432 1
0.0116 0.4497 1
2.6848 0.8245 1
0.0889 0.3351 1
0.0134 0.2794 0.4368
0.0377 0.7787 0.8954
2.30285 0.802309 0.802305
4.489 0.3714 1
0.0996 0.3162 1
0.0959 0.271 0.7949
4.489 0.3714 1
0.1783 0.692 1
0.1326 0.4292 0
3.1097 0.5677 0.5752
0.0641 0.8144 1
0.0781 0.9869 1
0.0197 0.251 0.8213
0.0203 0.5803 0.5803
4.489 0.3714 1
0.0189 0.2527 0.8419
4.489 0.3714 1
1.5569 0.3919 0.3919
0.0574 0.485 0.485
0.0307 0.3627 1
3.1097 0.5677 0.5752
0.049 0.2971 0.2971
0.0442 0.6402 0.6402
0.0151 0.267 1
4.489 0.3714 1
2.1769 0.9098 1
2.6086 0.481 0.5798
0.0159 0.6109 0.6088
2.9289 0.7476 1
2.4884 0.3644 1
4.489 0.3714 1
0.0298 0.2733 0.4479
2.4884 0.3644 1
0.3273 0.4511 0.5136
0.0973 0.2994 0.7286
0.0318 0.5727 1
0.0044 0.5714 1
0.0684 0.612 0.612
0.1647 0.5662 0.5988
2.9289 0.7476 1
0.23 0.2683 1
0.0199 0.2875 0.2955
0.0313 0.3319 0.4248
4.489 0.3714 1
0.1844 0.3744 1
0.0193 0.5113 0.7633
0.1205 0.3498 1
0.0948 0.2542 0.752
0.0221 0.3061 0.5431
0.1783 0.692 1
0.0817 0.4945 1
2.2276 0.4579 0.5918
0.0329 0.392 0.6783
1.6262 0.456 0.75
0.022 1 1
0.158 0.9588 0.9588
0.4766 0.5003 0.5003
0.049 0.288 0.7696
0.0826 0.3122 0.6881
0.9763 0.8569 0.8569
0.0716 0.8479 1
0.009 0.3115 0.304
4.489 0.3714 1
0.0377 0.4229 1
0.0617 0.8643 1
0.2735 0.9744 0.9702
0.1243 0.2811 0.6334
4.489 0.3714 1
0.329 0.4053 0.4053
4.5181 0.6155 1
0.1459 0.8726 1
0.257 0.9203 1
2.9289 0.7476 1
0.0965 0.3246 0.7368
0.0522 0.8525 0.8524
0.0203 0.5913 0.6169
0.0189 0.2654 0.9535
0.0823 0.3831 0.7741
0.0976 0.264 0.7118
2.6192 0.6446 1
2.4884 0.3644 1
0.1844 0.3744 1
0.0151 0.372 0.4739
0.3273 0.4511 0.5136
1.6278 0.262 1
0.0657 0.2524 0.6337
0.0789 0.4355 0.4355
0.0051 1 1
0.0502 0.386 1
0.5694 0.3317 0.55
4.489 0.3714 1
0.0242 0.278 1
0.0842 0.7584 0.7735
0.0717 0.3558 0.3547
0.0897 0.2515 0.5947
0.0315 0.3831 0.9907
0.0377 0.4924 0.6548
0.0199 0.5232 0.5232
0.1156 0.3178 0.871
0.0223 0.8693 0.8693
2.756 0.3218 1
0.0501 0.2676 0.9562
0.1411 0.8531 1
3.278 0.6238 1
0.0869 0.3798 1
0.257 0.9203 1
0.1426 0.4705 1
0.1673 0.9747 1
0.0152 0.2981 1
0.165 0.6386 1
0.0348 0.2684 1
0.0931 0.3761 0.3845
0.0189 0.6051 0.6041
0.0433 0.612 1
0.1343 0.2919 0.8247
0.1885 0.5137 1
0.0837 0.3241 0.7407
0.1426 0.3946 1
0.0776 0.4367 0.6681
0.0524 0.5237 1
0.0894 0.2712 0.7223
0.0377 0.4013 1
0.0892 0.352 1
4.489 0.3714 1
0.0889 0.263 0.8642
0.1716 0.2611 0.5152
0.0437 0.28 0.3684
0.0929 0.5879 1
4.489 0.3714 1
0.1538 0.4643 1
0.0215231 0.5 0.5
2.15268 0.698025 0.698023
0.0303 0.5421 0.8039
2.9289 0.7476 1
0.0982 0.275 1
0.0176 0.2748 1
0.0155 0.4365 0.6336
0.0433 0.612 1
0.0494 0.4044 0.4044
0.0375 0.426 0.4408
0.0205 0.8755 0.8729
2.9289 0.7476 1
2.9289 0.7476 1
0.0365 0.2517 0
0.1433 0.278 1
0.0511 0.5521 0.8077
0.0206 0.4742 0.4742
0.0964 0.2946 0.777
2.9289 0.7476 1
2.4884 0.3644 1
0.1504 0.5737 1
0.0755 0.7879 1
0.748 0.8609 1
0.0155 1 1
0.0574 0.8506 0.8506
0.0314 0.3831 1
0.0377 0.4924 0.6548
0.0308 0.8498 1
0.8989 0.6351 1
0.0313 0.3872 1
0.0051 1 1
0.0304 0.3036 0.3036
0.0156 0.3728 1
0.0494 0.4044 0.4044
0.0726 0.4232 1
1.1633 0.2926 0.2926
4.489 0.3714 1
0.0307 0.6775 1
3.0912 0.4564 1
3.1097 0.5677 0.5752
0.0502 0.2999 0.6054
0.0101 1 1
2.4884 0.3644 1
0.1647 0.5662 0.5988
0.0507 0.2909 0.8026
0.0499 0.3381 0.377
0.0446 0.4554 1
4.489 0.3714 1
0.0625 0.4162 1
0.005 0.257 0.257
0.0319 0.4198 0.4134
0.0986 0.3046 0.8048
0.0616 0.7591 1
0.0377 0.2514 0.2514
0.0313 0.2888 0.7387
0.0309 0.3491 0.3491
1.5298 0.3534 1
0.3273 0.4511 0.5136
4.489 0.3714 1
0.137 0.5898 1
4.489 0.3714 1
0.0223 0.8693 0.8693
0.0505 0.3178 0.3917
0.0316 0.3728 0.9929
0.0715 0.4141 0.6481
0.0309 0.331 0.4063
0.9066 0.3235 1
4.489 0.3714 1
0.0344 0.2635 0.8313
0.0829 0.5811 1
0.137 0.6459 1
0.1504 0.263 0.3089
0.2576 0.3056 0.6411
0.0214 0.4089 0.4071
0.0315 0.2703 0.2703
0.0471 0.5528 1
4.489 0.3714 1
0.0189 0.2654 0.9535
0.0043 1 1
0.0473 0.4032 0.6395
0.6639 0.7437 0.9084
0.0935 0.9911 1
0.0931 0.3761 0.3845
4.0689 0.5834 1
0.028 0.4047 0.3784
0.0194 0.6655 0.6655
3.1097 0.5677 0.5752
0.0317 0.372 0.6615
1.6356 0.4141 1
0.0631 0.3275 0.3268
0.0389 0.4987 1
4.489 0.3714 1
4.489 0.3714 1
1.386 0.5888 1
0.0117 0.3547 0.3547
0.0302 0.3553 1
4.489 0.3714 1
0.1408 0.2812 0.8905
0.2554 0.5867 0.6588
0.0948 0.2612 0.7031
0.2554 0.5867 0.6588
3.266 0.7475 1
2.756 0.3218 1
0.0158 0.3511 0.4677
0.0503 0.5803 0.9022
0.329 0.4053 0.4053
0.0155 0.3358 0.9445
0.0729 0.9595 1
4.489 0.3714 1
0.0563 0.7029 1
0.1205 0.3498 1
0.0312 0.3155 0.6385
0.099 0.2719 0.7462
1.8945 0.4286 1
0.0307 0.6508 0.6472
1.7874 0.3467 1
0.0242 0.7105 0.7858
0.0612 0.6382 1
0.3708 0.4616 0.964
0.0771 0.4257 1
0.0637 0.3834 1
0.0672 0.6859 0.6859
0.0776 0.6341 0.6303
0.0897 0.4197 0.8469
0.1134 0.5002 1
3.1097 0.5677 0.5752
0.0331 0.8295 1
4.489 0.3714 1
0.0377 0.8762 0.8762
0.1336 0.3402 1
4.489 0.3714 1
0.4461 0.3411 0.5362
0.9763 0.8569 0.8569
4.489 0.3714 1
0.0508 0.5987 0.9331
0.0638 0.5069 1
0.6263 0.5972 1
0.1205 0.3498 1
0.0189 0.3094 0.3094
0.0342 0.9159 1
0.0377 0.4773 0.4773
0.0192 0.2683 1
0.0213 0.3061 0.3998
2.1702 0.8756 1
0.0464 0.5045 1
4.489 0.3714 1
0.0659 0.409 1
0.0377 0.4329 0.4329
0.0953 0.2998 0.3488
0.257 0.9203 1
0.07 0.9489 1
0.0377 0.3591 0.9987
0.0093 0.5 0.5
4.489 0.3714 1
0.0194 0.5584 0.785
0.0972 0.68 0.6796
0.0053 1 1
0.0377 0.6708 1
2.1965 0.4016 1
4.489 0.3714 1
0.0763 0.6607 0.6669
0.2596 0.8826 1
0.4939 0.6409 1
0.0973 0.2746 0.5649
0.0304 0.3599 0.9205
0.0982 0.275 1
0.1441 0.4276 1
0.0878 0.2725 0.6057
3.1097 0.5677 0.5752
0.0507 0.2909 0.8026
4.489 0.3714 1
4.489 0.3714 1
0.0077 0.3008 0.3961
2.4884 0.3644 1
0.0193 0.5001 0.5001
0.0303 0.5421 0.8039
1.2663 0.5209 1
0.0238614 0.448189 0.659188
0.0627 0.7684 1
0.0854 0.3683 0.7206
0.0099 1 1
2.2276 0.4579 0.5918
0.0717 0.3558 0.3547
2.1702 0.8756 1
2.9289 0.7476 1
2.756 0.3218 1
0.5091 0.3109 0.7032
0.1031 0.709 1
0.0823 0.3092 0.3091
0.016 0.3705 0.3705
4.489 0.3714 1
0.1504 0.263 0.3089
0.2651 0.8116 1
0.0972 0.68 0.6796
4.489 0.3714 1
0.0314 0.7096 0.7086
0.0827 0.3107 0.5327
0.2069 0.3611 1
0.0377 0.4229 1
0.0156 0.439 1
0.0597 0.7472 1
0.1643 0.4518 1
4.489 0.3714 1
0.0318 0.3802 0.4248
0.0803 0.4082 1
0.097 0.3246 0.7198
0.0669 0.3891 0.5308
0.0995 0.2723 0.7471
0.0318 0.3358 0.7304
0.0154 0.501 0.6181
0.0946 0.2644 0.7124
0.0204 0.5561 1
0.0513 0.3003 0.4893
0.0563 0.5123 0.5123
1.7503 0.3499 0.8344
4.489 0.3714 1
0.1887 0.5154 0.5154
0.9763 0.8569 0.8569
0.0193 0.3551 1
0.0993 0.2716 0.7452
0.0708 0.5103 0.9792
0.0931 0.2689 0.8923
0.0613 0.2615 0.2615
0.0826 0.2821 0.6607
0.0631 0.3275 0.3268
2.9289 0.7476 1
3.0818 0.5819 1
0.1156 0.3092 0.8316
0.0402 0.2972 0.842
0.2406 0.3775 0.4598
3.266 0.7475 1
0.0195 0.6818 0.6818
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0.2576 0.3056 0.6411
4.489 0.3714 1
0.0303 0.3379 0.3379
0.0878 0.2725 0.6057
0.0161 0.3477 0.3477
0.0162 0.3004 0.3269
0.1538 0.4643 1
4.489 0.3714 1
0.2484 0.4982 0.6445
0.2576 0.3056 0.6411
1.2717 0.4512 1
4.489 0.3714 1
0.0317 0.5999 0.5998
0.0511 0.7206 1
0.0304 0.3036 0.3036
0.0215 0.4675 0.4662
4.489 0.3714 1
0.0826 0.3134 0.5609
2.8807 0.2721 1
4.3073 0.4416 1
2.6086 0.481 0.5798
0.0694 0.5808 0.5808
0.137 0.5898 1
2.2373 0.6805 1
0.0044 1 1
3.1097 0.5677 0.5752
0.1306 0.411 0.411
0.0309 0.5 0.5
0.032 0.3782 1
0.0154 0.7728 0.7728
0.257 0.9203 1
0.0332 0.3446 1
0.0935 0.5305 1
0.0511 0.5521 0.8077
2.5946 0.4038 0.8933
0.257 0.9203 1
0.8989 0.6351 1
0.174 0.7356 1
0.0304 0.3036 0.3036
0.0344 0.4035 1
0.0308 0.7534 1
0.0755 0.3002 0.5021
0.0965 0.2637 0.7274
0.0489 0.4293 0.4293
0.0316 0.8159 1
0.1538 0.4643 1
0.0349 0.74 0.995
0.0241 0.5281 1
0.0878 0.2731 0.7253
0.1883 0.3707 1
0.0161 0.3776 1
0.0355 0.6224 1
3.266 0.7475 1
1.203 1 1
0.2554 0.5867 0.6588
4.489 0.3714 1
0.0207 1 1
0.0377 0.4773 0.4773
0.049 0.2971 0.2971
0.0622 0.6628 0.6627
0.0137 0.2726 0.9213
0.0734 0.3288 0.4298
0.0544 0.4724 1
0.296 0.3283 1
0.0224319 0.265403 0.57257
0.329 0.4053 0.4053
0.0345 0.4802 0.974
0.0302 0.3359 0.8901
0.257 0.9203 1
0.0190038 1 1
0.0307 0.3732 1
0.0345 0.4802 0.974
2.9289 0.7476 1
0.2406 0.3775 0.4598
0.0362 0.4217 1
0.0973 0.2994 0.7286
0.0748 0.3718 0.6309
0.158 0.9588 0.9588
0.0344 0.3819 0.9977
3.1097 0.5677 0.5752
0.0051 1 1
0.0331 0.4525 0.7016
0.2145 0.6847 0.6846
0.0499 0.3415 0.6429
4.4851 0.8173 1
0.0045 1 1
4.489 0.3714 1
0.0153 1 1
0.0755 0.7879 1
2.1705 0.5125 1
0.3273 0.4511 0.5136
4.489 0.3714 1
0.158 0.4828 0.4828
4.489 0.3714 1
0.0426 0.3898 1
0.0329 0.3912 1
0.0156 0.3876 1
0.0043 0.3597 0.3597
0.0972 0.68 0.6796
0.0309 0.3491 0.3491
0.0639 0.3773 0.8789
1.723 0.6663 1
0.6033 0.4048 0.9631
0.0314 0.8556 0.8556
2.4884 0.3644 1
2.7217 0.3452 0.9404
0.0319 0.4198 0.4134
0.0402 0.2972 0.842
0.0995 0.28 0.8137
0.0196 0.6019 1
0.0613 0.2615 0.2615
0.0988 0.2718 0.794
0.0971 0.2848 0.7611
0.4879 0.3177 0.6993
0.0893 0.2575 0.9145
3.7359 0.3149 1
0.0348 0.2684 1
1.7503 0.3499 0.8344
0.0339 0.2803 0.5115
0.0375 0.426 0.4408
0.0204 0.8761 0.8736
0.0303 0.5421 0.8039
0.0153 0.4879 1
0.0511 0.5521 0.8077
0.0238 0.3279 0.3369
0.039 0.4649 1
0.0333 0.8717 1
4.489 0.3714 1
0.257 0.9203 1
0.2966 0.2619 1
0.0748 0.3718 0.6309
0.0524 0.5966 1
0.0216 0.3756 0.4728
0.0781 0.4379 0.59
0.0386 0.5441 1
0.158 0.9588 0.9588
0.1408 0.2812 0.8905
0.0629 0.4138 1
2.4884 0.3644 1
2.9289 0.7476 1
0.005 0.5344 0.4946
0.0948 0.2542 0.752
0.0325 0.403 0.9872
0.0302 0.291 0.573
0.2554 0.5867 0.6588
0.0318 0.3223 1
0.0313 0.6785 0.6772
0.0205 0.5881 0.5881
0.064 0.7488 1
0.0263455 0.5 0.5
0.329 0.4053 0.4053
0.0333 0.8717 1
0.2406 0.3775 0.4598
0.0053 0.5 0.5
2.65399 0.594144 1
0.3273 0.4511 0.5136
0.0928 0.705 1
2.9289 0.7476 1
3.1097 0.5677 0.5752
0.0193 0.5257 0.5257
0.0897 0.2506 0.6005
0.0202 0.4653 1
0.1783 0.692 1
0.0377 0.4924 0.6548
0.0484 0.2836 0.4117
4.5181 0.6155 1
0.1055 0.3467 0.3799
3.7829 0.9132 1
4.489 0.3714 1
0.0322 0.6265 1
0.0195 0.2728 0.2728
0.0194 0.5523 0.5523
0.2435 0.4625 1
0.0272117 0.919713 1
4.489 0.3714 1
0.0195 0.2603 0.2603
4.489 0.3714 1
0.0976 0.264 0.7118
0.0973 0.2994 0.7286
3.266 0.7475 1
0.0897 0.2515 0.5947
1.2481 0.9374 1
0.1096 0.7751 1
4.489 0.3714 1
0.0972 0.68 0.6796
0.0044 0.2692 0.2692
0.0253 0.3363 0.3819
0.0377 0.4035 0
0.0897 0.2506 0.6005
0.0362 0.4217 1
4.489 0.3714 1
0.0242 0.278 1
0.0977 0.2752 0.8034
0.0366 0.4717 0.8103
0.0304 0.3036 0.3036
0.0204 0.8774 0.8774
1.677 0.6142 1
0.0973 0.2746 0.5649
2.4884 0.3644 1
2.4884 0.3644 1
0.0377 0.7809 0.7809
0.091 0.9591 1
0.0643 0.9943 1
0.0097 1 1
0.1793 0.3077 1
0.3144 0.2578 1
3.5259 0.7705 0.9816
0.1087 0.284 1
0.0043 1 1
2.4884 0.3644 1
1.17328 1 1
0.0313 0.3783 1
0.5814 0.3943 0.9985
0.0377 0.4694 1
0.064 0.255 1
0.0042 0.3015 0.3634
4.489 0.3714 1
0.0316 0.8159 1
0.0503 0.3134 0.659
0.0637 0.6597 1
0.0651 0.8102 1
0.0726 0.6373 0.6372
0.0134 0.2794 0.4368
0.0203 0.4202 0.5653
0.2514 0.6871 0.8567
3.1097 0.5677 0.5752
0.0444 1 1
0.0325 0.4338 1
0.0307 0.4529 1
0.0302 0.3633 0.8609
2.6086 0.481 0.5798
2.9289 0.7476 1
2.9289 0.7476 1
0.0322 0.9009 0.9009
0.0189 0.6822 0.7208
0.043 0.3533 0.9253
0.0692 0.5949 0.5949
4.489 0.3714 1
0.1461 0.8295 1
0.0426 0.4364 1
0.0307 0.4522 1
0.0309 0.3026 0.6156
0.1647 0.5662 0.5988
4.489 0.3714 1
0.0377 0.882 0.882
0.0242 0.2701 1
0.2025 0.3667 0.3667
0.0313 0.8421 1
0.0189 0.9366 1
4.489 0.3714 1
4.489 0.3714 1
0.143 0.3823 1
0.0324 0.3184 0.3184
0.1802 0.2613 0.5154
0.0801 0.3148 0.4321
0.0493 0.2861 0.9321
0.0426 0.4364 1
0.0375 0.4326 0.4326
0.0897 0.2515 0.5947
0.0044 0.5 0.5
0.0776 0.4367 0.6681
0.0326 0.4039 1
0.009 0.297 0.297
3.0351 0.3943 1
0.0109674 1 1
0.0643 0.9943 1
0.0201 1 1
0.0882 0.3007 1
0.8989 0.6351 1
0.12751 0.791993 0.791993
2.3758 0.3846 1
0.099 0.3357 1
1.6062 0.3145 1
0.1022 0.2915 0.7226
0.0505 0.9202 1
4.489 0.3714 1
0.0595 0.6035 0.7801
0.0738 0.3059 1
0.1326 0.4292 0
0.096 0.2936 0.785
0.0307 0.676 0.676
4.489 0.3714 1
0.0157 0.3981 0.3904
2.1705 0.5125 1
0.0508 0.5005 1
0.021 0.3888 0.3752
0.2145 0.6847 0.6846
0.0973 0.2635 0.7099
0.0252 0.6255 1
0.0508 0.9204 1
2.1705 0.5125 1
0.0887 0.6179 1
4.489 0.3714 1
0.0335 0.9713 1
3.1097 0.5677 0.5752
0.0826 0.3134 0.5609
0.0552 0.313 0.4834
0.2411 0.36 0.36
4.489 0.3714 1
0.0195 0.275 0.275
0.1097 0.3204 1
1.83 0.6797 1
0.0221859 0.5 0.5
0.0973 0.2641 0.7108
0.0242 0.7105 0.7858
2.9289 0.7476 1
0.0198 0.253 0.2517
0.0153 0.2809 0.5073
0.07 0.9489 1
0.0867 0.3029 0.8296
0.0314 0.4181 0.4348
0.8226 0.2823 1
0.0953 0.2992 0.3475
0.0313 0.3862 0.626

Assayability

Assay information

No assay information for this target.

Reagent availability

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Gene identifier Bm1_06570 (Brugia malayi), 3-oxo-5-alpha-steroid 4-dehydrogenase 1
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