Detailed view for Bm1_39765

Basic information

TDR Targets ID: 243467
Brugia malayi, Protein kinase domain containing protein
Source Database / ID:  GenBank

pI: 9.1603 | Length (AA): 673 | MW (Da): 76777 | Paralog Number: 0

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00069   Protein kinase domain
PF02149   Kinase associated domain 1

Gene Ontology

Mouse over links to read term descriptions.
GO:0004674   protein serine/threonine kinase activity  
GO:0004672   protein kinase activity  
GO:0005524   ATP binding  
GO:0004713   protein tyrosine kinase activity  
GO:0006468   protein amino acid phosphorylation  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

There are 8 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
2 315 1j1b (A) 40 370 29.00 0 1 0.590668 0.3
2 285 3kvw (A) 121 462 31.00 0.00000000014 0.97 0.462491 0.64
4 279 4fl3 (A) 340 622 23.00 0 1 0.677204 -0.23
5 275 5k5x (A) 566 942 27.00 0 1 0.630775 -0.04
18 429 4ysj (A) 14 432 26.00 0 1 0.725284 0.1
25 354 4d2w (A) 4 332 54.00 0 1 1.13844 -0.84
30 366 5iso (A) 14 372 44.00 0 1 1.01084 -0.06
570 673 3ose (A) 696 795 24.00 0 1 0.484632 -0.86

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_133787)

Species Accession Gene Product
Brugia malayi Bm1_39765   Protein kinase domain containing protein
Caenorhabditis elegans CELE_W03G1.6   Protein PIG-1, isoform B
Echinococcus granulosus EgrG_000500200   maternal embryonic leucine zipper kinase
Echinococcus multilocularis EmuJ_000500200   maternal embryonic leucine zipper kinase
Homo sapiens ENSG00000165304   maternal embryonic leucine zipper kinase
Loa Loa (eye worm) LOAG_00732   CAMK/CAMKL/MELK protein kinase
Mus musculus ENSMUSG00000035683   maternal embryonic leucine zipper kinase
Schistosoma japonicum Sjp_0150020   gsx family homeobox protein; serine/threonine kinase
Schistosoma japonicum Sjp_0012410   ko:K08799 maternal embryonic leucine zipper kinase, putative
Schistosoma mansoni Smp_166150   serine/threonine kinase
Schmidtea mediterranea mk4.001893.00  
Trichomonas vaginalis TVAG_174020   CAMK family protein kinase
Trichomonas vaginalis TVAG_119830   CAMK family protein kinase
Trichomonas vaginalis TVAG_045990   CAMK family protein kinase

Essentiality

Bm1_39765 has one or more orthologs with essentiality data
Gene/Ortholog Organism Phenotype Source Study
CELE_W03G1.6 Caenorhabditis elegans larval lethal wormbase
Show/Hide essentiality data references
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Homo sapiens maternal embryonic leucine zipper kinase Compounds References
By sequence similarity to non orthologous druggable targets
Species Target Length Identity Alignment span Linked Drugs Reference
Homo sapiens Cyclin-dependent kinase 1/cyclin B1 297 aa 27.5% 287 aa Compounds References
Rattus norvegicus Cell division protein kinase 5 292 aa 24.5% 290 aa Compounds References
Rattus norvegicus Mitogen-activated protein kinase 1 358 aa 27.8% 291 aa Compounds References
Rattus norvegicus MAP kinase p38 alpha 360 aa 25.7% 331 aa Compounds References
Rattus norvegicus Mitogen-activated protein kinase 8 411 aa 26.5% 344 aa Compounds References
Plasmodium falciparum (isolate 3D7) Cell division control protein 2 homolog 288 aa 27.6% 293 aa Compounds References
Patiria pectinifera Cdc2 300 aa 26.0% 285 aa Compounds References
Rattus norvegicus Serine/threonine-protein kinase pim-3 326 aa 32.2% 267 aa Compounds References
Schizosaccharomyces pombe 972h- Casein kinase II subunit alpha 332 aa 24.2% 306 aa Compounds References
Obtained from network model

Ranking Plot

Putative Drugs List

Compound Raw Global Species
0.034 0.2701 0.2855
0.0386 0.2754 0.29
0.0398 0.2711 0.2899
0.7845 0.3584 0.8246
1.2723 0.466 0.4829
1.8594 0.5867 1
0.0412 0.2602 0.2785
0.0411 0.2772 0.2963
0.1032 0.6491 1
0.0403 0.2727 0.2805
0.0338 0.2696 0.2848
0.0351 0.2713 0.2895
1.058 0.8184 1
0.0412 0.2602 0.2785
0.7968 0.3238 1
0.0317 0.2574 0.2574
0.0373 0.2717 0.2885
0.0303 0.2687 0.2825
0.0409 0.2671 0.2839
0.0697 0.7736 0.5
0.037 0.2697 0.2858
2.2605 0.5746 1
0.0356 0.2706 0.2858
0.7845 0.3584 0.8246
0.2676 0.5059 1
0.0287 0.2518 0.2907
0.035 0.276 0.2888
0.0164 0.414 0.7411
0.0341 0.2733 0.3011
0.0341 0.2666 0.2829
0.051 0.3464 0.8436
0.037 0.2509 0.2492
0.0007 0.5 0.5
0.0411 0.2661 0.2831
0.0352 0.2737 0.2883
0.0351 0.2706 0.2858
0.0349 0.2705 0.2858
0.039106 0.297226 0.304736
0.0376 0.2669 0.2843
0.0408 0.2644 0.2855
0.0397 0.2751 1
0.0402 0.2685 0.2873
0.0365 0.2708 0.2858
0.0148 0.66 0.66
1.362 0.7095 0.7095
0.0657 0.6658 1
0.0565 0.4809 0.4809
0.2221 0.6256 1
0.0663 0.8727 1
0.0337 0.2704 0.2855
0.0871 0.6427 1
0.0033 1 1
0.0411 0.2791 0.2963
1.362 0.7095 0.7095
0.0417 0.2728 0.2906
0.0328 0.274 0.2908
1.362 0.7095 0.7095
0.2097 0.7607 0.8951
0.7968 0.3238 1
0.7845 0.3584 0.8246
0.0353 0.2708 0.2858
0.037 0.2708 0.2858
0.0378 0.2696 0.2859
1.362 0.7095 0.7095
0.7845 0.3584 0.8246
0.0254 0.2531 1
0.1831 0.2988 1
0.7845 0.3584 0.8246
0.0366 0.2715 0.2875
0.0415 0.2715 0.2872
0.034 0.2692 0.2855
1.362 0.7095 0.7095
0.0419 0.2733 0.2923
0.0378 0.2697 0.2858
0.0284 0.3381 0.7125
0.0365 0.2706 0.2858
0.1368 0.9745 1
0.037 0.2509 0.2492
0.0148 0.3428 0
0.0411 0.2862 0.3057
0.0285 0.6165 1
0.1802 0.8598 1
1.362 0.7095 0.7095
0.0342 0.2701 0.2855
0.0358 0.2714 0.2896
0.0349 0.2718 0.2858
0.0359 0.2726 0.2865
0.0351 0.2712 0.2894
0.0338 0.2621 0.2807
0.0324 0.2597 0.277
0.0328 0.2609 0.2768
0.0349 0.2705 0.2858
0.7845 0.3584 0.8246
0.037 0.2652 0.2859
0.0389 0.2693 0.2862
0.1019 0.7045 1
0.0419 0.2733 0.2923
0.0925 0.9858 1
0.3183 0.5015 1
0.1503 0.732 1
0.0395 0.2696 0.2867
0.0362 0.2728 0.2882
0.0302 0.2714 0.2898
1.1994 0.7415 0.7415
0.0027 1 1
0.0345 0.2692 0.285
0.3757 0.3624 0.3624
0.0369 0.2641 0.2855
0.0131 0.2632 0.2678
0.0272 0.5463 1
0.0871 0.6427 1
0.0349 0.2708 0.2858
0.0344 0.2562 0.2551
0.3757 0.3624 0.3624
0.0836 0.259 0.6039
0.7845 0.3584 0.8246
0.0356 0.2717 0.2877
0.0415 0.2715 0.2872
0.0398 0.2647 0.2647
0.1831 0.2988 1
0.0979 0.3048 1
0.0368 0.2678 0.285
0.0354 0.2806 0.299
0.0334 0.2614 0.2907
0.0336 0.2738 0.2904
0.0403 0.2756 0.2973
0.0353 0.2706 0.2858
0.069 0.2872 0.2934
0.034 0.2701 0.2855
2.4361 0.2945 0.6724
0.0344 0.2642 0.2853
0.0344 0.2692 0.2855
0.0355 0.2747 0.289
0.0148 0.3335 1
0.0412 0.2902 0.3099
0.0206 0.282 0.2999
0.0383 0.2531 0.2531
0.0007 0.5 0.5
0.0334 0.2658 0.2722
0.0359 0.2506 0.2842
0.7845 0.3584 0.8246
0.0327 0.2706 0.2908
0.0042 0.5 0.5
0.5943 0.2576 0.4429
0.0004 0.5 0.5
0.034 0.2625 0.281
0.0347 0.2531 0.2531
0.034 0.2701 0.2855
0.0324 0.2644 0.2847
0.0368 0.27 0.2858
0.0346 0.2686 0.284
1.362 0.7095 0.7095
0.0334 0.2658 0.2722
0.6421 0.5297 0
0.0416 0.2828 0.3017
0.0285 0.3508 1
0.026 0.7313 0.4676
0.0356 0.2708 0.2858
0.0321 0.3099 0.6454
0.0411 0.2661 0.2829
0.0277 0.3039 1
0.0348 0.2696 0.2861
0.0514 0.8633 1
0.0378 0.2697 0.2858
0.0357 0.2696 0.2864
2.1082 0.3983 0.3983
0.0349 0.2708 0.2858
0.036 0.27 0.2858
0.0803 0.8614 1
1.362 0.7095 0.7095
0.0148 0.6883 1
0.0358 0.253 0.2904
0.0011 1 1
0.0837 0.9916 1
0.0032 0.5 0.5
0.0365 0.2518 0.2858
0.0347 0.2808 0.2986
0.0373 0.2722 0.2722
0.0347 0.2708 0.2858
0.0381 0.2697 0.2881
0.0387 0.2785 0.2953
0.0411 0.2595 0.278
0.0356 0.2708 0.2858
0.0389479 0.314551 0.32147
0.0412 0.2624 0.2809
0.05416 0.252634 0.364532
0.0016 0.5 0.5
1.2558 0.6442 1
0.0413 0.2653 0.2822
0.0148 0.2872 0
0.0375 0.2708 0.2858
0.0333 0.2704 0.2855
0.0411 0.2658 0.2829
0.0365 0.2706 0.2858
0.036 0.27 0.2858
0.7845 0.3584 0.8246
1.8594 0.5867 1
0.0148 0.5715 0.5635
0.0039 0.9485 1
0.0373 0.2721 0.2858
0.7968 0.3238 1
0.0334 0.2755 0.2904
0.0059 1 1
0.4742 0.5115 1
0.0673 0.8388 1
0.0344 0.2708 0.2858
0.0337 0.2692 0.2855
0.034 0.2713 0.2866
0.0029 0.5 0.5
1.8594 0.5867 1
0.0383 0.2718 0.2899
0.0373 0.2619 0.2807
0.0335 0.251 0.2858
0.0925 0.9858 1
0.0392 0.2696 0.2866
0.0351 0.2713 0.2895
0.0063 1 1
0.1159 0.252 0.4769
0.0359 0.2506 0.2842
0.0373 0.27 0.2858
0.036 0.27 0.2858
1.058 0.8184 1
0.036 0.2696 0.2858
0.0338 0.2512 0.2858
0.1032 0.6491 1
0.0359 0.2726 0.2865
0.0349 0.2677 0.2826
0.0335 0.2704 0.2855
0.034 0.2694 0.287
0.040244 0.297437 0.300187
0.0365 0.2725 0.2904
0.0836 0.259 0.6039
0.0353 0.2705 0.2858
0.0407 0.2693 0.2867
0.0403 0.27 0.2864
0.0897 0.9859 1
0.0352 0.2613 0.2833
0.0353 0.2745 0.2921
0.0355 0.273 0.2728
0.0353 0.2721 0.2858
0.0342 0.2701 0.2855
0.0802 0.9429 1
0.0284 0.3664 1
0.0368 0.272 0.2902
0.0063 0.7244 0
0.034 0.2708 0.2858
0.0438114 0.297437 0.302149
0.0412 0.2664 0.2833
0.0416 0.2828 0.3017
0.036 0.2714 0.2883
0.0417 0.2834 0.2995
0.036 0.2704 0.2855
0.0378 0.2696 0.2859
0.0355 0.269 0.2905
0.0403 0.2756 0.2973
1.362 0.7095 0.7095
0.0486 0.709 1
0.5158 0.5977 1
0.917 0.8256 1
0.0148 0.7202 1
1.7046 0.4071 0.4071
1.2723 0.466 0.4829
0.0358 0.2706 0.2858
0.0396 0.2857 0.2983
0.0413 0.2804 0.2972
0.0373 0.27 0.2858
0.1831 0.2988 1
0.0397 0.419 1
0.0394504 0.299954 0.304767
0.0347 0.2531 0.2531
0.0411 0.2621 0.2807
0.0459182 0.30876 0.316598
0.0333 0.2677 0.2855
0.0388 0.2669 0.2728
0.0373 0.2717 0.2885
0.0335 0.259 0.2572
0.0567 0.3297 1
0.0344 0.2692 0.2855
0.0364 0.271 0.2862
0.0355 0.2747 0.289
0.037 0.2718 0.2858
0.0098 0.3752 0.7088
0.0081 1 1
0.0417 0.2834 0.2995
1.362 0.7095 0.7095
0.0273 0.319 1
0.7845 0.3584 0.8246
0.034 0.2694 0.287
0.0347 0.2705 0.2858
0.0347 0.2708 0.2858
0.1487 0.4367 1
0.1831 0.2988 1
0.2221 0.6256 1
0.0386 0.2743 0.2929
0.0588 0.2653 0.2653
0.1503 0.732 1
0.0344 0.274 0.2923
0.036 0.2706 0.2858
0.0148 0.4751 0
0.0358 0.2717 0.2858
0.0356 0.2708 0.2858
0.0373 0.2697 0.2858
0.0333 0.2701 0.2855
1.362 0.7095 0.7095
0.0414 0.271 0.2895
0.0383 0.2706 0.2858
0.0414 0.2667 0.2848
0.0397 0.2693 0.2864
0.7845 0.3584 0.8246
0.8114 0.9988 1
0.0353 0.2745 0.2921
0.0363 0.2718 0.2858
0.7845 0.3584 0.8246
0.0023 0.5 0.5
0.035 0.276 0.2888
0.036 0.3814 1
0.0417 0.2834 0.2995
1.8594 0.5867 1
0.0016 0.5 0.5
0.0056 1 1
0.0337 0.2701 0.2855
0.0368 0.2697 0.2858
0.0365 0.2706 0.2858
0.0351 0.2705 0.2858
0.0411 0.2621 0.2807
0.0148 0.3433 0
0.0359 0.2506 0.2842
0.0039 0.5 0.5
0.0411 0.269 0.2877
0.0302 0.253 0.2504
0.0347 0.2708 0.2858
0.0353 0.2697 0.2858
0.0347 0.2637 0.2836
1.362 0.7095 0.7095
0.0008 0.5 0.5
0.0012 0.5 0.5
0.0375 0.2706 0.2858
0.0012 0.5 0.5
0.0345 0.2692 0.285
0.0383 0.6905 1
0.917 0.8256 1
0.5943 0.2576 0.4429
0.0403 0.2706 0.2872
0.0301 0.2783 0.2943
0.0148 0.8081 0.8081
0.0402 0.2706 0.2872
0.0374 0.2703 0.2853
0.0285 0.325 0.6173
0.0792 0.9836 1
0.0148 0.4425 0.4425
0.0416 0.266 0.2837
0.0148 0.7057 0.6874
0.0347 0.2808 0.2986
0.0362 0.2694 0.2859
0.2097 0.7607 0.8951
1.362 0.7095 0.7095
0.3468 0.5882 0.6161
0.0776 0.9577 1
0.0374 0.2696 0.2862
0.0408 0.2705 0.287
0.0389 0.2693 0.2866
0.0148 0.8397 0
0.036 0.2697 0.2858
0.0353 0.2721 0.2858
0.0067 0.5 0.5
0.0409666 0.297437 0.302149
0.0397 0.2763 0.2933
0.0386 0.2708 0.2689
0.0349 0.2706 0.2858
0.026 0.8149 1
0.036 0.2697 0.2858
0.3757 0.3624 0.3624
0.0362 0.269 0.2859
0.0351 0.2712 0.2894
0.036 0.2714 0.2896
0.0344 0.2701 0.2855
0.7968 0.3238 1
0.0347 0.2808 0.2986
0.0075 0.2515 0.5766
0.036 0.2714 0.2896
0.0381 0.2697 0.2881
0.037 0.2696 0.2858
0.7681 0.5386 1
0.0565 0.711 1
1.2558 0.6442 1
0.0411 0.2661 0.2829
0.038 0.2519 0.2519
0.0321 0.2682 0.2884
0.0393 0.2665 0.284
0.0286 0.3875 1
0.0335 0.2701 0.2855
0.0286 0.3497 0.74
0.022 0.3859 0.7181
0.7968 0.3238 1
0.0206 0.282 0.2999
0.0363 0.2706 0.2858
0.0357 0.2696 0.2864
0.0363 0.2706 0.2858
0.0376 0.2621 0.2807
0.0061 0.6883 0.6808
0.0148 0.6883 1
0.2097 0.7607 0.8951
0.0375 0.273 0.273
0.0336 0.2687 0.2875
0.0398 0.2705 0.2867
0.067 0.9984 1
0.0379 0.2636 0.2836
0.0037 1 0.5
0.0375 0.2697 0.2858
0.0344 0.2701 0.2855
0.0577 0.2641 0.2613
0.7845 0.3584 0.8246
0.0397 0.261 0.261
0.0148 0.2747 0
0.04 0.2661 0.2829
0.0148 0.5851 0.5656
0.2338 0.9371 1
0.0607 0.2598 0.2692
0.0381 0.2696 0.2879
0.0378 0.2696 0.2864
0.0148 0.7076 0.7008
0.0373 0.2754 0.2945
0.0412 0.2624 0.2809
0.034 0.2701 0.2855
0.0485 0.41 0.7379
0.0405 0.2665 0.2841
0.034 0.2739 0.2923
0.0412 0.2781 0.2968
0.0286 0.3875 1
0.0344 0.2701 0.2855
0.0286 0.3469 1
0.917 0.8256 1
0.0411 0.2645 0.2831
0.0033 0.5 0.5
0.0353 0.2706 0.2858
0.0098 0.3242 0.2614
0.0351 0.2706 0.2858
0.0353 0.2676 0.2845
0.0359 0.2506 0.2842
0.1335 0.819 1
0.0334 0.2835 0.303
0.0227 0.2685 0.288
0.0335 0.2704 0.2855
0.0233 0.3834 1
0.0411 0.2621 0.2807
0.0018 0.5 0.5
0.0389 0.2744 0.2929
0.3757 0.3624 0.3624
0.7845 0.3584 0.8246
0.037 0.2658 0.2829
0.036 0.27 0.2858
0.625 0.7273 1
0.0382 0.2729 0.2903
0.5628 0.8647 1
0.0411 0.2772 0.2963
0.0353 0.2696 0.2858
0.7845 0.3584 0.8246
0.0411 0.2621 0.2807
0.0504 0.8939 1
0.0344 0.2793 0.2912
0.0347 0.2718 0.2858
0.076 0.7401 1
0.0341 0.269 0.2859
0.0347 0.2808 0.2986
0.0032 0.5 0.5
0.0395 0.2705 0.2867
0.7968 0.3238 1
1.8594 0.5867 1
0.0589 0.2661 0.2651
0.0343 0.2701 0.2855
0.0281 0.4019 0.4019
0.037 0.27 0.2858
0.0736 0.9839 1
0.0206 0.282 0.2999
0.0347 0.2706 0.2858
0.0345 0.2692 0.285
0.0337 0.2701 0.2855
0.0368 0.272 0.2902
0.0415 0.2715 0.2872
0.0351 0.2706 0.2858
0.1831 0.2988 1
0.6221 0.5335 1
0.7968 0.3238 1
0.0389 0.2699 0.2866
0.0412 0.2602 0.2785
0.0353 0.2708 0.2858
0.0378 0.2697 0.2858
0.7845 0.3584 0.8246
2.5406 0.2824 1
0.036 0.2714 0.2883
0.037 0.27 0.2858
0.0411 0.2802 0.2995
0.0383 0.2698 0.2881
0.3183 0.5015 1
0.039 0.266 0.2859
0.0405 0.2665 0.2841
0.0363 0.2706 0.2858
0.0368 0.2714 0.2896
0.0395 0.2696 0.2867
0.0414 0.2702 0.2885
0.0349 0.2708 0.2858
0.0344 0.2699 0.2859
0.4742 0.5115 1
0.0362 0.269 0.2859
0.0365 0.2708 0.2858
0.0373 0.2717 0.2885
0.1487 0.4367 1
0.0284 0.3222 1
0.6421 0.5297 0
0.1831 0.2988 1
0.0344 0.2692 0.2855
0.026 0.7313 0.4676
0.3757 0.3624 0.3624
0.0871 0.6427 1
0.3757 0.3624 0.3624
0.0342 0.2701 0.2855
0.0736 0.9839 1
0.0331 0.267 0.2829
0.0836 0.259 0.6039
0.0411 0.2621 0.2807
0.0411 0.2652 0.2842
0.051 0.3464 0.8436
0.0416 0.2776 0.2966
0.0358 0.2706 0.2858
0.0431 0.3499 0.3746
0.0066 0.3101 0
0.0389 0.2699 0.2866
0.0361 0.27 0.2859
0.0381 0.2701 0.2883
0.0422 0.4365 0.5707
0.0696 0.8399 1
0.0342 0.2519 0.2501
0.028 0.284 0.4909
0.0088 0.4477 0.4477
0.0393 0.2693 0.2858
0.0403 0.2756 0.2973
0.7845 0.3584 0.8246
0.0286 0.3535 1
0.0345 0.2678 0.2839
0.0401 0.2693 0.2866
0.0915 0.4885 0.4885
0.0333 0.2704 0.2855
0.0383 0.2697 0.2856
0.0373 0.2697 0.2858
0.0148 0.7527 1
0.7963 0.5704 0.5704
0.0383 0.2706 0.2858
0.0381 0.2701 0.2883
0.0368 0.264 0.2836
0.0396 0.2625 0.281
0.0395 0.2705 0.2867
0.7968 0.3238 1
0.0342 0.2542 0.2858
0.0359 0.2506 0.2842
0.0247 0.2726 1
0.0354 0.2806 0.299
0.0059 1 1
0.0375 0.2686 0.2853
0.0375 0.2718 0.2858
1.2558 0.6441 1
0.0026 0.5 0.5
0.0321 0.3099 0.6454
0.041 0.2667 0.2899
0.0012 0.5 0.5
0.0411 0.2621 0.2807
0.0347 0.2708 0.2858
0.7968 0.3238 1
0.0353 0.2697 0.2858
0.0347 0.2718 0.2858
0.034 0.2708 0.2858
0.0363 0.2718 0.2899
1.362 0.7095 0.7095
0.0376 0.2686 0.2836
0.0349 0.2789 0.2966
0.0281 0.429 1
0.0415 0.2715 0.2872
0.0363 0.2714 0.2894
0.0413 0.2633 0.2815
0.0684 0.2719 0.2717
0.0303 0.2687 0.2825
0.0412 0.2676 0.2833
0.0351 0.2725 0.2904
0.0378 0.2696 0.2879
0.0915 0.4885 0.4885
0.0349 0.27 0.2858
0.0389 0.2699 0.2866
0.0253 0.2553 1
1.362 0.7095 0.7095
0.0349 0.27 0.2858
0.1111 0.2718 1
0.0351 0.2706 0.2858
0.034 0.2685 0.2841
0.0383 0.2706 0.2858
0.0343 0.2757 0.2934
0.0263 0.6261 1
0.0356 0.2745 0.2921
0.0564 0.6726 1
0.1159 0.252 0.4769
0.0282 0.5178 1
0.0356 0.2698 0.2878
0.0344 0.271 0.2892
0.0701 0.2898 0.3013
0.625 0.7273 1
0.034 0.2742 0.2904
0.0415 0.2715 0.2872
0.2338 0.9371 1
0.0148 0.3428 0
0.0381 0.2924 0.3113
0.5943 0.2576 0.4429
0.0386 0.2541 0.2541
0.0377 0.2732 0.2888
0.0352 0.2625 0.281
0.0411 0.2621 0.2807
0.033 0.2632 0.2815
0.0333 0.2714 0.2896
0.3757 0.3624 0.3624
0.7681 0.5386 1
0.0373 0.274 0.2916
0.3757 0.3624 0.3624
0.0386 0.2842 0.3022
0.0392 0.2641 0.2855
1.5417 0.6263 1
0.0381 0.2706 0.2858
0.0284 0.3222 1
0.0358 0.2706 0.2858
0.0373 0.274 0.2916
0.3757 0.3624 0.3624
0.0344 0.2692 0.2855
0.1308 0.3729 0.4508
0.0344 0.2701 0.2855
0.0347 0.2708 0.2858
0.3183 0.5015 1
0.0081 0.5 0.5
0.0419 0.2733 0.2923
0.0411 0.2687 0.2875
0.0341 0.2638 0.2629
1.8594 0.5867 1
0.0359 0.264 0.2821
0.0196 0.3166 0.4055
0.0353 0.2681 0.2858
0.0357 0.2759 0.2938
0.0148 0.4803 0
0.0693 0.2506 0.2798
0.0347 0.2708 0.2858
0.0302 0.2714 0.2898
0.039 0.266 0.2859
0.0344 0.2692 0.2855
0.0347 0.2808 0.2986
0.0802 0.9429 1
0.034 0.2708 0.2858
0.0389 0.2693 0.2866
0.0359 0.2506 0.2842
0.0392 0.2692 0.2863
0.0349 0.2625 0.281
0.0093 0.8828 0
1.2558 0.6442 1
1.8594 0.5867 1
0.917 0.8256 1
0.7681 0.5386 1
0.0336 0.2669 0.2793
0.0415 0.2715 0.2872
0.0351 0.2742 0.2904
0.1831 0.2988 1
0.0337 0.2701 0.2855
0.0773 0.7845 1
0.0278 0.3075 1
0.0411 0.2621 0.2807
0.0349 0.2705 0.2858
0.0365 0.2706 0.2858
0.038 0.4626 1
0.0342 0.27 0.2858
1.8594 0.5867 1
0.0359 0.2635 0.2836
0.0092 1 1
0.0336 0.2669 0.2793
1.8594 0.5867 1
0.0375 0.2659 0.2859
0.7845 0.3584 0.8246
1.2558 0.6442 1
0.0364 0.2729 0.2883
1.1994 0.7415 0.7415
0.0351 0.2718 0.2895
0.036 0.2712 0.2894
0.0353 0.2705 0.2858
0.0242713 0.304271 0.310059
0.0955 0.2795 1
0.0276 0.3219 0.5922
0.0003 0.5 0.5
0.0333 0.2677 0.2855
0.0059 1 1
0.0382 0.2729 0.2903
0.0362 0.2758 0.2929
0.0393 0.2607 0.278
0.0381 0.2718 0.2899
1.058 0.8184 1
0.0347 0.2708 0.2858
0.0412 0.2783 0.2949
0.0373 0.2721 0.2858
0.0692523 0.255933 0.261428
0.0007 0.5 0.5
0.1099 0.4327 1
0.0395 0.2696 0.2867
0.0356 0.2714 0.2896
0.0411 0.2621 0.2807
0.0351 0.2718 0.2858
0.0039 0.5 0.5
0.0416 0.2828 0.3017
0.0148 0.4654 0.4654
0.0353 0.2728 0.2795
0.0564 0.7838 1
0.1159 0.252 0.4769
1.362 0.7095 0.7095
0.0419 0.2733 0.2923
0.0411 0.2687 0.2875
0.0368 0.2694 0.2858
0.0937 0.4217 1
0.0347 0.2706 0.2858
1.362 0.7095 0.7095
0.0347 0.2733 0.2871
1.8594 0.5867 1
0.0148 0.7057 0.6874
0.0347 0.253 0.2711
0.5158 0.5977 1
0.0285 0.406 1
0.034 0.2708 0.2858
0.0411 0.2621 0.2807
0.0336 0.2524 0.2506
1.5417 0.6263 1
0.0411 0.2709 0.2898
0.0871 0.6427 1
0.7968 0.3238 1
0.034 0.2543 0.2543
0.0036 0.5 0.5
0.0351 0.2706 0.2858
0.0346 0.2567 0.2862
0.0196 0.3166 0.4055
0.036 0.2721 0.2858
0.034 0.2692 0.2855
0.0322 0.2579 0.2579
1.2558 0.6442 1
0.0415 0.2715 0.2872
1.8594 0.5867 1
0.7968 0.3238 1
0.0397 0.266 0.2841
0.0062 0.6935 0.7231
0.027 0.4229 1
0.0375 0.2706 0.2858
0.0347 0.2708 0.2858
0.7845 0.3584 0.8246
0.0343 0.2757 0.2934
0.3757 0.3624 0.3624
0.3757 0.3624 0.3624
0.2097 0.7607 0.8951
0.0979 0.3048 1
0.0429 0.5283 1
0.917 0.8256 1
0.0329 0.2688 0.2902
0.0064 0.3377 0.3377
0.0349 0.2706 0.2858
0.0935 0.986 1
0.0022 0.5 0.5
0.1159 0.252 0.4769
0.0419 0.2733 0.2923
0.0416 0.271 0.2856
0.0353 0.2757 0.2936
0.0387 0.2696 0.2866
0.0091 1 1
0.0381 0.2707 0.2862
0.0395 0.2696 0.2867
0.0373 0.2697 0.2858
0.0349 0.2708 0.2858
0.0426273 0.297437 0.302149
0.0397 0.276 0.2931
0.037 0.2708 0.2858
0.0069 0.3067 0.9179
0.0353 0.2713 0.2895
0.0349 0.2706 0.2858
0.0366 0.2634 0.2817
0.0347 0.2644 0.2824
0.0303 0.2687 0.2825
0.0337 0.2681 0.2886
0.0413 0.2638 0.2819

Assayability

Assay information

No assay information for this target.

Reagent availability

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Gene identifier Bm1_39765 (Brugia malayi), Protein kinase domain containing protein
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