Detailed view for Bm1_00290

Basic information

TDR Targets ID: 244129
Brugia malayi, Zinc finger, C2H2 type family protein

Source Database / ID:  GenBank

pI: 9.3176 | Length (AA): 323 | MW (Da): 37866 | Paralog Number: 7

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG1

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00096   Zinc finger, C2H2 type
PF13894   C2H2-type zinc finger

Gene Ontology

Mouse over links to read term descriptions.
GO:0005622   intracellular  
GO:0008270   zinc ion binding  
GO:0003676   nucleic acid binding  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

There are 4 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
169 323 2i13 (A) 31 184 46.00 0 1 0.906276 1.03
211 243 2epz (A) 500 532 52.00 0.00032 0.5 0.758567 -0.97
211 243 2emg (A) 8 40 52.00 0.0014 0.36 0.730567 -0.83
239 271 2ena (A) 8 40 61.00 0.000012 0.95 0.862567 -0.66

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_126539)

Species Accession Gene Product
Arabidopsis thaliana AT3G29340   C2H2-type zinc finger protein
Brugia malayi Bm1_29545   Zinc finger, C2H2 type family protein
Brugia malayi Bm1_07095   Zinc finger, C2H2 type family protein
Brugia malayi Bm1_18085   Zinc finger, C2H2 type family protein
Brugia malayi Bm1_54340   Zinc finger, C2H2 type family protein
Brugia malayi Bm1_29530   Zinc finger, C2H2 type family protein
Brugia malayi Bm1_18090   Zinc finger, C2H2 type family protein
Brugia malayi Bm1_00290   Zinc finger, C2H2 type family protein
Brugia malayi Bm1_54345   Zinc finger, C2H2 type family protein
Candida albicans CaO19.3928   Zn finger orf
Candida albicans CaO19.11410   Zn finger orf
Candida albicans CaO19.4125   similar to S. cerevisiae PZF1 (YPR186C) RNA Pol III transcription initiation factor TFIIIA
Caenorhabditis elegans CELE_ZK616.10   Protein EHN-3, isoform A
Caenorhabditis elegans CELE_Y55F3AM.14   Protein Y55F3AM.14
Cryptosporidium hominis Chro.20127   hypothetical protein
Cryptosporidium parvum cgd2_1150   hypothetical protein
Drosophila melanogaster Dmel_CG14938   crooked legs
Echinococcus granulosus EgrG_001187100   zinc finger protein 91
Echinococcus granulosus EgrG_000489800   zinc finger protein
Echinococcus granulosus EgrG_001123200   zinc finger protein
Echinococcus granulosus EgrG_001006800   zinc finger C2H2 type
Echinococcus multilocularis EmuJ_000111800   zinc finger protein 236
Echinococcus multilocularis EmuJ_000854300   zinc finger, C2H2 type
Echinococcus multilocularis EmuJ_001123200   zinc finger protein
Echinococcus multilocularis EmuJ_000308300  
Echinococcus multilocularis EmuJ_000859200   zinc finger protein 333
Homo sapiens 148206   zinc finger protein 714
Homo sapiens ENSG00000196437   zinc finger protein 569
Homo sapiens ENSG00000189042   zinc finger protein 567
Homo sapiens 345462   zinc finger protein 879
Homo sapiens ENSG00000167380   zinc finger protein 226
Homo sapiens ENSG00000170631   zinc finger protein 16
Homo sapiens ENSG00000197385   zinc finger protein 860
Homo sapiens 57336   zinc finger protein 287
Homo sapiens ENSG00000159915   zinc finger protein 233
Homo sapiens ENSG00000197016   zinc finger protein 470
Homo sapiens 400682   zinc finger protein 100-like
Homo sapiens ENSG00000269343   zinc finger protein 587B
Homo sapiens 101928641   zinc finger protein 816-like
Homo sapiens ENSG00000083817   zinc finger protein 416
Homo sapiens ENSG00000160336   zinc finger protein 761
Homo sapiens ENSG00000188868   zinc finger protein 563
Homo sapiens ENSG00000131845   zinc finger protein 304
Homo sapiens ENSG00000198939   ZFP2 zinc finger protein
Homo sapiens ENSG00000102870   zinc finger protein 629
Homo sapiens ENSG00000213020   zinc finger protein 611
Homo sapiens ENSG00000178386   zinc finger protein 223
Homo sapiens ENSG00000251247   zinc finger protein 345
Homo sapiens ENSG00000198040   zinc finger protein 84
Homo sapiens ENSG00000156853   zinc finger protein 689
Homo sapiens ENSG00000159885   zinc finger protein 222
Homo sapiens ENSG00000185869   zinc finger protein 829
Homo sapiens ENSG00000176293   zinc finger protein 135
Homo sapiens 147694   zinc finger protein 548
Homo sapiens ENSG00000184635   zinc finger protein 93
Homo sapiens ENSG00000197779   zinc finger protein 81
Homo sapiens 101060810   zinc finger protein 492-like
Homo sapiens ENSG00000183850   zinc finger protein 730
Homo sapiens ENSG00000197619   zinc finger protein 615
Homo sapiens ENSG00000198028   zinc finger protein 560
Homo sapiens ENSG00000186230   zinc finger protein 749
Homo sapiens 102724436   zinc finger protein 93-like
Homo sapiens ENSG00000197857   zinc finger protein 44
Homo sapiens ENSG00000178917   zinc finger protein 852
Homo sapiens ENSG00000196378   zinc finger protein 34
Homo sapiens ENSG00000196247   zinc finger protein 107
Homo sapiens ENSG00000263002   zinc finger protein 234
Homo sapiens ENSG00000198440   zinc finger protein 583
Homo sapiens ENSG00000278318   zinc finger protein 229
Homo sapiens ENSG00000198453   zinc finger protein 568
Homo sapiens 342909   zinc finger protein 284
Homo sapiens ENSG00000161298   zinc finger protein 382
Homo sapiens ENSG00000166704   zinc finger protein 606
Homo sapiens 7757   zinc finger protein 208
Homo sapiens ENSG00000185177   zinc finger protein 479
Homo sapiens ENSG00000197937   zinc finger protein 347
Homo sapiens ENSG00000167766   zinc finger protein 83
Homo sapiens ENSG00000258405   zinc finger protein 578
Homo sapiens ENSG00000171291   zinc finger protein 439
Homo sapiens ENSG00000274349   zinc finger protein 658
Homo sapiens ENSG00000196597   zinc finger protein 782
Homo sapiens ENSG00000176222   zinc finger protein 404
Homo sapiens ENSG00000198169   zinc finger protein 251
Homo sapiens 7733   zinc finger protein 180
Homo sapiens ENSG00000174586   zinc finger protein 497
Homo sapiens ENSG00000196458   zinc finger protein 605
Homo sapiens ENSG00000256229   zinc finger protein 486
Homo sapiens ENSG00000188171   zinc finger protein 626
Homo sapiens ENSG00000242852   zinc finger protein 709
Homo sapiens 170960   zinc finger protein 721
Homo sapiens ENSG00000197608   zinc finger protein 841
Homo sapiens ENSG00000142065   ZFP14 zinc finger protein
Homo sapiens ENSG00000131115   zinc finger protein 227
Homo sapiens ENSG00000167562   zinc finger protein 701
Homo sapiens ENSG00000131849   zinc finger protein 132
Homo sapiens ENSG00000096654   zinc finger protein 184
Homo sapiens ENSG00000197020   zinc finger protein 100
Homo sapiens ENSG00000196350   zinc finger protein 729
Homo sapiens ENSG00000204519   zinc finger protein 551
Homo sapiens ENSG00000196670   ZFP62 zinc finger protein
Homo sapiens ENSG00000105750   zinc finger protein 85
Homo sapiens ENSG00000146757   zinc finger protein 92
Homo sapiens ENSG00000197863   zinc finger protein 790
Homo sapiens ENSG00000198538   zinc finger protein 28
Homo sapiens ENSG00000182141   zinc finger protein 708
Homo sapiens ENSG00000124459   zinc finger protein 45
Homo sapiens ENSG00000198466   zinc finger protein 587
Homo sapiens 390980   zinc finger protein 805
Homo sapiens ENSG00000147118   zinc finger protein 182
Homo sapiens ENSG00000197134   zinc finger protein 257
Homo sapiens ENSG00000198342   zinc finger protein 442
Homo sapiens ENSG00000176024   zinc finger protein 613
Homo sapiens ENSG00000198182   zinc finger protein 607
Homo sapiens 101929991   putative zinc finger protein 66-like
Homo sapiens ENSG00000153896   zinc finger protein 599
Homo sapiens ENSG00000197123   zinc finger protein 679
Homo sapiens ENSG00000197054   zinc finger protein 763
Homo sapiens ENSG00000196967   zinc finger protein 585A
Homo sapiens ENSG00000147789   zinc finger protein 7
Homo sapiens ENSG00000187187   zinc finger protein 546
Homo sapiens 58491   zinc finger protein 71
Homo sapiens ENSG00000180626   zinc finger protein 594
Homo sapiens ENSG00000257446   zinc finger protein 878
Homo sapiens ENSG00000182986   zinc finger protein 320
Homo sapiens ENSG00000118620   zinc finger protein 430
Homo sapiens ENSG00000171295   zinc finger protein 440
Homo sapiens ENSG00000267041   zinc finger protein 850
Homo sapiens ENSG00000128000   zinc finger protein 780B
Homo sapiens 7728   zinc finger protein 175
Homo sapiens ENSG00000136870   zinc finger protein 189
Homo sapiens ENSG00000106261   zinc finger with KRAB and SCAN domains 1
Homo sapiens 440515   zinc finger protein 506
Homo sapiens ENSG00000198633   zinc finger protein 534
Homo sapiens ENSG00000180479   zinc finger protein 571
Homo sapiens ENSG00000180855   zinc finger protein 443
Homo sapiens ENSG00000186777   zinc finger protein 732
Homo sapiens ENSG00000196152   zinc finger protein 79
Homo sapiens ENSG00000272968   RBAK-RBAKDN readthrough
Homo sapiens 100529240   ZNF816-ZNF321P readthrough
Homo sapiens 100129842   zinc finger protein 737
Homo sapiens 9831   zinc finger protein 623
Homo sapiens 7768   zinc finger protein 225
Homo sapiens 388559   zinc finger protein 888
Homo sapiens ENSG00000178229   zinc finger protein 543
Homo sapiens ENSG00000181007   ZFP82 zinc finger protein
Homo sapiens 102724693   zinc finger protein 718-like
Homo sapiens ENSG00000189164   zinc finger protein 527
Homo sapiens ENSG00000197302   zinc finger protein 720
Homo sapiens ENSG00000197050   zinc finger protein 420
Homo sapiens ENSG00000180257   zinc finger protein 816
Homo sapiens ENSG00000254004   zinc finger protein 260
Homo sapiens ENSG00000198429   zinc finger protein 69
Homo sapiens ENSG00000214022   replication initiator 1
Homo sapiens ENSG00000256087   zinc finger protein 432
Homo sapiens ENSG00000256683   zinc finger protein 350
Homo sapiens ENSG00000152443   zinc finger protein 776
Homo sapiens 7643   zinc finger protein 90
Homo sapiens ENSG00000249709   zinc finger protein 564
Homo sapiens 162966   zinc finger protein 600
Homo sapiens ENSG00000167637   zinc finger protein 283
Homo sapiens ENSG00000269699   zinc finger, imprinted 2
Homo sapiens ENSG00000196357   zinc finger protein 565
Homo sapiens ENSG00000170954   zinc finger protein 415
Homo sapiens ENSG00000189144   zinc finger protein 573
Homo sapiens ENSG00000005801   zinc finger protein 195
Homo sapiens 101060181   zinc finger protein ZnFP12-like
Homo sapiens ENSG00000171827   zinc finger protein 570
Homo sapiens ENSG00000062370   zinc finger protein 112
Homo sapiens ENSG00000142556   zinc finger protein 614
Homo sapiens 163087   zinc finger protein 383
Homo sapiens 90321   zinc finger protein 766
Homo sapiens ENSG00000197044   zinc finger protein 441
Homo sapiens 101927749   zinc finger protein 25-like
Homo sapiens ENSG00000196172   zinc finger protein 681
Homo sapiens 339500   zinc finger protein 678
Homo sapiens 100131827   zinc finger protein 717
Homo sapiens ENSG00000197372   zinc finger protein 675
Homo sapiens ENSG00000152926   zinc finger protein 117
Homo sapiens ENSG00000173258   zinc finger protein 483
Homo sapiens ENSG00000185947   zinc finger protein 267
Homo sapiens ENSG00000159882   zinc finger protein 230
Homo sapiens ENSG00000121406   zinc finger protein 549
Homo sapiens ENSG00000267680   zinc finger protein 224
Homo sapiens ENSG00000145908   zinc finger protein 300
Homo sapiens ENSG00000142528   zinc finger protein 473
Homo sapiens ENSG00000196345   zinc finger with KRAB and SCAN domains 7
Homo sapiens ENSG00000127903   zinc finger protein 835
Homo sapiens ENSG00000105708   zinc finger protein 14
Homo sapiens ENSG00000204604   zinc finger protein 468
Homo sapiens ENSG00000167377   zinc finger protein 23
Homo sapiens 388523   zinc finger protein 728
Homo sapiens 101059906   collagen alpha-2(VI) chain-like
Homo sapiens ENSG00000245680   zinc finger protein 585B
Homo sapiens ENSG00000196109   zinc finger protein 676
Homo sapiens ENSG00000197808   zinc finger protein 461
Homo sapiens ENSG00000132010   zinc finger protein 20
Homo sapiens ENSG00000204611   zinc finger protein 616
Homo sapiens ENSG00000198464   zinc finger protein 480
Homo sapiens ENSG00000182111   zinc finger protein 716
Homo sapiens ENSG00000196653   zinc finger protein 502
Homo sapiens ENSG00000196757   zinc finger protein 700
Homo sapiens ENSG00000152454   zinc finger protein 256
Homo sapiens ENSG00000130844   zinc finger protein 331
Homo sapiens ENSG00000197714   zinc finger protein 460
Homo sapiens 79788   zinc finger protein 665
Homo sapiens ENSG00000196646   zinc finger protein 136
Homo sapiens 10795   zinc finger protein 268
Homo sapiens 163049   zinc finger protein 791
Homo sapiens ENSG00000196417   zinc finger protein 765
Homo sapiens ENSG00000196263   zinc finger protein 471
Homo sapiens ENSG00000173480   zinc finger protein 417
Homo sapiens ENSG00000130684   zinc finger protein 337
Homo sapiens ENSG00000198093   zinc finger protein 649
Homo sapiens ENSG00000083844   zinc finger protein 264
Homo sapiens 126017   zinc finger protein 813
Homo sapiens ENSG00000197782   zinc finger protein 780A
Homo sapiens 10793   zinc finger protein 273
Homo sapiens ENSG00000081386   zinc finger protein 510
Homo sapiens ENSG00000120784   ZFP30 zinc finger protein
Homo sapiens 730291   zinc finger protein 735
Homo sapiens ENSG00000197933   zinc finger protein 823
Homo sapiens ENSG00000198185   zinc finger protein 334
Homo sapiens ENSG00000196867   ZFP28 zinc finger protein
Homo sapiens ENSG00000169981   zinc finger protein 35
Homo sapiens ENSG00000178935   zinc finger protein 552
Homo sapiens ENSG00000147124   zinc finger protein 41
Homo sapiens ENSG00000184939   ZFP90 zinc finger protein
Homo sapiens ENSG00000221994   zinc finger protein 630
Homo sapiens ENSG00000196268   zinc finger protein 493
Homo sapiens ENSG00000175691   zinc finger protein 77
Homo sapiens ENSG00000197472   zinc finger protein 695
Homo sapiens ENSG00000196724   zinc finger protein 418
Homo sapiens ENSG00000186272   zinc finger protein 17
Homo sapiens 7700   zinc finger protein 141
Homo sapiens ENSG00000173041   zinc finger protein 680
Homo sapiens ENSG00000180035   zinc finger protein 48
Homo sapiens ENSG00000213096   zinc finger protein 254
Homo sapiens ENSG00000196150   zinc finger protein 250
Homo sapiens ENSG00000198131   zinc finger protein 544
Homo sapiens 56242   zinc finger protein 253
Homo sapiens ENSG00000171817   zinc finger protein 540
Homo sapiens ENSG00000159917   zinc finger protein 235
Homo sapiens ENSG00000189180   zinc finger protein 33A
Homo sapiens ENSG00000177932   zinc finger protein 354C
Homo sapiens 730087   zinc finger protein 726
Homo sapiens ENSG00000198521   zinc finger protein 43
Homo sapiens ENSG00000186300   zinc finger protein 555
Homo sapiens ENSG00000197647   zinc finger protein 433
Homo sapiens ENSG00000196267   zinc finger protein 836
Homo sapiens 101929206   zinc finger protein 254-like
Homo sapiens ENSG00000168661   zinc finger protein 30
Homo sapiens ENSG00000127081   zinc finger protein 484
Homo sapiens 57474   zinc finger protein 490
Homo sapiens ENSG00000197013   zinc finger protein 429
Homo sapiens ENSG00000146587   RB-associated KRAB zinc finger
Homo sapiens ENSG00000170949   zinc finger protein 160
Homo sapiens 102725136   putative zinc finger protein ENSP00000328166-like
Homo sapiens ENSG00000197928   zinc finger protein 677
Homo sapiens ENSG00000197360   zinc finger protein 98
Homo sapiens ENSG00000167555   zinc finger protein 528
Homo sapiens ENSG00000159905   zinc finger protein 221
Homo sapiens 170959   zinc finger protein 431
Homo sapiens ENSG00000221923   zinc finger protein 880
Homo sapiens ENSG00000198551   zinc finger protein 627
Homo sapiens ENSG00000186020   zinc finger protein 529
Homo sapiens ENSG00000196466   zinc finger protein 799
Homo sapiens ENSG00000164631   zinc finger protein 12
Homo sapiens ENSG00000196693   zinc finger protein 33B
Homo sapiens ENSG00000183647   zinc finger protein 530
Homo sapiens ENSG00000197566   zinc finger protein 624
Homo sapiens ENSG00000272602   zinc finger protein 595
Homo sapiens 730051   zinc finger protein 814
Homo sapiens 7652   zinc finger protein 99
Homo sapiens ENSG00000198482   zinc finger protein 808
Homo sapiens ENSG00000229676   zinc finger protein 492
Homo sapiens ENSG00000167232   zinc finger protein 91
Homo sapiens ENSG00000213799   zinc finger protein 845
Homo sapiens ENSG00000250312   zinc finger protein 718
Homo sapiens ENSG00000197124   zinc finger protein 682
Homo sapiens ENSG00000204920   zinc finger protein 155
Homo sapiens ENSG00000196110   zinc finger protein 699
Homo sapiens 100287477   zinc finger protein 420-like
Homo sapiens ENSG00000170100   zinc finger protein 778
Loa Loa (eye worm) LOAG_14927   hypothetical protein
Loa Loa (eye worm) LOAG_14238   oocyte zinc finger protein XlCOF14
Loa Loa (eye worm) LOAG_14882   zinc finger protein
Loa Loa (eye worm) LOAG_15080   gastrula zinc finger protein XlCGF57.1
Loa Loa (eye worm) LOAG_16096   zinc finger protein
Loa Loa (eye worm) LOAG_13413   hypothetical protein
Loa Loa (eye worm) LOAG_16215   zinc finger protein
Loa Loa (eye worm) LOAG_16049   hypothetical protein
Loa Loa (eye worm) LOAG_15504   zinc finger protein
Loa Loa (eye worm) LOAG_13277   zinc finger protein
Loa Loa (eye worm) LOAG_16142   zinc finger protein
Loa Loa (eye worm) LOAG_15596   zinc finger protein
Loa Loa (eye worm) LOAG_15545   zinc finger protein
Loa Loa (eye worm) LOAG_12847   zinc finger protein 239
Loa Loa (eye worm) LOAG_15971   zinc finger protein
Loa Loa (eye worm) LOAG_15838   zinc finger protein
Loa Loa (eye worm) LOAG_16231   hypothetical protein
Loa Loa (eye worm) LOAG_16023   zinc finger protein
Loa Loa (eye worm) LOAG_09997   gastrula zinc finger protein XlCGF7.1
Loa Loa (eye worm) LOAG_10027   zinc finger protein
Loa Loa (eye worm) LOAG_16262   zinc finger protein
Loa Loa (eye worm) LOAG_12725   hypothetical protein
Loa Loa (eye worm) LOAG_15762   zinc finger protein
Loa Loa (eye worm) LOAG_15954   zinc finger protein 254
Loa Loa (eye worm) LOAG_12922   hypothetical protein
Loa Loa (eye worm) LOAG_14944   zinc finger protein
Loa Loa (eye worm) LOAG_13232   oocyte zinc finger protein XlCOF26
Loa Loa (eye worm) LOAG_15191   zinc finger protein
Loa Loa (eye worm) LOAG_15984   gastrula zinc finger protein XlCGF17.1
Loa Loa (eye worm) LOAG_15266   hypothetical protein
Mus musculus 102641996   zinc finger protein 665-like
Mus musculus ENSMUSG00000090659   zinc finger protein 493
Mus musculus ENSMUSG00000063894   zinc finger with KRAB and SCAN domains 8
Mus musculus 102638696   predicted gene, 26919
Mus musculus 70190   RIKEN cDNA 2610036A22 gene
Mus musculus 234358   zinc finger protein 930
Mus musculus 56869   zinc finger protein 109
Mus musculus 668030   predicted gene 14432
Mus musculus ENSMUSG00000049421   zinc finger protein 260
Mus musculus 665738   predicted gene 7762
Mus musculus 102631834   predicted gene, 30070
Mus musculus 102642076   zinc finger protein 709-like
Mus musculus 100862427   zinc finger protein 729-like
Mus musculus 102633207   predicted gene, 31094
Mus musculus 102635315   predicted gene, 32687
Mus musculus 102639567   zinc finger protein 468-like
Mus musculus ENSMUSG00000055341   zinc finger protein 457
Mus musculus 102632138   predicted gene, 30291
Mus musculus ENSMUSG00000056383   expressed sequence AI987944
Mus musculus ENSMUSG00000078878   predicted gene 14305
Mus musculus 319535   zinc finger protein 182
Mus musculus 665001   predicted gene 14391
Mus musculus 102632506   predicted gene 12591
Mus musculus 100043915   predicted gene 4724
Mus musculus 102641407   zinc finger protein 120-like
Mus musculus ENSMUSG00000033669   zinc finger protein 7
Mus musculus ENSMUSG00000058186   predicted gene 13242
Mus musculus 102634030   predicted gene, 31714
Mus musculus 240120   zinc finger protein 119b
Mus musculus 73610   RIKEN cDNA 1700123A16 gene
Mus musculus ENSMUSG00000071267   zinc finger protein 942
Mus musculus 102637056   predicted gene, 33962
Mus musculus ENSMUSG00000057093   RIKEN cDNA C030039L03 gene
Mus musculus ENSMUSG00000068130   zinc finger protein 442
Mus musculus ENSMUSG00000048280   zinc finger protein 738
Mus musculus ENSMUSG00000062931   zinc finger protein 938
Mus musculus ENSMUSG00000044807   zinc finger protein 354C
Mus musculus ENSMUSG00000059423   zinc finger protein 933
Mus musculus 54678   zinc finger protein 108
Mus musculus ENSMUSG00000058331   zinc finger protein 85
Mus musculus ENSMUSG00000074832   RIKEN cDNA 2410141K09 gene
Mus musculus ENSMUSG00000074472   zinc finger protein 872
Mus musculus ENSMUSG00000069727   predicted gene 5595
Mus musculus ENSMUSG00000067931   zinc finger protein 948
Mus musculus 102643255   zinc finger protein 658-like
Mus musculus ENSMUSG00000074519   ethanol induced 1
Mus musculus 102632968   predicted gene, 30910
Mus musculus ENSMUSG00000058402   zinc finger protein 420
Mus musculus ENSMUSG00000022526   zinc finger protein 251
Mus musculus 22710   zinc finger protein 52
Mus musculus 102640922   predicted gene, 36870
Mus musculus ENSMUSG00000065999   predicted gene 13154
Mus musculus 102641062   zinc finger protein 28-like
Mus musculus ENSMUSG00000012640   zinc finger protein 715
Mus musculus ENSMUSG00000059975   zinc finger protein 74
Mus musculus ENSMUSG00000079009   predicted gene 14139
Mus musculus 627914   predicted gene 14430
Mus musculus 102641165   zinc finger protein 486-like
Mus musculus 102632467   predicted gene, 30531
Mus musculus ENSMUSG00000062040   zinc finger protein 27
Mus musculus 239546   zinc finger protein 647
Mus musculus 243906   zinc finger protein 14
Mus musculus ENSMUSG00000023892   zinc finger protein 51
Mus musculus ENSMUSG00000029587   zinc finger protein 12
Mus musculus 102641511   zinc finger protein 888-like
Mus musculus 433801   predicted gene 13212
Mus musculus ENSMUSG00000078862   predicted gene 14326
Mus musculus ENSMUSG00000033972   zinc finger protein 944
Mus musculus 234725   zinc finger protein 612
Mus musculus ENSMUSG00000034538   zinc finger protein 418
Mus musculus ENSMUSG00000021510   RIKEN cDNA A530054K11 gene
Mus musculus 102633782   predicted gene, 31526
Mus musculus ENSMUSG00000074166   expressed sequence AW146154
Mus musculus ENSMUSG00000063488   zinc finger with KRAB and SCAN domains 7
Mus musculus ENSMUSG00000045598   zinc finger protein 553
Mus musculus ENSMUSG00000023882   zinc finger protein 54
Mus musculus ENSMUSG00000057895   zinc finger protein 105
Mus musculus 71131   zinc finger protein 689
Mus musculus 24132   zinc finger protein 53
Mus musculus ENSMUSG00000090641   zinc finger protein 712
Mus musculus ENSMUSG00000067919   reduced expression 2
Mus musculus ENSMUSG00000074731   zinc finger protein 345
Mus musculus ENSMUSG00000078546   RIKEN cDNA 2210404O09 gene
Mus musculus ENSMUSG00000074194   zinc finger protein 791
Mus musculus 170740   zinc finger protein 287
Mus musculus 102635548   zinc finger protein 433-like
Mus musculus 102633363   zinc finger protein 14-like
Mus musculus ENSMUSG00000051034   zinc finger protein 11
Mus musculus 329575   predicted gene 14325
Mus musculus 104349   zinc finger protein 119a
Mus musculus ENSMUSG00000056019   zinc finger protein 709
Mus musculus ENSMUSG00000023284   zinc finger protein 605
Mus musculus 100862460   zinc finger protein 813-like
Mus musculus 100040944   predicted gene 3055
Mus musculus 102641453   zinc finger protein 665-like
Mus musculus 634762   predicted gene 7145
Mus musculus ENSMUSG00000067928   zinc finger protein 760
Mus musculus 101055890   predicted gene, 29738
Mus musculus 69623   zinc finger protein 33B
Mus musculus 102642338   zinc finger protein 433-like
Mus musculus 547097   RIKEN cDNA B020011L13 gene
Mus musculus ENSMUSG00000053347   zinc finger prtoein 943
Mus musculus ENSMUSG00000052675   zinc finger protein 112
Mus musculus 100041979   predicted gene 3604
Mus musculus ENSMUSG00000078877   predicted gene 14295
Mus musculus 100041420   predicted gene 3325
Mus musculus 232966   zinc finger protein 114
Mus musculus 102642956   zinc finger protein 888-like
Mus musculus ENSMUSG00000030469   zinc finger protein 719
Mus musculus ENSMUSG00000096433   predicted gene 4944
Mus musculus 100043772   zinc finger protein 850
Mus musculus ENSMUSG00000052446   zinc finger protein 961
Mus musculus 240064   zinc finger protein 799
Mus musculus 73229   RIKEN cDNA 3110052M02 gene
Mus musculus 102641260   zinc finger protein 761-like
Mus musculus 102639598   zinc finger protein 120-like
Mus musculus ENSMUSG00000044501   zinc finger protein 758
Mus musculus ENSMUSG00000058093   expressed sequence AA987161
Mus musculus ENSMUSG00000045639   zinc finger protein 629
Mus musculus 216177   expressed sequence AU041133
Mus musculus 668039   predicted gene 14434
Mus musculus 22755   zinc finger protein 93
Mus musculus 338354   zinc finger protein 780B
Mus musculus ENSMUSG00000074867   zinc finger protein 80
Mus musculus 102633561   predicted gene, 31357
Mus musculus 100039060   RIKEN cDNA 0610010B08 gene
Mus musculus ENSMUSG00000044296   zinc finger protein 879
Mus musculus ENSMUSG00000087598   zinc finger protein 111
Mus musculus ENSMUSG00000078495   predicted gene 13157
Mus musculus 380850   predicted gene 5141
Mus musculus 100861656   predicted gene, 21110
Mus musculus ENSMUSG00000061544   zinc finger protein 229
Mus musculus 102642328   zinc finger protein 665-like
Mus musculus 102635356   predicted gene 14197
Mus musculus 102638775   zinc finger protein 14-like
Mus musculus ENSMUSG00000057842   zinc finger protein 595
Mus musculus ENSMUSG00000066613   zinc finger protein 932
Mus musculus ENSMUSG00000057396   zinc finger protein 759
Mus musculus ENSMUSG00000055102   zinc finger protein 819
Mus musculus 208111   RIKEN cDNA 9830147E19 gene
Mus musculus 102640170   predicted gene, 36302
Mus musculus ENSMUSG00000063281   zinc finger protein 35
Mus musculus ENSMUSG00000057101   zinc finger protein 180
Mus musculus 101055753   zinc finger protein 709-like
Mus musculus 100862442   zinc finger protein 28-like
Mus musculus 102641754   zinc finger protein 665-like
Mus musculus ENSMUSG00000029729   zinc finger with KRAB and SCAN domains 1
Mus musculus 102641342   zinc finger protein 41-like
Mus musculus ENSMUSG00000071281   zinc finger protein 65
Mus musculus ENSMUSG00000049321   zinc finger protein 2
Mus musculus ensembl-mmu:ENSMUSG00000095990   zinc finger protein 97
Mus musculus 102641381   zinc finger protein 658-like
Mus musculus 102642495   zinc finger protein 658B-like
Mus musculus ENSMUSG00000061898   RB-associated KRAB repressor
Mus musculus 102643195   zinc finger protein 180-like
Mus musculus 233987   zinc finger protein 958
Mus musculus ENSMUSG00000011427   zinc finger protein 790
Mus musculus ENSMUSG00000066000   RIKEN cDNA 2610305D13 gene
Mus musculus 623688   predicted gene 6445
Mus musculus ENSMUSG00000048012   zinc finger protein 473
Mus musculus 102636566   zinc finger protein 564-like
Mus musculus 102632416   zinc finger protein 700-like
Mus musculus ENSMUSG00000003198   zinc finger protein 959
Mus musculus ENSMUSG00000066009   predicted gene 13051
Mus musculus 628308   predicted gene 14420
Mus musculus ENSMUSG00000062743   zinc finger protein 677
Mus musculus ENSMUSG00000038630   zinc finger with KRAB and SCAN domains 16
Mus musculus 102635208   zinc finger protein 709-like
Mus musculus ENSMUSG00000097333   zinc finger protein 87
Mus musculus ENSMUSG00000052751   replication initiator 1
Mus musculus ENSMUSG00000002617   zinc finger protein 40
Mus musculus ENSMUSG00000072774   zinc finger protein 951
Mus musculus 102642386   zinc finger protein 120-like
Mus musculus 101055933   predicted gene, 29746
Mus musculus 102638745   zinc finger protein 709-like
Mus musculus ensembl-mmu:ENSMUSG00000098022   zinc finger protein 82
Mus musculus ENSMUSG00000066880   zinc finger protein 617
Mus musculus ENSMUSG00000055480   zinc finger protein 458
Mus musculus ENSMUSG00000030446   zinc finger protein 273
Mus musculus 102643186   zinc finger protein 888-like
Mus musculus 545938   zinc finger proten 607
Mus musculus 668620   zinc finger protein 936
Mus musculus ENSMUSG00000067916   predicted gene 13139
Mus musculus ENSMUSG00000030443   zinc finger protein 583
Mus musculus 102636383   zinc finger protein 658-like
Mus musculus 408062   zinc finger protein 873
Mus musculus ENSMUSG00000039634   zinc finger protein 189
Mus musculus ENSMUSG00000068959   zinc finger protein 619
Mus musculus ENSMUSG00000069743   zinc finger protein 820
Mus musculus ENSMUSG00000059142   zinc finger protein 945
Mus musculus ENSMUSG00000050846   zinc finger protein 623
Mus musculus 100043381   predicted gene 14308
Mus musculus 102639700   zinc finger protein 120-like
Mus musculus 245174   zinc finger protein 937
Mus musculus 102640477   predicted gene 14412
Mus musculus ENSMUSG00000095909   predicted gene 10324
Mus musculus ENSMUSG00000006720   zinc finger protein 184 (Kruppel-like)
Mus musculus ENSMUSG00000031907   zinc finger protein 90
Mus musculus 100170401   expressed sequence EU599041
Mus musculus ENSMUSG00000046311   zinc finger protein 62
Mus musculus ENSMUSG00000079008   predicted gene 14124
Mus musculus 102632383   zinc finger protein 2 homolog
Mus musculus 102639229   predicted gene, 35588
Mus musculus ensembl-mmu:ENSMUSG00000037001   zinc finger protein 39
Mus musculus ENSMUSG00000062861   zinc finger protein 28
Mus musculus 101055987   predicted gene, 29758
Mus musculus ENSMUSG00000070605   predicted gene 13251
Mus musculus ENSMUSG00000066007   zinc finger protein 600
Mus musculus 102642744   zinc finger protein 709-like
Mus musculus 22718   zinc finger protein 60
Mus musculus 629967   predicted gene 11677
Mus musculus 77117   zinc finger protein 934
Mus musculus 100503584   zinc finger protein 534
Mus musculus ENSMUSG00000033883   DNA segment, Chr 3, ERATO Doi 254, expressed
Mus musculus 22717   zinc finger protein 59
Mus musculus 330463   zinc finger protein 78
Mus musculus 102641241   zinc finger protein 709-like
Mus musculus ENSMUSG00000063383   zinc finger protein 947
Mus musculus ENSMUSG00000069184   zinc finger protein 72
Mus musculus 102636264   predicted gene, 33378
Mus musculus 102637083   predicted gene, 33985
Mus musculus ENSMUSG00000045519   zinc finger protein 560
Mus musculus 626802   predicted gene 14322
Mus musculus ENSMUSG00000074220   zinc finger protein 382
Mus musculus ENSMUSG00000030386   zinc finger protein 606
Mus musculus 100044193   predicted gene, 20939
Mus musculus ENSMUSG00000096856   predicted gene 10778
Mus musculus ensembl-mmu:ENSMUSG00000032425   zinc finger protein 949
Mus musculus ENSMUSG00000056592   zinc finger protein 658
Mus musculus ENSMUSG00000099689   zinc finger protein 383
Mus musculus 56525   zinc finger protein 235
Mus musculus 228876   zinc finger protein 334
Mus musculus ENSMUSG00000071266   zinc finger protein 946
Mus musculus ENSMUSG00000074165   zinc finger protein 788
Mus musculus ENSMUSG00000067942   zinc finger protein 160
Mus musculus ENSMUSG00000095432   zinc finger protein 748
Mus musculus 102642438   zinc finger protein 677-like
Mus musculus ENSMUSG00000070709   RIKEN cDNA 1700049G17 gene
Mus musculus ENSMUSG00000063108   zinc finger protein 26
Mus musculus 102642606   zinc finger protein 120-like
Mus musculus 626832   predicted gene 6710
Mus musculus 22693   zinc finger protein 30
Mus musculus ENSMUSG00000056300   predicted gene 13247
Mus musculus 732521   gene trap 140, Institute of Molecular Embryology and Genetics
Mus musculus 100502880   predicted gene, 19428
Mus musculus ENSMUSG00000034071   zinc fingr protein 551
Mus musculus ENSMUSG00000096696   zinc finger protein 960
Mus musculus 102634489   predicted gene, 32060
Mus musculus ENSMUSG00000100235   zinc finger protein 708
Mus musculus 102638847   predicted gene, 35315
Oryza sativa 4331626   Os03g0148800
Onchocerca volvulus OVOC11471   Zinc finger protein 781 homolog
Onchocerca volvulus OVOC12815  
Onchocerca volvulus OVOC8039  
Onchocerca volvulus OVOC8026  
Onchocerca volvulus OVOC12932  
Onchocerca volvulus OVOC7944  
Onchocerca volvulus OVOC12297  
Onchocerca volvulus OVOC3186  
Onchocerca volvulus OVOC12663  
Onchocerca volvulus OVOC9071  
Onchocerca volvulus OVOC9178  
Onchocerca volvulus OVOC12980  
Onchocerca volvulus OVOC12469  
Onchocerca volvulus OVOC7854  
Plasmodium berghei PBANKA_0607700   zinc finger transcription factor, putative
Plasmodium falciparum PF3D7_1209300   zinc finger transcription factor, putative
Plasmodium knowlesi PKNH_1309200   zinc finger transcription factor, putative
Plasmodium vivax PVX_084495   zinc finger transcription factor, putative
Schistosoma japonicum Sjp_0108280   Early growth response protein 4, putative
Schistosoma japonicum Sjp_0054510   Zinc finger protein 91, putative
Schistosoma japonicum Sjp_0063630   ko:K09228 KRAB domain-containing zinc finger protein, putative
Schistosoma mansoni Smp_160440   zinc finger protein
Schistosoma mansoni Smp_160730   zinc finger protein
Schmidtea mediterranea mk4.008759.00  
Schmidtea mediterranea mk4.011001.00  
Schmidtea mediterranea mk4.008258.00  
Schmidtea mediterranea mk4.006751.00  
Schmidtea mediterranea mk4.011269.03   Putative zinc finger protein
Schmidtea mediterranea mk4.000873.03  
Schmidtea mediterranea mk4.014546.00  
Schmidtea mediterranea mk4.000000.52   Putative zinc finger protein
Schmidtea mediterranea mk4.017375.01  
Schmidtea mediterranea mk4.007222.01  
Schmidtea mediterranea mk4.002524.02   Zinc finger protein 781
Schmidtea mediterranea mk4.004002.01  
Theileria parva TP03_0733   hypothetical protein

Essentiality

Bm1_00290 has one or more orthologs with essentiality data
Gene/Ortholog Organism Phenotype Source Study
PBANKA_0607700 Plasmodium berghei Essential plasmo
Show/Hide essentiality data references
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.


Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Non orthologous druggable targets
By sequence similarity to non orthologous druggable targets
No additional associated druggable targets

Obtained from network model
No druggable targets predicted through repurposing network model

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

No literature references available for this target.

If you have references for this gene, please enter them in a user comment (below) or Contact us.

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Gene identifier Bm1_00290 (Brugia malayi), Zinc finger, C2H2 type family protein
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