Detailed view for TGME49_294820

Basic information

TDR Targets ID: 262468
Toxoplasma gondii, type I fatty acid synthase, putative

Source Database / ID:  ToxoDB 

pI: 6.3275 | Length (AA): 10021 | MW (Da): 1093469 | Paralog Number: 4

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG5

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Pfam domains

PF00107   Zinc-binding dehydrogenase
PF00109   Beta-ketoacyl synthase, N-terminal domain
PF00501   AMP-binding enzyme
PF00550   Phosphopantetheine attachment site
PF00698   Acyl transferase domain
PF02801   Beta-ketoacyl synthase, C-terminal domain
PF07993   Male sterility protein
PF08240   Alcohol dehydrogenase GroES-like domain
PF08659   KR domain
PF13469   Sulfotransferase family
PF14765   Polyketide synthase dehydratase
PF16197   Ketoacyl-synthetase C-terminal extension

Gene Ontology

Mouse over links to read term descriptions.
GO:0031177   phosphopantetheine binding  
GO:0016491   oxidoreductase activity  
GO:0008270   zinc ion binding  
GO:0005488   binding  
GO:0004043   L-aminoadipate-semialdehyde dehydrogenase activity  
GO:0003824   catalytic activity  
GO:0000036   acyl carrier activity  
GO:0048037   cofactor binding  
GO:0016740   transferase activity  
GO:0008152   metabolic process  
GO:0055114   oxidation reduction  

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

There are 43 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg Target End Template Template Beg Template End Identity Evalue Model Score MPQS zDope
1 930 4zxh (A) 433 1094 18.00 0 1 -0.269195 1.55
45 960 5ja1 (A) 453 1278 17.00 0 1 0.035408 0.79
61 241 4wd1 (A) 105 290 23.00 0.52 1 0.326362 -0.71
471 597 3ipl (A) 328 429 39.00 0.3 0.32 0.0169734 1.35
908 1334 4qyr (A) 2544 2973 46.00 0 1 0.611911 -0.72
912 1349 4opf (A) 6124 6542 42.00 0 1 0.313008 -0.02
912 1338 4tkt (A) 3144 3577 41.00 0 1 0.573911 -0.74
1283 1696 4qbu (A) 33 433 27.00 0 1 0.326313 -0.22
1352 1662 3im9 (A) 0 299 22.00 0 1 0.341035 -0.87
2244 2916 3slk (A) 69 716 38.00 0 1 0.382459 0.42
2396 2659 4dvj (A) 50 323 29.00 0.00000000049 1 0.379645 -0.36
2532 2962 2fr0 (A) 1477 1915 27.00 0 1 0.23401 0.32
2971 3059 5hv8 (A) 2050 2140 37.00 0.00000064 1 0.519881 -1.08
2977 3056 2mf4 (A) 0 6811 30.00 0.0002 1 0.479983 -1.29
3078 3867 4mz0 (A) 38 920 44.00 0 1 0.517134 -0.61
3079 5091 2vz9 (A) 2 2090 29.00 0 1 0.320178 0.68
3520 3828 3im8 (A) 3 301 31.00 0 1 0.471635 -1.24
3520 3836 3h0p (A) 3 307 32.00 0 1 0.413934 -0.85
4809 5129 4imp (A) 211 515 35.00 0 1 0.332333 0.27
4839 5705 2uv8 (A) 642 1689 18.00 0 1 -0.000681688 0.95
5138 5224 2ju1 (A) 2 94 38.00 0.000015 1 0.483982 -0.78
5147 5225 4neo (A) 8 85 23.00 0 0.86 0.458683 -1.93
5153 5222 3gzm (A) 6 77 21.00 0 0.98 0.412785 -1.59
5702 6016 5tz6 (A) 943 1239 21.00 0 1 0.189434 -0.35
6073 6871 3slk (A) 9 749 33.00 0 1 0.309733 0.53
6279 6606 5dp1 (A) 5 334 43.00 0 1 0.541731 -0.86
6302 6370 5tnx (A) 27 100 45.00 0.37 0.67 0.403186 0.28
6393 6571 4oki (A) 671 849 36.00 0 1 0.516863 -1.06
6611 7656 3hmj (A) 663 1873 16.00 0 1 -0.0548192 1.47
6614 6883 4hxy (A) 172 435 37.00 0 1 0.393243 -0.19
6895 6975 1x3o (A) 1 79 28.00 0.76 0.96 0.490083 -1.73
6925 6975 4hkg (A) 30 80 33.00 0.13 0.87 0.533389 -1.34
6972 7794 4mz0 (A) 3 934 41.00 0 1 0.423128 -0.28
7000 8961 2vz8 (A) 2 2105 24.00 0 1 0.247789 0.71
7454 7760 3h0p (A) 3 298 27.00 0 1 0.361636 -0.68
8470 8650 4oki (A) 670 849 33.00 0 1 0.484862 -0.97
8732 9025 5ldg (A) 6 300 17.00 0 1 0.135138 0.43
8733 9003 1jtv (A) 4 278 18.00 0.000000089 0.89 0.167043 0.42
9007 9080 3gzm (A) 4 78 22.00 0.43 0.81 0.415385 -1.64
9171 9525 3oh8 (A) 89 404 19.00 0.55 0.96 -0.0655744 0.8
9212 9613 4w4t (A) 1125 1513 31.00 0 1 0.398116 -0.65
9617 10006 2zq5 (A) 10 382 29.00 0 1 0.367918 -0.66
9617 10010 2z6v (A) 7 384 25.00 0 1 0.356117 -0.58

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

Upregulation Percent Ranking Stage Dataset
Mid 40-60% percentile VEG Tachyzoite, ME49 Tachyzoite. Gregory
Upregulation Percent Ranking Stage Dataset
Lower 20-40% percentile ME49 merozoite, ME49 Oocyst. Hehl AB Fritz HM
Upregulation Percent Ranking Stage Dataset
Lower 0-20% percentile ME49 Bradyzoite. Sibley/Greg
Show/Hide expression data references
  • Fritz HM Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts.
  • Sibley/Greg ToxoDB
  • Gregory ToxoDB
  • Hehl AB Asexual expansion of Toxoplasma gondii merozoites is distinct from tachyzoites and entails expression of non-overlapping gene families to attach, invade, and replicate within feline enterocytes.

Orthologs

Ortholog group members (OG5_126633)

Species Accession Gene Product
Brugia malayi Bm1_08575   Beta-ketoacyl synthase, N-terminal domain containing protein
Brugia malayi Bm1_35180   oxidoreductase, zinc-binding dehydrogenase family protein
Caenorhabditis elegans CELE_F32H2.5   Protein FASN-1
Cryptosporidium hominis Chro.30258   hypothetical protein
Cryptosporidium hominis Chro.40330   hypothetical protein
Cryptosporidium parvum cgd4_2900   polyketide synthase
Cryptosporidium parvum cgd3_2180   type I fatty acid synthase
Dictyostelium discoideum DDB_G0281475   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0284001   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0271000   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0271614   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0291684   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290703   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0271530   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0288457   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0275077   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0291614   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0271618   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0271524   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290709   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0293912   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290729   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0295667   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0272981   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0275069   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0283931   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290943   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0271662   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290853   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290701   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290469   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0269364   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0270572   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0287095   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0291604   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0273007   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290937   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0282029   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0272859   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0282027   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0287119   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0292544   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0295659   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0293902   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290467   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290699   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0271520   beta-ketoacyl synthase family protein
Dictyostelium discoideum DDB_G0290737   beta-ketoacyl synthase family protein
Drosophila melanogaster Dmel_CG3523   CG3523 gene product from transcript CG3523-RA
Drosophila melanogaster Dmel_CG17374   CG17374 gene product from transcript CG17374-RC
Drosophila melanogaster Dmel_CG3524   CG3524 gene product from transcript CG3524-RB
Homo sapiens ENSG00000169710   fatty acid synthase
Loa Loa (eye worm) LOAG_12875   acyl carrier protein
Loa Loa (eye worm) LOAG_12856   hypothetical protein
Loa Loa (eye worm) LOAG_05412   fatty acid synthase
Loa Loa (eye worm) LOAG_06344   hypothetical protein
Loa Loa (eye worm) LOAG_05695   hypothetical protein
Mycobacterium leprae ML2353c   PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE
Mycobacterium leprae ML2356c   PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB
Mycobacterium leprae ML1229   PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS4
Mycobacterium leprae ML2357c   PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA
Mycobacterium leprae ML2354c   PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD
Mycobacterium leprae ML0101   Polyketide synthase Pks13
Mycobacterium leprae ML0139   Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas
Mycobacterium leprae ML2355c   PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC
Mycobacterium leprae ML0135   Probable polyketide synthase Pks1
Mus musculus ENSMUSG00000025153   fatty acid synthase
Mycobacterium tuberculosis Rv2931   Phenolpthiocerol synthesis type-I polyketide synthase PpsA
Mycobacterium tuberculosis Rv2933   Phenolpthiocerol synthesis type-I polyketide synthase PpsC
Mycobacterium tuberculosis Rv2934   Phenolpthiocerol synthesis type-I polyketide synthase PpsD
Mycobacterium tuberculosis Rv2940c   Probable multifunctional mycocerosic acid synthase membrane-associated Mas
Mycobacterium tuberculosis Rv1527c   Probable polyketide synthase Pks5
Mycobacterium tuberculosis Rv1180   Probable polyketide beta-ketoacyl synthase Pks3
Mycobacterium tuberculosis Rv1181   Probable polyketide beta-ketoacyl synthase Pks4
Mycobacterium tuberculosis Rv2048c   Polyketide synthase Pks12
Mycobacterium tuberculosis Rv3800c   Polyketide synthase Pks13
Mycobacterium tuberculosis Rv0405   Probable membrane bound polyketide synthase Pks6
Mycobacterium tuberculosis Rv1661   Probable polyketide synthase Pks7
Mycobacterium tuberculosis Rv1662   Probable polyketide synthase Pks8
Mycobacterium tuberculosis Rv2935   Phenolpthiocerol synthesis type-I polyketide synthase PpsE
Mycobacterium tuberculosis Rv2932   Phenolpthiocerol synthesis type-I polyketide synthase PpsB
Mycobacterium tuberculosis Rv1664   Probable polyketide synthase Pks9
Mycobacterium tuberculosis Rv2947c   Probable polyketide synthase Pks15
Mycobacterium tuberculosis Rv2946c   Probable polyketide synthase Pks1
Mycobacterium tuberculosis Rv3825c   Polyketide synthase Pks2
Mycobacterium ulcerans MUP039c   Type I modular polyketide synthase
Mycobacterium ulcerans MUL_2018   phenolpthiocerol synthesis type-I polyketide synthase PpsB
Mycobacterium ulcerans MUP040c   Type I modular polyketide synthase
Mycobacterium ulcerans MUL_2005   polyketide synthase
Mycobacterium ulcerans MUL_1655   polyketide synthase Pks9
Mycobacterium ulcerans MUL_2016   phenolpthiocerol synthesis type-I polyketide synthase PpsD
Mycobacterium ulcerans MUL_2010   multifunctional mycocerosic acid synthase membrane-associated Mas
Mycobacterium ulcerans MUL_2015   phenolpthiocerol synthesis type-I polyketide synthase PpsE
Mycobacterium ulcerans MUP032c   Type I modular polyketide synthase
Mycobacterium ulcerans MUL_2266   polyketide synthase
Mycobacterium ulcerans MUL_2019   phenolpthiocerol synthesis type-I polyketide synthase PpsA
Mycobacterium ulcerans MUL_4983   polyketide synthase Pks13
Mycobacterium ulcerans MUL_2017   phenolpthiocerol synthesis type-I polyketide synthase PpsC
Neospora caninum NCLIV_001690   Short-chain dehydrogenase/reductase SDR, related
Neospora caninum NCLIV_020690   Soraphen polyketide synthase A, related
Neospora caninum NCLIV_050890   KR domain domain-containing protein, putative
Onchocerca volvulus OVOC1839  
Onchocerca volvulus OVOC5784   Fatty acid synthase homolog
Schmidtea mediterranea mk4.052433.01  
Toxoplasma gondii TGME49_294820   type I fatty acid synthase, putative
Toxoplasma gondii TGME49_204560   type I fatty acid synthase, putative
Toxoplasma gondii TGME49_326200   type I fatty acid synthase
Toxoplasma gondii TGME49_236990   beta-ketoacyl synthase, N-terminal domain-containing protein
Toxoplasma gondii TGME49_236980   AMP-binding enzyme domain-containing protein

Essentiality

TGME49_294820 has direct evidence of essentiality
Gene/Ortholog Organism Phenotype Source Study
mtu2988 Mycobacterium tuberculosis non-essential nmpdr
mtu3867 Mycobacterium tuberculosis essential nmpdr
mtu408 Mycobacterium tuberculosis non-essential nmpdr
mtu1690 Mycobacterium tuberculosis essential nmpdr
mtu1691 Mycobacterium tuberculosis essential nmpdr
mtu2981 Mycobacterium tuberculosis non-essential nmpdr
CELE_F32H2.5 Caenorhabditis elegans embryonic arrest wormbase
CELE_F32H2.5 Caenorhabditis elegans embryonic lethal wormbase
CELE_F32H2.5 Caenorhabditis elegans larval arrest wormbase
CELE_F32H2.5 Caenorhabditis elegans sterile wormbase
TGME49_294820 this record Toxoplasma gondii Essentiality uncertain sidik
TGME49_204560 Toxoplasma gondii Essentiality uncertain sidik
TGME49_236990 Toxoplasma gondii Essentiality uncertain sidik
TGME49_236980 Toxoplasma gondii Essentiality uncertain sidik
TGME49_326200 Toxoplasma gondii Essentiality uncertain sidik
TGME49_294820 this record Toxoplasma gondii Probably non-essential sidik
TGME49_204560 Toxoplasma gondii Probably non-essential sidik
TGME49_236990 Toxoplasma gondii Probably non-essential sidik
TGME49_236980 Toxoplasma gondii Probably non-essential sidik
TGME49_326200 Toxoplasma gondii Probably non-essential sidik
Show/Hide essentiality data references
  • yeastgenome Systematic deletion of yeast genes Saccharomyces Genome Database
  • wormbase C. elegans RNAi experiments WormBase web site, http://www.wormbase.org, release WS170
  • goodall The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis) Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.
  • plasmo Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes. Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.
  • blattner Systematic mutagenesis of the E. coli (MG1655) genome J Bacteriol 2004, 186:4921-4930
  • shigen Profiling of E. coli Chromosome (PEC) National Institute of Genetics, Japan
  • nmpdr Genome-scale essentiality datasets from published studies (M. tuberculosis) National Microbial Pathogen Data Resource
  • neb C. elegans RNAi phenotypes Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs
  • keio Systematic single-gene knock-out mutants of E. coli K12 The Keio Collection
  • alsford High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome Genome Res 2011, 21:915-924
  • sidik A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes. Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.
  • gerdes Experimental determination and system-level analysis of essential genes in E. coli MG1655 Gerdes et al., J Bacteriol. 2003 185:5673-84

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.


Annotated validation

No validation data for this target

Associated compounds / Druggability

Druggability index (range: 0 to 1): 0.5


Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets
Species Known druggable target Linked compounds Reference
Rattus norvegicus Fatty acid synthase Compounds References
Gallus gallus Fatty acid synthase Compounds References
Mus musculus fatty acid synthase Compounds References
Homo sapiens fatty acid synthase Compounds References
By sequence similarity to non orthologous druggable targets
Species Target Length Identity Alignment span Linked Drugs Reference
Staphylococcus aureus 3-oxoacyl-[acyl-carrier-protein] synthase 2 403 aa 23.6% 415 aa Compounds References
Photuris pennsylvanica Luciferase 552 aa 20.9% 613 aa Compounds References
Photuris pennsylvanica Luciferin 4-monooxygenase 545 aa 21.0% 523 aa Compounds References
Photinus pyralis Luciferin 4-monooxygenase 550 aa 19.8% 514 aa Compounds References
Luciola lateralis Luciferase 548 aa 22.2% 510 aa Compounds References

Obtained from network model

Ranking Plot


Putative Drugs List


Compound Raw Global Species
0.0618 0.4773 1
0.1118 0.4773 1
0.0032 0.473 1
0.1264 0.4773 1
0.0026 0.3476 1
0.0961 0.4682 1
0.0252 0.3998 1
0.0032 0.4752 1
0.0032 0.4752 1
0.0179 0.4479 0.3744
0.0745 0.5423 1
0.0032 0.4752 1
0.0036 0.4752 1
0.0029 0.443 1
0.0961 0.4984 1
0.0086 0.2709 1
0.0032 0.4752 1
0.1111 0.4934 1
0.0486 0.4773 1
0.0028 0.2646 0.2112
0.0032 0.4752 1
0.0532 0.4752 0.4276
0.0732 0.557 1
0.0691 0.2757 1
0.0255 0.4521 1
0.0164 0.4933 1
0.057 0.3978 0.9151
0.0701 0.2535 1
0.1582 0.5503 1
0.0032 0.4752 1
0.0057 0.463 0.4376
0.0064 0.4587 1
0.0032 0.4752 1
0.0685 0.4844 1
0.0697 0.5409 1
0.0134 0.4752 1
0.0032 0.4721 1
0.0557 0.4752 1
0.0163 0.4752 1
0.0538 0.4736 1
0.0456 0.4015 1
0.0032 0.2752 1
0.0304 0.4672 1
0.0897 0.4741 1
0.0907 0.4648 1
0.0578 0.4872 1
0.4729 0.559 1
0.0032 0.4331 1
0.0032 0.4752 1
0.0032 0.4752 1
0.0695 0.2721 1
0.0159 0.4694 1
0.0032 0.4752 1
0.0878 0.5411 1
0.0079 0.4752 1
0.0695 0.4203 1
0.0468 0.5244 1
0.0032 0.3611 0.3046
0.0612 0.3229 1
0.0721 0.5568 1
0.0032 0.4752 1
0.0033 0.3841 1
0.0079 0.2833 0.3552
0.0666 0.554 1
0.2282 0.3909 1
0.0997 0.4653 1
0.0032 0.443 1
0.0824 0.4773 1
0.0032 0.4749 1
0.0032 0.4752 1
0.0017 0.473 1
0.0193 0.5274 1
0.0032 0.4752 1
0.0211 0.4752 1
0.0142 0.4773 1
0.0032 0.4752 1
0.0083 0.4773 1
0.0679 0.5233 1
0.0032 0.443 1
0.1153 0.4773 1
0.0948 0.5447 1
0.1236 0.473 1
0.0948 0.5447 1
0.0031 0.4411 1
0.1167 0.4752 1
0.0028 0.473 1
0.022 0.4542 0.4269
0.0107 0.4752 1
0.0732 0.5576 1
0.021 0.5122 1
0.0999 0.5569 1
0.0079 0.332 0.3959
0.0026 0.4773 1
0.0087 0.445 1
0.0699 0.2785 1
0.0295 0.472 1
0.1135 0.5237 1
0.1514 0.5217 1
0.0032 0.4752 1
0.0721 0.5568 1
0.1167 0.4752 1
0.0599 0.5555 1
0.1053 0.4953 1
0.0032 0.4752 1
0.0036 0.4449 0.9029
0.0058 0.473 1
0.0031 0.4773 1
0.0714 0.4752 1
0.0856 0.4741 1
0.0164 0.4953 1
0.0054 0.473 1
0.0697 0.5409 1
0.0944 0.4773 1
0.0092 0.463 1
0.0032 0.4752 1
0.0031 0.4773 1
0.0405 0.4773 1
0.0438 0.5556 1
0.0032 0.4752 1
0.0666 0.554 1
0.0107 0.445 1
0.0249 0.3026 1
0.0602 0.4933 1
0.4372 0.5581 1
0.0768 0.4653 1
0.4438 0.5588 0.6132
0.0457 0.4773 1
0.0026 0.463 0.9359
0.0032 0.4752 1
0.0032 0.4331 1
0.4372 0.5581 1
0.0064 0.4608 1
0.1463 0.4953 1
0.1354 0.5457 1
0.0033 0.4633 0.7736
0.029 0.4503 0.9591
0.0709 0.4333 1
0.1049 0.473 1
0.0672 0.4882 1
0.017 0.463 1
0.0108 0.4752 1
0.0032 0.2691 1
0.0348 0.4752 1
0.0032 0.3264 1
0.0992 0.4773 1
0.0248 0.4518 1
0.0373 0.4773 1
0.0032 0.4752 1
0.1469 0.5356 1
0.0145 0.473 1
0.0664 0.2646 1
0.022 0.551 1
0.0271 0.3175 1
0.0032 0.4752 1
0.0119 0.2827 0.2676
0.1017 0.4752 1
0.0966 0.3416 1
0.0138 0.4752 1
0.0032 0.473 1
0.13 0.4953 1
0.0723 0.2872 1
0.0697 0.4279 1
0.0335 0.4901 1
0.0079 0.473 1
0.0032 0.4411 1
0.1402 0.5581 1
0.0081 0.4752 1
0.0966 0.3416 1
0.0324 0.4773 1
0.0659 0.4752 1
0.0028 0.4773 1
0.0071 0.2948 0
0.0032 0.4752 1
0.0032 0.473 1
0.0032 0.3354 1
0.036 0.4773 1
0.0593 0.4715 1
0.035 0.4727 1
0.0028 0.2646 0.2112
0.0032 0.4752 1
0.0032 0.4752 1
0.0064 0.4608 1
0.0056 0.4752 1
0.0032 0.473 1
0.0032 0.443 1
0.013 0.5244 1
0.0108 0.4752 1
0.0032 0.4773 1
0.0854 0.5446 1
0.0032 0.473 1
0.0658 0.5572 1
0.0147 0.473 1
0.0083 0.4752 1
0.0196 0.4933 1
0.1052 0.4752 1
0.0032 0.4116 1
0.0064 0.4587 1
0.0032 0.473 0.5068
0.0032 0.443 1
0.0032 0.4752 1
0.1156 0.5508 1
0.057 0.3978 0.9151
0.0032 0.4752 1
0.0032 0.2666 1
0.0064 0.4608 1
0.0026 0.4773 1
0.0517 0.5556 1
0.0342 0.473 1
0.1233 0.5416 1
0.1117 0.4885 1
0.1057 0.3309 0.9059
0.0163 0.4848 1
0.0891 0.4645 1
0.0172 0.4773 1
0.0032 0.4752 1
0.3678 0.5587 1
0.0032 0.4752 1
0.0032 0.4752 1
0.0032 0.473 1
0.0027 0.373 0.305
0.0788 0.5556 1
0.0032 0.4752 1
0.0345 0.4807 1
0.0374 0.4752 1
0.0845 0.4773 1
0.0032 0.4752 1
0.0907 0.4648 1
0.0249 0.3026 1
0.0032 0.4752 1
0.1421 0.5509 1
0.0165 0.4503 1
0.0032 0.3354 1
0.0139 0.4351 1
0.1463 0.4953 1
0.0032 0.4752 1
0.1009 0.4773 1
0.0032 0.473 1
0.0027 0.2646 0.2112
0.0027 0.3264 0.3074
0.057 0.3978 0.9151
0.1236 0.473 1
0.0691 0.4323 1
0.1022 0.5353 1
0.003 0.2561 1
0.0745 0.5423 1
0.0064 0.4608 1
0.0059 0.4752 1
0.0245 0.4773 1
0.003 0.463 1
0.0321 0.3869 1
0.0032 0.4752 1
0.0304 0.5271 1
0.0058 0.4608 1
0.0534 0.4714 1
0.1167 0.4752 1
0.0593 0.4715 1
0.1142 0.4848 1
0.0467 0.4734 1
0.0701 0.2506 1
0.0064 0.4608 1
0.057 0.3978 0.9151
0.008 0.4752 1
0.0304 0.509 1
0.0032 0.443 1
0.0536 0.4652 1
0.0249 0.3026 1
0.4372 0.5581 1
0.1421 0.5509 1
0.0032 0.4752 1
0.0032 0.4752 1
0.0032 0.473 0.734
0.0032 0.4752 1
0.0705 0.4773 1
0.0672 0.4943 1
0.0361 0.5262 0.634
0.0032 0.3373 0.2879
0.0032 0.4752 1
0.0605 0.4648 1
0.0032 0.271 1
0.0032 0.4752 1
0.1143 0.338 1
0.0032 0.4752 1
0.0032 0.473 1
0.0032 0.4317 0.3612
0.0405 0.5331 1
0.0234 0.4752 1
0.0748 0.4174 0.3763
0.0055 0.2579 1
0.0032 0.463 1
0.0032 0.4752 1
0.0378 0.4752 0.9902
0.0032 0.4752 1
0.0032 0.3073 1
0.0081 0.473 1
0.0237 0.4411 1
0.05 0.4581 1
0.0032 0.443 1
0.0047 0.2667 0
0.01 0.3212 0.2993
0.0032 0.4752 1
0.0948 0.5447 1
0.0047 0.3724 1
0.0762 0.5348 1
0.0032 0.4752 1
0.0032 0.443 1
0.1398 0.4953 1
0.0032 0.4752 1
0.1167 0.4752 1
0.0165 0.2868 1
0.0842 0.2936 1
0.1167 0.4752 1
0.008 0.4752 1
0.1479 0.548 1
0.0169 0.4752 1
0.073 0.474 1
0.1513 0.5463 1
0.0588 0.3826 1
0.0666 0.554 1
0.0052 0.473 1
0.014 0.4798 1
0.0329 0.4773 1
0.0057 0.3387 1
0.0032 0.473 1
0.0622 0.4738 1
0.0064 0.4608 1
0.1085 0.4773 1
0.4438 0.5379 1
0.0032 0.4752 1
0.1085 0.4773 1
0.0032 0.4752 1
0.1476 0.5255 1
0.1195 0.512 1
0.0855 0.4752 1
0.0032 0.4752 1
0.0992 0.4773 1
0.008 0.4752 1
0.0032 0.473 1
0.0026 0.463 1
0.0032 0.4752 1
0.0032 0.4752 1
0.0639 0.4773 1
0.0677 0.4645 1
0.057 0.3978 0.9151
0.0415 0.4752 1
0.4154 0.5581 0.6077
0.076 0.5481 1
0.0611 0.4752 1
0.0032 0.4359 0.3612
0.0107 0.4665 1
0.0032 0.4752 1
0.0592 0.5462 1
0.0199 0.4411 1
0.0345 0.3531 1
0.1028 0.4933 1
0.0032 0.4752 1
0.0239 0.4782 1
0.1142 0.4848 1
0.1009 0.4752 1
0.1259 0.5538 1
0.0738 0.4476 1
0.0092 0.4339 1
0.0032 0.473 1
0.0053 0.4752 1
0.0221 0.2965 1
0.0148 0.3702 0.3621
0.0032 0.4411 1
0.0099 0.3233 0.0064
0.0058 0.463 1
0.0379 0.4752 1
0.0659 0.4752 1
0.0695 0.4203 1
0.1156 0.5508 1
0.048 0.4773 1
0.0032 0.4752 1
0.0032 0.473 1
0.0032 0.4752 1
0.0796 0.4648 1
0.0114 0.4773 1
0.0026 0.463 0.9359
0.0451 0.4773 1
0.0199 0.4411 1
0.0032 0.4752 1
0.0721 0.5568 1
0.0745 0.5423 1
0.0267 0.4773 1
0.0032 0.4752 1
0.0535 0.5394 1
0.0054 0.4608 1
0.0468 0.4752 1
0.057 0.3978 0.9151
0.0032 0.4697 1
0.0666 0.554 1
0.0115 0.3243 0.1689
0.0818 0.5356 1
0.0896 0.4741 1
0.0295 0.4752 1
0.1057 0.3309 0.9059
0.2278 0.5572 1
0.0032 0.4116 1
0.0092 0.463 1
0.0108 0.4752 1
0.4372 0.5581 1
0.0032 0.4721 1
0.0064 0.2562 1
0.0051 0.251 0.0623
0.0515 0.5407 1
0.0748 0.4174 0.3763
0.0666 0.554 1
0.0032 0.4262 1
0.0079 0.4773 1
0.0704 0.4773 1
0.0715 0.4773 1
0.057 0.3978 0.9151
0.0078 0.3176 0.7439
0.0178 0.473 1
0.0054 0.473 1
0.0108 0.4752 1
0.1142 0.4848 1
0.0078 0.3176 0.7439
0.0032 0.4752 1
0.0666 0.554 1
0.0141 0.463 0.985
0.1421 0.5509 1
0.0831 0.464 1
0.1582 0.5503 1
0.0705 0.4649 1
0.058 0.5541 1
0.034 0.4726 1
0.1079 0.4773 1
0.0054 0.473 1
0.0032 0.4752 1
0.0176 0.5244 1
0.0032 0.4024 1
0.0032 0.443 1
0.0825 0.5576 1
0.0032 0.4752 1
0.0142 0.4933 1
0.0438 0.5556 1
0.0666 0.554 1
0.0664 0.4755 1
0.006 0.4752 1
0.0139 0.4752 1
0.0666 0.554 1
0.0173 0.4933 1
0.0451 0.4773 1
0.1038 0.3554 1
0.0032 0.4752 1
0.0533 0.4687 1
0.0092 0.4933 1
0.1007 0.4773 1
0.1357 0.4933 1
0.0668 0.3979 1
0.0691 0.2757 1
0.0926 0.5167 1
0.1224 0.4933 1
0.006 0.445 1
0.0032 0.4752 1
0.0032 0.4752 1
0.0825 0.5576 1
0.0721 0.5568 1
0.0115 0.3243 0.1689
0.0723 0.5356 1
0.0032 0.423 1
0.0701 0.5537 1
0.0032 0.4752 1
0.0032 0.4752 1
0.0032 0.4699 1
0.1329 0.5579 1
0.0032 0.4752 1
0.0993 0.4953 1
0.1057 0.3309 0.9059
0.0032 0.4752 1
0.0107 0.5232 1
0.069 0.4214 1
0.0032 0.4481 0.5691
0.0032 0.4752 1
0.0438 0.5556 1
0.0032 0.4752 1
0.1463 0.4953 1
0.0764 0.4933 1
0.0641 0.4752 1
0.0321 0.3869 1
0.1195 0.512 1
0.0032 0.3373 1
0.0032 0.3559 0.2879
0.0242 0.4933 1
0.0064 0.4608 1
0.0032 0.4752 1
0.0032 0.4752 1
0.029 0.4503 0.9591
0.4107 0.5583 1
0.003 0.2924 1
0.1038 0.3554 1
0.0176 0.5244 1
0.0142 0.4773 1
0.024 0.473 1
0.0349 0.4727 1
0.0515 0.4663 1
0.0696 0.2797 1
0.1115 0.4773 1
0.0054 0.2699 1
0.0032 0.2625 1
0.0405 0.5331 1
0.0033 0.4653 1
0.1222 0.4953 1
0.0032 0.4752 1
0.067 0.4811 1
0.0032 0.443 1
0.0668 0.3979 1
0.0142 0.4752 1
0.0028 0.4773 1
0.0032 0.4752 1
0.0019 0.473 1
0.1421 0.5509 1
0.0032 0.3354 1
0.0312 0.473 1
0.0027 0.2707 0.2144
0.0177 0.2918 1
0.0169 0.4773 1
0.0702 0.4281 1
0.0616 0.4773 1
0.0227 0.444 1
0.012 0.4773 1
0.0032 0.4752 1
0.1009 0.4752 1
0.0032 0.473 0.4146
0.0106 0.4773 1
0.031 0.5209 1
0.034 0.4726 1
0.006 0.473 1
0.0185 0.4351 1
0.0787 0.5164 1
0.0139 0.473 1
0.0944 0.465 1
0.0446 0.4654 1
0.0032 0.4752 1
0.0092 0.4752 1
0.0677 0.2857 1
0.0106 0.4773 1
0.0026 0.4411 1
0.1038 0.3554 1
0.0032 0.4752 1
0.0481 0.4902 1
0.0062 0.4752 0.5663
0.0032 0.473 1
0.0666 0.554 1
0.0032 0.2685 1
0.0703 0.4739 1
0.0032 0.4752 1
0.0062 0.473 1
0.1117 0.4885 1
0.0534 0.4714 1
0.1057 0.3312 0.9059
0.0032 0.4752 1
0.0416 0.384 0.315
0.0032 0.443 1
0.0701 0.5064 1
0.126 0.4953 1
0.0159 0.4752 1
0.1068 0.5274 1
0.0032 0.3559 0.2879
0.0275 0.4953 1
0.0697 0.2522 1
0.0776 0.5356 1
0.0026 0.274 0.3136
0.0032 0.4752 1
0.0032 0.4752 1
0.0032 0.4741 1
0.1402 0.5581 1
0.0027 0.2646 0.2112
0.0776 0.5356 1
0.1135 0.5237 1
0.1513 0.5463 1
0.0723 0.5367 1
0.0032 0.473 0.5068
0.0081 0.3215 1
0.043 0.4953 1
0.2282 0.3909 1
0.0028 0.4773 1
0.0032 0.4752 1
0.0688 0.5538 1
0.0032 0.4752 1
0.0032 0.4752 1
0.0032 0.4752 1
0.0774 0.4646 1
0.1496 0.5521 1
0.0948 0.5447 1
0.0032 0.4752 1
0.0068 0.463 1
0.132 0.4773 1
0.0113 0.473 1
0.0963 0.33 1
0.0056 0.4752 1
0.0032 0.4773 0.4678
0.0032 0.3354 1
0.0633 0.4773 1
0.0027 0.2646 0.2112
0.0032 0.443 0.5691
0.0745 0.5423 1
0.1329 0.5579 1
0.0405 0.5331 1
0.0564 0.4773 1
0.0032 0.4752 1
0.0578 0.4872 1
0.0601 0.4738 1
0.0834 0.4741 1
0.0672 0.4882 1
0.0726 0.474 1
0.0032 0.4331 1
0.0032 0.4752 1
0.0159 0.4752 1
0.0064 0.4608 1

Assayability

Assay information

No assay information for this target.

Reagent availability

No reagent availability information for this target.

Bibliographic References

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Gene identifier TGME49_294820 (Toxoplasma gondii), type I fatty acid synthase, putative
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