Escherichia coli K-12 MG1655: b2022
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Entry
b2022 CDS
T00007
Symbol
hisB
Name
(RefSeq) imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase
KO
K01089
imidazoleglycerol-phosphate dehydratase / histidinol-phosphatase [EC:
4.2.1.19
3.1.3.15
]
Organism
eco
Escherichia coli K-12 MG1655
Pathway
eco00340
Histidine metabolism
eco01100
Metabolic pathways
eco01110
Biosynthesis of secondary metabolites
eco01230
Biosynthesis of amino acids
Module
eco_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
eco00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
b2022 (hisB)
Enzymes [BR:
eco01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.15 histidinol-phosphatase
b2022 (hisB)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.19 imidazoleglycerol-phosphate dehydratase
b2022 (hisB)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
IGPD
Hydrolase_like
PNK3P
HAD_2
HAD
Hydrolase
HAD_SAK_2
PGP_phosphatase
Motif
Other DBs
NCBI-GeneID:
946552
NCBI-ProteinID:
NP_416526
Pasteur:
hisB
RegulonDB:
ECK120000438
ECOCYC:
EG10445
ASAP:
ABE-0006720
UniProt:
P06987
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All DBs
Position
2093468..2094535
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AA seq
355 aa
AA seq
DB search
MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLKLQKAGYKLVMITNQDGLG
TQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECDCRKPKVKLVERYLAEQAM
DRANSYVIGDRATDIQLAENMGITGLRYDRETLNWPMIGEQLTRRDRYAHVVRNTKETQI
DVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEINVKGDLYIDDHHTVEDTGLALG
EALKIALGDKRGICRFGFVLPMDECLARCALDISGRPHLEYKAEFTYQRVGDLSTEMIEH
FFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFGRTLRQAIRVEGDTLPSSKGVL
NT seq
1068 nt
NT seq
+upstream
nt +downstream
nt
atgagtcagaagtatctttttatcgatcgcgatggaaccctgattagcgaaccgccgagt
gattttcaggtggaccgttttgataaactcgcctttgaaccgggcgtgatcccggaactg
ctgaagctgcaaaaagcgggctacaagctggtgatgatcactaatcaggatggtcttgga
acacaaagtttcccacaggcggatttcgatggcccgcacaacctgatgatgcagatcttc
acctcgcaaggcgtacagtttgatgaagtgctgatttgtccgcacctgcccgccgatgag
tgcgactgccgtaagccgaaagtaaaactggtggaacgttatctggctgagcaagcgatg
gatcgcgctaacagttatgtgattggcgatcgcgcgaccgacattcaactggcggaaaac
atgggcattactggtttacgctacgaccgcgaaaccctgaactggccaatgattggcgag
caactcaccagacgtgaccgttacgctcacgtagtgcgtaataccaaagagacgcagatt
gacgttcaggtgtggctggatcgtgaaggtggcagcaagattaacaccggcgttggcttc
tttgatcatatgctggatcagatcgctacccacggcggtttccgcatggaaatcaacgtc
aaaggcgacctctatatcgacgatcaccacaccgtcgaagataccggcctggcgctgggc
gaagcgctaaaaatcgccctcggagacaaacgcggtatttgccgctttggttttgtgcta
ccgatggacgaatgccttgcccgctgcgcgctggatatctctggtcgcccgcacctggaa
tataaagccgagtttacctaccagcgcgtgggcgatctcagcaccgaaatgatcgagcac
ttcttccgttcgctctcatacaccatgggcgtgacgctacacctgaaaaccaaaggtaaa
aacgatcatcaccgtgtagagagtctgttcaaagcctttggtcgcaccctgcgccaggcc
atccgcgtggaaggcgataccctgccctcgtcgaaaggagtgctgtaa
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