Escherichia coli K-12 MG1655: b4006
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Entry
b4006 CDS
T00007
Symbol
purH
Name
(RefSeq) bifunctional AICAR transformylase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
eco
Escherichia coli K-12 MG1655
Pathway
eco00230
Purine metabolism
eco00670
One carbon pool by folate
eco01100
Metabolic pathways
eco01110
Biosynthesis of secondary metabolites
Module
eco_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
eco00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
b4006 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
b4006 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
eco04147
]
b4006 (purH)
Enzymes [BR:
eco01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
b4006 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
b4006 (purH)
Exosome [BR:
eco04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
b4006 (purH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
NSP2_assoc
Motif
Other DBs
NCBI-GeneID:
948503
NCBI-ProteinID:
NP_418434
Pasteur:
purH
RegulonDB:
ECK120000786
ECOCYC:
EG10795
ASAP:
ABE-0013097
UniProt:
P15639
LinkDB
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Position
complement(4205943..4207532)
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AA seq
529 aa
AA seq
DB search
MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGF
PEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLE
DAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAF
EHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKLDMRYGENSHQQAAFYI
EENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSI
LDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQ
NVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTKRQPSEQELRDALFC
WKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFP
FRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
NT seq
1590 nt
NT seq
+upstream
nt +downstream
nt
atgcaacaacgtcgtccagtccgccgcgctctgctcagtgtttctgacaaagccggtatc
gtcgaattcgcccaggcactttccgcacgcggtgtggagctgctgtctacagggggcact
gcccgtctgttagcagaaaaaggtctgccggtaaccgaagtttccgattacaccggtttc
ccggagatgatggatggacgcgtgaagaccctgcatccgaaagtacatggtggcattctg
ggccgtcgcggccaggacgatgccattatggaagaacatcagatccagcctatcgatatg
gtggttgttaacctgtatccgttcgcccagaccgtggcccgtgaaggttgctcgctggaa
gatgcggttgagaacatcgatatcggcggcccaacgatggtgcgctccgccgccaagaac
cataaagatgtcgcaatcgtggtgaagagcagcgactatgacgccattattaaagagatg
gatgacaacgaaggatcgctgacgcttgcaacccgtttcgacctcgccatcaaagccttc
gaacacactgccgcctacgacagcatgattgccaactacttcggcagcatggttccggct
taccacggtgaaagcaaagaagccgccggtcgcttcccacgcacgctgaacctgaacttc
attaagaagctggatatgcgttacggcgagaacagccaccagcaggctgccttctatata
gaagagaatgtgaaagaagcctccgttgctaccgcaacccaggttcagggtaaagccctc
tcttataacaacatcgccgataccgatgcggcgctggagtgcgtgaaagagttcgccgag
ccggcatgtgtgattgtgaagcacgccaacccttgcggcgtggctatcggcaattccatt
cttgatgcttacgatcgcgcgtacaaaaccgacccaacctccgcattcggcggcatcatt
gcctttaaccgcgagctggatgcggaaaccgcacaggccatcatttctcgtcagtttgtc
gaagtgattattgcgccgtccgccagcgaagaagccctgaaaatcaccgccgccaaacag
aacgtacgcgttctgacctgcggtcagtggggcgagcgtgttccgggcctcgatttcaaa
cgcgtgaacggcggtctgctggttcaggatcgtgacctggggatggtcggtgcggaagaa
ctgcgcgtggtgaccaaacgtcagccgagcgaacaggaactgcgtgatgcgctgttctgc
tggaaggtggcgaagtttgtgaaatccaacgctatcgtctatgccaaaaacaatatgact
atcggcattggcgcgggccagatgagccgcgtgtactccgcaaaaatcgccggtattaaa
gcggccgatgaaggcctggaagtgaaaggttcctcgatggcttctgacgcgttcttcccg
ttccgcgacggtattgatgccgccgccgctgcgggcgtgacctgcgtaatccagcctggc
ggttctatccgtgatgacgaagtgattgccgccgccgacgagcacggtattgcgatgctc
ttcaccgacatgcgccacttccgccattaa
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