KEGG   Homo sapiens (human): 5901
Entry
5901              CDS       T01001                                 
Symbol
RAN, ARA24, Gsp1, TC4
Name
(RefSeq) RAN, member RAS oncogene family
  KO
K07936  GTP-binding nuclear protein Ran
Organism
hsa  Homo sapiens (human)
Pathway
hsa03008  Ribosome biogenesis in eukaryotes
hsa03013  Nucleocytoplasmic transport
hsa03250  Viral life cycle - HIV-1
hsa05166  Human T-cell leukemia virus 1 infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    5901 (RAN)
   03008 Ribosome biogenesis in eukaryotes
    5901 (RAN)
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    5901 (RAN)
 09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    5901 (RAN)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    5901 (RAN)
   03009 Ribosome biogenesis [BR:hsa03009]
    5901 (RAN)
   03016 Transfer RNA biogenesis [BR:hsa03016]
    5901 (RAN)
   03036 Chromosome and associated proteins [BR:hsa03036]
    5901 (RAN)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5901 (RAN)
   04031 GTP-binding proteins [BR:hsa04031]
    5901 (RAN)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    Ran-mediated transport factors
     5901 (RAN)
Ribosome biogenesis [BR:hsa03009]
 Eukaryotic type
  Pre-40S particles
   Export and cytoplasmic maturation factors
    5901 (RAN)
  Pre-60S particles
    5901 (RAN)
Transfer RNA biogenesis [BR:hsa03016]
 Eukaryotic type
  tRNA transport factors
   tRNA export factors
    5901 (RAN)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Centrosome duplication proteins
    Regulators of centriole replication
     5901 (RAN)
   Spindle formation proteins
    5901 (RAN)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   5901 (RAN)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Ran Family
   Ran
    5901 (RAN)
SSDB
Motif
Pfam: Ras Roc Arf MMR_HSR1 GTP_EFTU Gtr1_RagA RNA_helicase G-alpha Pox_A32 ArgoMid AAA_24 Septin AAA_7 AAA_16 SRPRB TsaE DUF5906 AAA_22 AAA_33
Other DBs
NCBI-GeneID: 5901
NCBI-ProteinID: NP_006316
OMIM: 601179
HGNC: 9846
Ensembl: ENSG00000132341
UniProt: P62826
Structure
Position
12:130872066..130877678
AA seq 216 aa
MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIK
FNVWDTAGQEKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLC
GNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMP
ALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
NT seq 651 nt   +upstreamnt  +downstreamnt
atggctgcgcagggagagccccaggtccagttcaaacttgtattggttggtgatggtggt
actggaaaaacgaccttcgtgaaacgtcatttgactggtgaatttgagaagaagtatgta
gccaccttgggtgttgaggttcatcccctagtgttccacaccaacagaggacctattaag
ttcaatgtatgggacacagccggccaggagaaattcggtggactgagagatggctattat
atccaagcccagtgtgccatcataatgtttgatgtaacatcgagagttacttacaagaat
gtgcctaactggcatagagatctggtacgagtgtgtgaaaacatccccattgtgttgtgt
ggcaacaaagtggatattaaggacaggaaagtgaaggcgaaatccattgtcttccaccga
aagaagaatcttcagtactacgacatttctgccaaaagtaactacaactttgaaaagccc
ttcctctggcttgctaggaagctcattggagaccctaacttggaatttgttgccatgcct
gctctcgccccaccagaagttgtcatggacccagctttggcagcacagtatgagcacgac
ttagaggttgctcagacaactgctctcccggatgaggatgatgacctgtga

  All links  
Ontology (7)   
   KEGG BRITE (7)   
Pathway (4)   
   KEGG PATHWAY (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (126)   
   KEGG ORTHOLOGY (1)   
   RefGene (79)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (41)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (47)   
   RefSeq(nuc) (3)   
   GenBank (22)   
   EMBL (22)   
3D Structure (124)   
   PDB (124)   
Protein domain (19)   
   Pfam (19)   
All databases (334)   

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