KEGG   Homo sapiens (human): 5409
Entry
5409              CDS       T01001                                 
Symbol
PNMT, PENT, PNMTase
Name
(RefSeq) phenylethanolamine N-methyltransferase
  KO
K00553  phenylethanolamine N-methyltransferase [EC:2.1.1.28]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00350  Tyrosine metabolism
hsa01100  Metabolic pathways
Module
hsa_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Network
nt06028  Dopamine and serotonin metabolism
  Element
N01550  Adrenaline metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    5409 (PNMT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.28  phenylethanolamine N-methyltransferase
     5409 (PNMT)
SSDB
Motif
Pfam: NNMT_PNMT_TEMT Methyltransf_23 Methyltransf_12 Methyltransf_11
Other DBs
NCBI-GeneID: 5409
NCBI-ProteinID: NP_002677
OMIM: 171190
HGNC: 9160
Ensembl: ENSG00000141744
UniProt: P11086
Structure
Position
17:39668019..39670475
AA seq 282 aa
MSGADRSPNAGAAPDSAPGQAAVASAYQRFEPRAYLRNNYAPPRGDLCNPNGVGPWKLRC
LAQTFATGEVSGRTLIDIGSGPTVYQLLSACSHFEDITMTDFLEVNRQELGRWLQEEPGA
FNWSMYSQHACLIEGKGECWQDKERQLRARVKRVLPIDVHQPQPLGAGSPAPLPADALVS
AFCLEAVSPDLASFQRALDHITTLLRPGGHLLLIGALEESWYLAGEARLTVVPVSEEEVR
EALVRSGYKVRDLRTYIMPAHLQTGVDDVKGVFFAWAQKVGL
NT seq 849 nt   +upstreamnt  +downstreamnt
atgagcggcgcagaccgtagccccaatgcgggcgcagcccctgactcggccccgggccag
gcggcggtggcttcggcctaccagcgcttcgagccgcgcgcctacctccgcaacaactac
gcgccccctcgcggggacctgtgcaacccgaacggcgtcgggccgtggaagctgcgctgc
ttggcgcagaccttcgccaccggtgaagtgtccggacgcaccctcatcgacattggttca
ggccccaccgtgtaccagctgctcagtgcctgcagccactttgaggacatcaccatgaca
gatttcctggaggtcaaccgccaggagctggggcgctggctgcaggaggagccgggggcc
ttcaactggagcatgtacagccaacatgcctgcctcattgagggcaagggggaatgctgg
caggataaggagcgccagctgcgagccagggtgaaacgggtcctgcccatcgacgtgcac
cagccccagcccctgggtgctgggagcccagctcccctgcctgctgacgccctggtctct
gccttctgcttggaggctgtgagcccagatcttgccagctttcagcgggccctggaccac
atcaccacgctgctgaggcctggggggcacctcctcctcatcggggccctggaggagtcg
tggtacctggctggggaggccaggctgacggtggtgccagtgtctgaggaggaggtgagg
gaggccctggtgcgtagtggctacaaggtccgggacctccgcacctatatcatgcctgcc
caccttcagacaggcgtagatgatgtcaagggcgtcttcttcgcctgggctcagaaggtt
gggctgtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (12)   
   RefSeq(nuc) (4)   
   GenBank (4)   
   EMBL (4)   
3D Structure (44)   
   PDB (44)   
Protein domain (4)   
   Pfam (4)   
All databases (99)   

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