KEGG   Homo sapiens (human): 6787
Entry
6787              CDS       T01001                                 
Symbol
NEK4, NRK2, STK2, pp12301
Name
(RefSeq) NIMA related kinase 4
  KO
K08857  serine/threonine-protein kinase Nek1/4/5 [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    6787 (NEK4)
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    6787 (NEK4)
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins [BR:hsa03037]
    6787 (NEK4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     6787 (NEK4)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  NEK family
   6787 (NEK4)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    6787 (NEK4)
Cilium and associated proteins [BR:hsa03037]
 Primary cilia and associated proteins
  Other primary cilia associated proteins
   6787 (NEK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Kinase-like Kdo RIO1 ABC1
Other DBs
NCBI-GeneID: 6787
NCBI-ProteinID: NP_003148
OMIM: 601959
HGNC: 11399
Ensembl: ENSG00000114904
UniProt: P51957 Q05DF6
Position
3:complement(52708444..52770940)
AA seq 841 aa
MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLG
SSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
KESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVE
VLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMN
F
NT seq 2526 nt   +upstreamnt  +downstreamnt
atgcccctggccgcctactgctacctgcgggtcgtgggcaaggggagctatggagaggtg
acgcttgtgaagcaccggcgggacggcaagcagtatgtcatcaaaaaactgaacctccga
aatgcctctagccgagagcggcgagctgctgaacaggaagcccagctcttgtctcagttg
aagcatcccaacattgtcacctacaaggagtcatgggaaggaggagatggtctgctctac
attgtcatgggcttctgtgaaggaggtgatttgtaccgaaagctcaaggagcagaaaggg
cagcttctgcctgagaatcaggtggtagagtggtttgtacagatcgccatggctttgcag
tatttacatgaaaaacacatccttcatcgagatctgaaaactcaaaatgtcttcctaaca
agaacaaacatcatcaaagtaggggacctaggaattgcccgagtgttagagaaccactgt
gacatggctagcaccctcattggcacaccctactacatgagccctgaattgttctcaaac
aaaccctacaactataagtctgatgtttgggctctaggatgctgtgtctatgaaatggcc
accttgaagcatgctttcaatgcaaaagatatgaattctttagtttatcggattattgaa
ggaaagctgccaccaatgccaagagattacagcccagagctggcagaactgataagaaca
atgctgagcaaaaggcctgaagaaaggccgtctgtgaggagcatcctgaggcagccttat
ataaagcggcaaatctccttctttttggaggccacaaagataaaaacctccaaaaataac
attaaaaatggtgactctcaatccaagccttttgctacagtggtttctggagaggcagaa
tcaaatcatgaagtaatccacccccaaccactctcttctgagggctcccagacatatata
atgggtgaaggcaaatgtttgtcccaggagaaacccagggcctctggtctcttgaagtca
cctgccagtctgaaagcccatacctgcaaacaggacttgagcaataccacagaactagcc
acaatcagtagcgtaaatattgacatcttacctgcaaaagggagggattcagtgagtgat
ggctttgttcaggagaatcagccaagatatttggatgcctctaatgagttaggaggtata
tgcagtatttctcaagtggaagaggagatgctgcaggacaacactaaatccagtgcccag
cctgaaaacctgattcccatgtggtcctctgacattgtcactggggaaaagaatgaacca
gtgaagcctctgcagcccctaatcaaagaacaaaagccaaaggaccagagtcttgccctg
tcgcccaagctggagtgcagtggcacaatcttggctcacagcaacctccgcctcctgggt
tcaagtgattctccagcctcagcctcccgagtagctgggattacaggcgtgtgccaccac
gcccaggatcaagttgctggtgaatgtattatagaaaaacagggcagaatccacccagat
ttacagccacacaactctgggtctgaaccttccctgtctcgacagcgacggcaaaagagg
agagaacagactgagcacagaggggaaaagagacaggtccgcagagatctctttgctttc
caagagtcgcctcctcgatttttgccttctcatcccattgttgggaaagtggatgtcaca
tcaacacaaaaagaggctgaaaaccaacgtagagtggtcactgggtctgtgagcagttca
aggagcagtgagatgtcatcatcaaaggatcgaccattatcagccagagagaggaggcga
ctaaagcagtcacaggaagaaatgtcctcttcaggcccttcagtgaggaaagcgtctctg
agtgtagcagggccaggaaaaccccaggaagaagaccagcccttgcctgcccgacggctc
tcctctgactgcagcgtcactcaggaaaggaaacagattcattgtctgtctgaggatgag
ttaagttcttctacaagttcaactgataagtcagatggggattacggggaagggaaaggt
cagacaaatgaaattaatgccttggtacaattgatgactcagaccctgaaactggattct
aaagagagctgtgaagatgtcccggtagcaaacccagtgtcagaattcaaacttcatcgg
aaatatcgggacacactgatacttcatgggaaggttgcagaagaggcagaggaaatccat
tttaaagagctaccttcagctattatgccaggttctgaaaagatcaggagactagttgaa
gtcttgagaactgatgtaattcgtggcctgggagttcagcttttagagcaggtgtatgat
cttttggaggaggaggatgaatttgatagagaggtacgtttgcgggagcacatgggtgaa
aagtatacaacttacagtgtgaaagctcgccagttgaaattttttgaagaaaacatgaat
ttttga

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Ontology (5)   
   KEGG BRITE (5)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (29)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (20)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (17)   
DNA sequence (37)   
   RefSeq(nuc) (17)   
   GenBank (10)   
   EMBL (10)   
Protein domain (7)   
   Pfam (7)   
All databases (101)   

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