Saccharomyces cerevisiae (budding yeast): YDR232W
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Entry
YDR232W CDS
T00005
Symbol
HEM1, CYD1, OLE3
Name
(RefSeq) 5-aminolevulinate synthase
KO
K00643
5-aminolevulinate synthase [EC:
2.3.1.37
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00260
Glycine, serine and threonine metabolism
sce00860
Porphyrin metabolism
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01240
Biosynthesis of cofactors
Module
sce_M00868
Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
YDR232W (HEM1)
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
YDR232W (HEM1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
sce01007
]
YDR232W (HEM1)
Enzymes [BR:
sce01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.37 5-aminolevulinate synthase
YDR232W (HEM1)
Amino acid related enzymes [BR:
sce01007
]
Aminotransferase (transaminase)
Class II
YDR232W (HEM1)
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GFIT
Motif
Pfam:
Aminotran_1_2
Cys_Met_Meta_PP
Aminotran_5
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
851818
NCBI-ProteinID:
NP_010518
SGD:
S000002640
UniProt:
P09950
Structure
PDB
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Position
IV:927452..929098
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AA seq
548 aa
AA seq
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MQRSIFARFGNSSAAVSTLNRLSTTAAPHAKNGYATATGAGAAAATATASSTHAAAAAAA
AANHSTQESGFDYEGLIDSELQKKRLDKSYRYFNNINRLAKEFPLAHRQREADKVTVWCS
NDYLALSKHPEVLDAMHKTIDKYGCGAGGTRNIAGHNIPTLNLEAELATLHKKEGALVFS
SCYVANDAVLSLLGQKMKDLVIFSDELNHASMIVGIKHANVKKHIFKHNDLNELEQLLQS
YPKSVPKLIAFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGLYGPHGAGVAEHC
DFESHRASGIATPKTNDKGGAKTVMDRVDMITGTLGKSFGSVGGYVAASRKLIDWFRSFA
PGFIFTTTLPPSVMAGATAAIRYQRCHIDLRTSQQKHTMYVKKAFHELGIPVIPNPSHIV
PVLIGNADLAKQASDILINKHQIYVQAINFPTVARGTERLRITPTPGHTNDLSDILINAV
DDVFNELQLPRVRDWESQGGLLGVGESGFVEESNLWTSSQLSLTNDDLNPNVRDPIVKQL
EVSSGIKQ
NT seq
1647 nt
NT seq
+upstream
nt +downstream
nt
atgcaacgctccatttttgcgaggttcggtaactcctctgccgctgtttccacactgaat
aggctgtccacgacagccgcaccacatgcgaaaaatggctatgccaccgctactggtgct
ggtgccgctgctgccactgccacagcgtcatcaacacatgcagcagcagcagcagccgct
gctgccaaccattccacccaggagtcgggtttcgattacgaaggcctgatagattccgaa
ctgcagaagaaaagacttgacaaatcgtacagatatttcaacaatatcaaccgattggcc
aaggagttccccctagctcatcgccagagagaggcggacaaggtcaccgtttggtgttcc
aacgactatttagcactttccaagcaccctgaggtattggacgccatgcataaaactatc
gacaagtatggttgtggtgccggtggtacaagaaacattgctggccataacatccccact
ttgaatctggaagccgaattggccactttacacaagaaggaaggtgccttagttttttcg
tcatgttacgtagccaacgatgccgtcttatccctactgggtcaaaagatgaaggacttg
gtgattttctccgacgaactcaaccatgcgtccatgattgtcggtattaagcatgctaac
gtaaaaaaacacattttcaaacataatgacttgaacgaattggaacaactgctccagtca
taccccaaatccgttcctaaactaattgctttcgaatcagtatattctatggccggttca
gtggccgacatagaaaaaatttgcgacttggccgacaaatacggtgctttgaccttcttg
gatgaagtacatgcggtcggcctgtacggccctcacggtgcaggtgttgcagaacattgt
gattttgaaagtcaccgtgcaagtggtattgctaccccaaagaccaatgacaagggcggc
gcgaagactgtgatggaccgtgtcgacatgatcaccggcactttaggtaagtctttcggt
agcgtaggtggctacgtcgcagcctctaggaaattgatcgattggttcagatcgtttgca
cctggtttcattttcaccacgactttaccaccttcagttatggcaggcgctaccgcagca
attagataccaacgttgccacatcgacctaagaacctcgcaacagaaacataccatgtac
gtaaagaaagctttccatgagttgggcattccagttattccaaatccttctcatatcgtc
ccagtgttgattggtaatgctgatttggctaagcaagcttctgacatcttaatcaataag
catcaaatctacgtacaagctatcaacttccctacggttgctcgcggtaccgaaagattg
agaattaccccaacgccaggtcacaccaacgatttatctgacatcttaatcaatgcagtt
gatgatgtgttcaatgagctacagttaccacgtgtcagagactgggaaagccaaggtggc
ttattgggtgttggagagagcggatttgtggaagagtctaacttatggacatcaagccaa
ctatctttaactaatgacgacttgaaccctaatgttagagaccccatcgttaaacaacta
gaggtttctagtggtatcaagcagtaa
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