Saccharomyces cerevisiae (budding yeast): YOR278W
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Entry
YOR278W CDS
T00005
Symbol
HEM4, SLU2
Name
(RefSeq) uroporphyrinogen-III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce00860
Porphyrin metabolism
sce01100
Metabolic pathways
sce01110
Biosynthesis of secondary metabolites
sce01240
Biosynthesis of cofactors
Module
sce_M00868
Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
YOR278W (HEM4)
Enzymes [BR:
sce01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
YOR278W (HEM4)
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Motif
Pfam:
HEM4
Motif
Other DBs
NCBI-GeneID:
854452
NCBI-ProteinID:
NP_014921
SGD:
S000005804
UniProt:
P06174
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Position
XV:842817..843644
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AA seq
275 aa
AA seq
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MSSRKKVRVLLLKNKTVPIDKYELECRSKAFEPIFVPLIKHTHVIQDFRNVLNTIPNYLN
TINYIIITSQRTVESLNEAIIPTLTSEQKAALLSKTVYTVGPATANFIRRSGFINVKGGE
DAGNGSILADIIIDDLSTDIKACPPSELLFLVGEIRRDIIPKKLHSKGIKVREVVTYKTE
ELSDGFKRFIHAMKECDEDEVFSDWVVVFSPQGTKEITQYLGDSNRLPGSHLRVASIGPT
TKKYLDDNDVTSDVVSPKPDPKSLLDAIELYQRHK
NT seq
828 nt
NT seq
+upstream
nt +downstream
nt
atgtctagtcgtaaaaaagtcagagtattactgctcaagaataaaactgtccccattgat
aaatatgaattggagtgtaggagtaaggcgtttgaacccatattcgtaccgcttattaaa
catacacatgtaattcaagattttagaaatgttttgaataccatcccaaactatttgaat
actatcaattacattattattacctctcaaaggactgtagagtcattgaatgaagcgatc
attcccacattgacaagtgaacaaaaagctgcattgctcagtaaaacagtttatactgta
ggccctgctactgctaacttcatcagaagatcaggtttcattaatgttaaaggtggagaa
gacgctggtaatggttcaatccttgctgatataattattgatgacttgagtacggatatt
aaggcatgcccaccaagtgaactattatttctcgtgggtgaaattagaagagatatcatc
ccaaagaaactccatagcaagggaataaaagtaagagaagtggttacttataaaactgaa
gaattaagcgacggttttaaaagattcatacacgccatgaaagaatgcgatgaggatgaa
gtattctcggactgggtggtagttttcagtccccagggaacgaaagaaattactcagtat
ttgggtgacagtaaccgcctaccaggttcccatctacgggttgcgtccatcggacctacc
actaaaaaatatctggatgataatgatgtaacctctgatgtggtcagtccaaaaccggac
cccaagtcgctattagatgctattgaattataccagcgccataaataa
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