KEGG   Saccharomyces cerevisiae (budding yeast): YDL108W
Entry
YDL108W           CDS       T00005                                 
Symbol
KIN28
Name
(RefSeq) TFIIH complex serine/threonine-protein kinase subunit KIN28
  KO
K02202  cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
Organism
sce  Saccharomyces cerevisiae (budding yeast)
Pathway
sce03022  Basal transcription factors
sce03420  Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:sce00001]
 09120 Genetic Information Processing
  09121 Transcription
   03022 Basal transcription factors
    YDL108W (KIN28)
  09124 Replication and repair
   03420 Nucleotide excision repair
    YDL108W (KIN28)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sce01001]
    YDL108W (KIN28)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:sce03021]
    YDL108W (KIN28)
   03019 Messenger RNA biogenesis [BR:sce03019]
    YDL108W (KIN28)
   03400 DNA repair and recombination proteins [BR:sce03400]
    YDL108W (KIN28)
Enzymes [BR:sce01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     YDL108W (KIN28)
    2.7.11.23  [RNA-polymerase]-subunit kinase
     YDL108W (KIN28)
Protein kinases [BR:sce01001]
 Serine/threonine kinases: CMGC group
  CDK family
   YDL108W (KIN28)
Transcription machinery [BR:sce03021]
 Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIIH
     YDL108W (KIN28)
Messenger RNA biogenesis [BR:sce03019]
 Eukaryotic type
  mRNA processing factors
   5' end processing
    Capping factors
     YDL108W (KIN28)
DNA repair and recombination proteins [BR:sce03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TFIIH complex
     YDL108W (KIN28)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH ABC1 Kinase-like
Other DBs
NCBI-GeneID: 851450
NCBI-ProteinID: NP_010175
SGD: S000002266
UniProt: P06242
Structure
LinkDB
Position
IV:join(267698..267725,267807..268699)
AA seq 306 aa
MKVNMEYTKEKKVGEGTYAVVYLGCQHSTGRKIAIKEIKTSEFKDGLDMSAIREVKYLQE
MQHPNVIELIDIFMAYDNLNLVLEFLPTDLEVVIKDKSILFTPADIKAWMLMTLRGVYHC
HRNFILHRDLKPNNLLFSPDGQIKVADFGLARAIPAPHEILTSNVVTRWYRAPELLFGAK
HYTSAIDIWSVGVIFAELMLRIPYLPGQNDVDQMEVTFRALGTPTDRDWPEVSSFMTYNK
LQIYPPPSRDELRKRFIAASEYALDFMCGMLTMNPQKRWTAVQCLESDYFKELPPPSDPS
SIKIRN
NT seq 921 nt   +upstreamnt  +downstreamnt
atgaaagtgaatatggagtacacaaaggaaaagaaagttggtgagggtacttatgcggtt
gtttacttgggttgtcaacactctactggaagaaagattgctattaaggagatcaaaaca
tccgaatttaaagatggtttagatatgtcagctatccgtgaagttaagtacctccaagaa
atgcagcatccgaacgtcatagaactaatagacatatttatggcttatgataatttaaat
ctcgttctggagttcctaccaactgatctagaggtggtaataaaagacaaatcaatactg
tttacaccagcagatattaaggcatggatgcttatgactttgaggggcgtgtatcattgc
cacagaaatttcattttgcacagggatctgaaaccaaacaatttattattttcacctgat
ggccagataaaagtagcagatttcggtctagcaagggcgataccggccccacatgagata
ctgacaagtaacgtcgtaacaagatggtatagagcgccagaattgttgtttggagctaaa
cattacacatcggctattgatatctggtcagtaggcgttatattcgcggaattaatgcta
aggataccttatttaccaggacagaatgatgtcgatcaaatggaagtaacgttcagggcc
ttagggacacctacagatagagattggcccgaagtttcttcctttatgacgtataacaag
ttacaaatatatccgcccccttcaagagatgaattgaggaaaaggttcattgctgctagc
gaatacgccttagattttatgtgtggaatgctaacgatgaacccacaaaagaggtggacc
gctgttcagtgtttagaaagtgattatttcaaagaattaccaccaccaagtgacccgtct
tcaataaaaatacgtaactga

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