Saccharomyces cerevisiae (budding yeast): YOL021C
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Entry
YOL021C CDS
T00005
Symbol
DIS3, MTR17, RRP44
Name
(RefSeq) exosome catalytic subunit DIS3
KO
K12585
exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
Organism
sce
Saccharomyces cerevisiae (budding yeast)
Pathway
sce03018
RNA degradation
Brite
KEGG Orthology (KO) [BR:
sce00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
YOL021C (DIS3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
sce03019
]
YOL021C (DIS3)
Messenger RNA biogenesis [BR:
sce03019
]
Eukaryotic type
mRNA degradation factors
3'-5' decay
Exosome cofactors
YOL021C (DIS3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RNB
Rrp44_CSD1
Rrp44_S1
PIN_4
OB_Dis3
CSD2
Dis3l2_C_term
OB_RNB
Motif
Other DBs
NCBI-GeneID:
854138
NCBI-ProteinID:
NP_014621
SGD:
S000005381
UniProt:
Q08162
Structure
PDB
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All DBs
Position
XV:complement(282421..285426)
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AA seq
1001 aa
AA seq
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MSVPAIAPRRKRLADGLSVTQKVFVRSRNGGATKIVREHYLRSDIPCLSRSCTKCPQIVV
PDAQNELPKFILSDSPLELSAPIGKHYVVLDTNVVLQAIDLLENPNCFFDVIVPQIVLDE
VRNKSYPVYTRLRTLCRDSDDHKRFIVFHNEFSEHTFVERLPNETINDRNDRAIRKTCQW
YSEHLKPYDINVVLVTNDRLNREAATKEVESNIITKSLVQYIELLPNADDIRDSIPQMDS
FDKDLERDTFSDFTFPEYYSTARVMGGLKNGVLYQGNIQISEYNFLEGSVSLPRFSKPVL
IVGQKNLNRAFNGDQVIVELLPQSEWKAPSSIVLDSEHFDVNDNPDIEAGDDDDNNESSS
NTTVISDKQRRLLAKDAMIAQRSKKIQPTAKVVYIQRRSWRQYVGQLAPSSVDPQSSSTQ
NVFVILMDKCLPKVRIRTRRAAELLDKRIVISIDSWPTTHKYPLGHFVRDLGTIESAQAE
TEALLLEHDVEYRPFSKKVLECLPAEGHDWKAPTKLDDPEAVSKDPLLTKRKDLRDKLIC
SIDPPGCVDIDDALHAKKLPNGNWEVGVHIADVTHFVKPGTALDAEGAARGTSVYLVDKR
IDMLPMLLGTDLCSLKPYVDRFAFSVIWELDDSANIVNVNFMKSVIRSREAFSYEQAQLR
IDDKTQNDELTMGMRALLKLSVKLKQKRLEAGALNLASPEVKVHMDSETSDPNEVEIKKL
LATNSLVEEFMLLANISVARKIYDAFPQTAMLRRHAAPPSTNFEILNEMLNTRKNMSISL
ESSKALADSLDRCVDPEDPYFNTLVRIMSTRCMMAAQYFYSGAYSYPDFRHYGLAVDIYT
HFTSPIRRYCDVVAHRQLAGAIGYEPLSLTHRDKNKMDMICRNINRKHRNAQFAGRASIE
YYVGQVMRNNESTETGYVIKVFNNGIVVLVPKFGVEGLIRLDNLTEDPNSAAFDEVEYKL
TFVPTNSDKPRDVYVFDKVEVQVRSVMDPITSKRKAELLLK
NT seq
3006 nt
NT seq
+upstream
nt +downstream
nt
atgtcagttcccgctatcgcccccagacggaagagacttgcagatggtttaagcgtcact
cagaaggtgtttgtaaggtctcgtaatggaggcgctaccaagatcgtaagagaacactat
ttaagatcggacatcccatgtctttcgagaagttgtaccaagtgtccgcaaattgtcgtc
cccgatgctcaaaatgagttgccgaagttcatcttgtcagattctcccttagaattaagc
gcacccattggtaagcattacgtcgtcttggataccaacgtggtgttacaggcaattgac
cttttagagaatccgaattgttttttcgacgtcattgtcccccagattgtcctagatgaa
gtgagaaacaagtcatatccggtgtacacgagattaagaactctatgcagagatagtgac
gatcataagagattcatcgtgtttcataacgaatttagtgaacatacttttgtggaaagg
cttccaaatgaaacgattaatgacagaaacgacagggctataaggaaaacctgtcaatgg
tatagtgagcacttgaaaccttatgacataaacgtcgttcttgttaccaacgatcgtttg
aatagagaagctgccactaaggaagtggagtccaatataataaccaagagcttggtacag
tatatcgagttactaccaaatgcagacgacatcagagactctattcctcaaatggattct
tttgataaagatcttgaaagggacacattttcagatttcacgttcccggagtactattct
acagcaagagtaatgggtggtttgaaaaatggcgttttgtaccagggcaatattcaaata
tcagagtacaactttctagaaggttcagtgagtttaccaagattttccaaaccagtgtta
attgttgggcagaaaaacctaaatagagcattcaacggtgaccaggttatcgtggaactg
ctacctcaatcagaatggaaggcaccctcatccattgtcttggattctgaacatttcgac
gttaacgataaccccgatattgaggctggcgatgacgatgacaataatgagtcctcttcc
aataccaccgtgatttccgacaagcagcgcaggctgcttgctaaagatgctatgatagct
caaagatcgaaaaaaattcagcccacggcaaaagttgtatatatacaaagaagatcctgg
agacagtacgtcggtcaactagcaccaagttctgttgatccacaaagcagtagtacacag
aatgtcttcgttattttgatggacaaatgtcttccaaaagtcagaatcagaacaaggcgt
gctgctgaattattggataagaggattgtcatttccattgattcgtggcccaccactcat
aaatacccattaggtcactttgtgagagacctcggtacaattgaatctgctcaagctgaa
acagaggccttattgttggagcatgatgttgaatataggcctttttccaagaaagttcta
gaatgtttgcccgcagaaggccacgattggaaggccccaacaaaactggacgatcctgag
gctgtttcaaaggatccattattgacaaaaagaaaggatctcagagataaacttatatgt
agtatcgatcctccaggatgtgttgatattgacgatgccctacatgcgaaaaagcttcca
aacggtaattgggaagttggtgttcatattgctgatgttactcacttcgttaaaccgggc
actgccctggatgcggaaggtgctgcaagaggtacttctgtatatttggtagacaaacgt
attgacatgctgcccatgcttctaggtaccgacctgtgttctctaaaaccatacgttgat
agattcgcattctctgtcatttgggaattggatgatagtgctaatattgtaaatgttaat
tttatgaaatccgtcatcagatctagagaagctttctcatacgaacaagcacaactgaga
attgatgacaaaacccaaaatgatgaattaacgatgggtatgagggctctcttgaaattg
tctgtaaaactgaagcaaaagagactagaggcaggtgccttgaacttagcttctcctgag
gttaaggtccatatggatagtgagacttcagatccaaatgaagtggaaatcaaaaaatta
ctggcgacaaattctttagttgaagaatttatgttgttggctaatatatcagtggcaagg
aagatatacgatgccttccctcaaacggcgatgctaagaagacacgcagctccgccatct
accaattttgaaatcttaaatgaaatgttaaacacaagaaagaatatgtcaatttcgttg
gaatcgtccaaggccttggccgattctttagacaggtgtgtggatcccgaagatccatat
tttaatacattggttcgtatcatgtcgactcgctgtatgatggcagcccaatacttttat
tctggagcttattcttatcctgactttagacactatggtttagccgttgatatctacaca
catttcacatcacctattagacgttactgtgatgttgtggcccatagacaattagcaggt
gccattgggtatgaacccctaagtttgactcatcgtgataagaataaaatggacatgatt
tgcagaaatatcaacagaaagcacagaaacgcccaattcgccggtagggcaagcatagaa
tactatgtcgggcaagtaatgaggaataacgagtccacagaaactggatatgttattaag
gtatttaataatggtatagtcgtactggttcccaagtttggcgtggaaggcttgataaga
ctggataatttgactgaggatcctaactcagccgcttttgatgaggtggaatacaaatta
acctttgtgcctacaaattcagataaaccgagggatgtttacgttttcgataaggtcgaa
gttcaagttaggtcggtgatggatccaattactagcaagcgtaaggcagaattattgtta
aaatag
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