TDR Targets

Detailed view for LOAG_13432

Basic information

TDR Targets ID: 948347
Loa Loa (eye worm), CYP4Cod1
Source Database / ID: KEGG

pI: 7.2558 | Length (AA): 354 | MW (Da): 40558 | Paralog Number: 3

Signal peptide: N | GPI Anchor: N | Predicted trans-membrane segments: 0

Druggability Group : DG2

Targets have been classified into druggability groups (DG) according to their druggability score in network driven prioritizations. DGs range from 1 to 5; the higher the group number, the higher the chance of the target to be druggable

Network

Pfam domains

PF00067 Cytochrome P450

Gene Ontology

Mouse over links to read term descriptions.

GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 heme binding
GO:0005506 iron ion binding
GO:0055114 oxidation reduction

Metabolic Pathways

This gene is not mapped to any metabolic pathway in KEGG.

Structural information

Modbase 3D models:

There are 3 models calculated for this protein. More info on these models, including the models themselves is available at: Modbase

Target Beg	Target End	Template	Template Beg	Template End	Identity	Evalue	Model Score	MPQS	zDope
1	353	6dwm (C)	66	424	24.00	0.00000000019	1	1.16258	0.67
12	354	6c93 (A)	78	418	34.00	0	1	1.34933	0.12
248	352	4lxj (A)	317	422	31.00	0.00003	1	0.65901	-0.2

Help me make sense of these data.

Target Beg: first modeled residue
Target End: last modeled residue
Template: template structure used for modelling (PDB accession and chain)
Template Beg: first template residue in target-template alignment
Template End: last template residue in target-template alignment
Identity: sequence identity
Evalue: E value for target-template hit
Model Score: GA341 score (>0.7 for reliable model)
MPQS: ModPipe Quality Score (>1.1 for reliable model)
zDope: zDope Score (negative for reliable model)

A more detailed description of these scores is available at the Modbase Model Evaluation Help Pages, and in the papers referenced therein.

PDB Structures:

No structure availble in the PDB for this protein

Expression

No expression data available for this gene

Orthologs

Ortholog group members (OG5_126554)

Species	Accession	Gene Product
Arabidopsis thaliana	AT3G14630	cytochrome P450, family 72, subfamily A, polypeptide 9
Arabidopsis thaliana	AT2G46950	cytochrome P450, family 709, subfamily B, polypeptide 2
Arabidopsis thaliana	AT4G27710	cytochrome P450, family 709, subfamily B, polypeptide 3
Arabidopsis thaliana	AT1G67110	cytokinin hydroxylase
Arabidopsis thaliana	AT3G14610	cytochrome P450, family 72, subfamily A, polypeptide 7
Arabidopsis thaliana	AT5G23190	cytochrome P450 86B1
Arabidopsis thaliana	AT1G75130	cytochrome P450, family 721, subfamily A, polypeptide 1
Arabidopsis thaliana	AT1G69500	cytochrome P450, family 704, subfamily B, polypeptide 1
Arabidopsis thaliana	AT3G14640	cytochrome P450, family 72, subfamily A, polypeptide 10
Arabidopsis thaliana	AT2G26710	cytochrome P450 734A1
Arabidopsis thaliana	AT3G14680	cytochrome P450, family 72, subfamily A, polypeptide 14
Arabidopsis thaliana	AT3G14650	cytochrome P450, family 72, subfamily A, polypeptide 11
Arabidopsis thaliana	AT5G52400	cytochrome P450, family 715, subfamily A, polypeptide 1
Arabidopsis thaliana	AT5G38450	cytochrome P450, family 735, subfamily A, polypeptide 1
Arabidopsis thaliana	AT3G14660	cytochrome P450, family 72, subfamily A, polypeptide 13
Arabidopsis thaliana	AT3G14690	cytochrome P450, family 72, subfamily A, polypeptide 15
Arabidopsis thaliana	AT2G46960	cytochrome P450, family 709, subfamily B, polypeptide 1
Arabidopsis thaliana	AT5G08250	cytochrome P450 superfamily protein
Arabidopsis thaliana	AT1G31800	protein LUTEIN DEFICIENT 5
Arabidopsis thaliana	AT3G14620	cytochrome P450, family 72, subfamily A, polypeptide 8
Arabidopsis thaliana	AT3G01900	cytochrome P450, family 94, subfamily B, polypeptide 2
Brugia malayi	Bm1_51195	Cytochrome P450 family protein
Brugia malayi	Bm1_33645	Cytochrome P450 family protein
Candida albicans	CaO19.7683	similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11
Candida albicans	CaO19.7513	cytochrome P450 556
Candida albicans	CaO19.7512	cytochrome P450 56
Candida albicans	CaO19.10	similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11
Candida albicans	CaO19.13150	closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA
Caenorhabditis elegans	CELE_C36A4.6	Protein CYP-25A4
Caenorhabditis elegans	CELE_F28G4.1	Protein CYP-37B1
Caenorhabditis elegans	CELE_Y62E10A.15	Protein CYP-31A5, isoform B
Caenorhabditis elegans	CELE_ZK1320.4	Protein CYP-13A10
Caenorhabditis elegans	CELE_B0331.1	Protein CYP-29A4
Caenorhabditis elegans	CELE_T19B10.1	Protein CYP-29A2
Caenorhabditis elegans	CELE_T10B9.5	Protein CYP-13A3
Caenorhabditis elegans	CELE_T10B9.2	Protein CYP-13A5
Caenorhabditis elegans	CELE_Y38C9B.1	Protein CYP-29A3
Caenorhabditis elegans	CELE_T10B9.4	Protein CYP-13A8
Caenorhabditis elegans	CELE_Y80D3A.5	Protein CYP-42A1
Caenorhabditis elegans	CELE_C36A4.1	Protein CYP-25A1
Caenorhabditis elegans	CELE_C36A4.2	Protein CYP-25A2
Caenorhabditis elegans	CELE_T10B9.10	Protein CYP-13A7
Caenorhabditis elegans	CELE_H02I12.8	Protein CYP-31A2
Caenorhabditis elegans	CELE_F14F7.2	Protein CYP-13A11
Caenorhabditis elegans	CELE_C36A4.3	Protein CYP-25A3
Caenorhabditis elegans	CELE_C26F1.2	Protein CYP-32A1
Caenorhabditis elegans	CELE_F14F7.3	Protein CYP-13A12
Caenorhabditis elegans	CELE_T10B9.1	Protein CYP-13A4
Caenorhabditis elegans	CELE_T10B9.8	Protein CYP-13A1
Caenorhabditis elegans	CELE_Y17G9B.3	Protein CYP-31A3
Caenorhabditis elegans	CELE_Y5H2B.5	Protein CYP-32B1
Caenorhabditis elegans	CELE_F42A6.4	Protein CYP-25A5
Dictyostelium discoideum	DDB_G0272652	cytochrome P450 family protein
Drosophila melanogaster	Dmel_CG1944	CG1944 gene product from transcript CG1944-RA
Drosophila melanogaster	Dmel_CG4486	Cytochrome P450-9b2
Drosophila melanogaster	Dmel_CG3616	Cytochrome P450-9c1
Drosophila melanogaster	Dmel_CG10242	CG10242 gene product from transcript CG10242-RA
Drosophila melanogaster	Dmel_CG2060	Cytochrome P450-4e2
Drosophila melanogaster	Dmel_CG17577	CG17577 gene product from transcript CG17577-RA
Drosophila melanogaster	Dmel_CG14032	CG14032 gene product from transcript CG14032-RA
Drosophila melanogaster	Dmel_CG10843	CG10843 gene product from transcript CG10843-RA
Drosophila melanogaster	Dmel_CG10245	CG10245 gene product from transcript CG10245-RB
Drosophila melanogaster	Dmel_CG10755	Cytochrome P450-4ae1
Drosophila melanogaster	Dmel_CG9438	Cytochrome P450-6a2
Drosophila melanogaster	Dmel_CG2062	Cytochrome P450-4e1
Drosophila melanogaster	Dmel_CG14031	CG14031 gene product from transcript CG14031-RA
Drosophila melanogaster	Dmel_CG1438	Cytochrome P450-4c3
Drosophila melanogaster	Dmel_CG3466	Cytochrome P450-4d2
Drosophila melanogaster	Dmel_CG10243	CG10243 gene product from transcript CG10243-RB
Drosophila melanogaster	Dmel_CG10842	Cytochrome P450-4p1
Drosophila melanogaster	Dmel_CG6730	CG6730 gene product from transcript CG6730-RA
Drosophila melanogaster	Dmel_CG10241	Cytochrome P450-6a17
Drosophila melanogaster	Dmel_CG3656	Cytochrome P450-4d1
Drosophila melanogaster	Dmel_CG10248	Cytochrome P450-6a8
Drosophila melanogaster	Dmel_CG10240	CG10240 gene product from transcript CG10240-RB
Drosophila melanogaster	Dmel_CG11466	CG11466 gene product from transcript CG11466-RA
Drosophila melanogaster	Dmel_CG4485	Cytochrome P450-9b1
Drosophila melanogaster	Dmel_CG4105	Cytochrome P450-4e3
Drosophila melanogaster	Dmel_CG9081	CG9081 gene product from transcript CG9081-RA
Drosophila melanogaster	Dmel_CG1488	CG1488 gene product from transcript CG1488-RB
Drosophila melanogaster	Dmel_CG13977	CG13977 gene product from transcript CG13977-RB
Drosophila melanogaster	Dmel_CG7249	CG7249 gene product from transcript CG7249-RB
Drosophila melanogaster	Dmel_CG10247	CG10247 gene product from transcript CG10247-RA
Drosophila melanogaster	Dmel_CG17970	CG17970 gene product from transcript CG17970-RB
Drosophila melanogaster	Dmel_CG16761	CG16761 gene product from transcript CG16761-RA
Drosophila melanogaster	Dmel_CG2110	CG2110 gene product from transcript CG2110-RA
Drosophila melanogaster	Dmel_CG10246	Cytochrome P450-6a9
Drosophila melanogaster	Dmel_CG3540	CG3540 gene product from transcript CG3540-RA
Homo sapiens	ENSG00000186115	cytochrome P450, family 4, subfamily F, polypeptide 2
Homo sapiens	ENSG00000186377	cytochrome P450, family 4, subfamily X, polypeptide 1
Homo sapiens	ENSG00000142973	cytochrome P450, family 4, subfamily B, polypeptide 1
Homo sapiens	285440	cytochrome P450, family 4, subfamily V, polypeptide 2
Homo sapiens	ENSG00000106258	cytochrome P450, family 3, subfamily A, polypeptide 5
Homo sapiens	ENSG00000021461	cytochrome P450, family 3, subfamily A, polypeptide 43
Homo sapiens	ENSG00000171903	cytochrome P450, family 4, subfamily F, polypeptide 11
Homo sapiens	ENSG00000186529	cytochrome P450, family 4, subfamily F, polypeptide 3
Homo sapiens	ENSG00000171954	cytochrome P450, family 4, subfamily F, polypeptide 22
Homo sapiens	ENSG00000187048	cytochrome P450, family 4, subfamily A, polypeptide 11
Homo sapiens	ENSG00000186526	cytochrome P450, family 4, subfamily F, polypeptide 8
Homo sapiens	ENSG00000186160	cytochrome P450, family 4, subfamily Z, polypeptide 1
Homo sapiens	ENSG00000160870	cytochrome P450, family 3, subfamily A, polypeptide 7
Homo sapiens	ENSG00000186204	cytochrome P450, family 4, subfamily F, polypeptide 12
Homo sapiens	ENSG00000162365	cytochrome P450, family 4, subfamily A, polypeptide 22
Homo sapiens	1576	cytochrome P450, family 3, subfamily A, polypeptide 4
Homo sapiens	ENSG00000160870	CYP3A7-CYP3AP1 readthrough
Leishmania braziliensis	LbrM.27.0100	cytochrome p450-like protein
Leishmania donovani	LdBPK_270090.1	cytochrome p450-like protein
Leishmania infantum	LinJ.27.0090	cytochrome p450-like protein
Leishmania major	LmjF.27.0090	cytochrome p450-like protein
Leishmania mexicana	LmxM.27.0090	cytochrome p450-like protein
Loa Loa (eye worm)	LOAG_15610	hypothetical protein
Loa Loa (eye worm)	LOAG_08165	cytochrome P450 family protein
Loa Loa (eye worm)	LOAG_13432	CYP4Cod1
Loa Loa (eye worm)	LOAG_15249	cytochrome P450 family protein
Mus musculus	ENSMUSG00000084346	cytochrome P450, family 4, subfamily a, polypeptide 30b
Mus musculus	ENSMUSG00000024055	cytochrome P450, family 4, subfamily f, polypeptide 13
Mus musculus	ENSMUSG00000056035	cytochrome P450, family 3, subfamily a, polypeptide 11
Mus musculus	ENSMUSG00000003484	cytochrome P450, family 4, subfamily f, polypeptide 18
Mus musculus	ENSMUSG00000028713	cytochrome P450, family 4, subfamily b, polypeptide 1
Mus musculus	ENSMUSG00000062464	cytochrome P450, family 4, subfamily f, polypeptide 37
Mus musculus	ENSMUSG00000073424	cytochrome P450, family 4, subfamily f, polypeptide 15
Mus musculus	102294	cytochrome P450, family 4, subfamily v, polypeptide 3
Mus musculus	ENSMUSG00000054417	cytochrome P450, family 3, subfamily a, polypeptide 44
Mus musculus	ENSMUSG00000028715	cytochrome P450, family 4, subfamily a, polypeptide 14
Mus musculus	ENSMUSG00000061292	cytochrome P450, family 3, subfamily a, polypeptide 59
Mus musculus	ENSMUSG00000063929	cytochrome P450, family 4, subfamily a, polypeptide 32
Mus musculus	ENSMUSG00000029727	cytochrome P450, family 3, subfamily a, polypeptide 13
Mus musculus	ENSMUSG00000083138	cytochrome P450, family 4, subfamily a, polypeptide 29
Mus musculus	ENSMUSG00000038656	cytochrome P450, family 3, subfamily a, polypeptide 16
Mus musculus	102641312	cytochrome P450 3A41-like
Mus musculus	ENSMUSG00000066071	cytochrome P450, family 4, subfamily a, polypeptide 12a
Mus musculus	ENSMUSG00000024292	cytochrome P450, family 4, subfamily f, polypeptide 14
Mus musculus	ENSMUSG00000075551	cytochrome P450, family 3, subfamily a, polypeptide 41A
Mus musculus	ENSMUSG00000048440	cytochrome P450, family 4, subfamily f, polypeptide 16
Mus musculus	ENSMUSG00000075552	cytochrome P450, family 3, subfamily a, polypeptide 41B
Mus musculus	ENSMUSG00000078597	cytochrome P450, family 4, subfamily a, polypeptide 12B
Mus musculus	ENSMUSG00000070419	cytochrome P450, family 3, subfamily a, polypeptide 57
Mus musculus	ENSMUSG00000066072	cytochrome P450, family 4, subfamily a, polypeptide 10
Mus musculus	ENSMUSG00000090700	cytochrome P450, family 4, subfamily f, polypeptide 40
Mus musculus	ENSMUSG00000029630	cytochrome P450, family 3, subfamily a, polypeptide 25
Mus musculus	320997	cytochrome P450, family 4, subfamily f, polypeptide 39
Mus musculus	ENSMUSG00000091586	cytochrome P450, family 4, subfamily f, polypeptide 17
Mus musculus	ENSMUSG00000028712	cytochrome P450, family 4, subfamily a, polypeptide 31
Mus musculus	102643044	cytochrome P450 3A11-like
Mycobacterium ulcerans	MUL_0604	cytochrome P450 185A4 Cyp185A4
Oryza sativa	9271449	Os01g0627600
Oryza sativa	4326657	Os01g0627500
Oryza sativa	4340370	Os06g0191800
Oryza sativa	4331152	Os02g0817900
Oryza sativa	9268599	Os07g0419000
Oryza sativa	9269428	Os09g0403300
Oryza sativa	4331202	Os02g0824100
Oryza sativa	4326694	Os01g0627400
Oryza sativa	4326663	Os01g0628700
Oryza sativa	9272564	Os01g0627933
Oryza sativa	4344026	Os07g0635700
Oryza sativa	4348947	Os10g0486100
Oryza sativa	4349164	Os10g0524700
Oryza sativa	4332937	Os03g0370900
Oryza sativa	4326929	Os01g0701500
Oryza sativa	9271728	Os01g0701400
Oryza sativa	4336728	Os04g0573900
Oryza sativa	4326664	Os01g0628900
Oryza sativa	4344024	Os07g0635500
Oryza sativa	9269315	Os01g0701300
Oryza sativa	9268939	Os02g0204700
Oryza sativa	4331756	Os03g0168600
Oryza sativa	4341450	Os06g0600400
Oryza sativa	4349165	Os10g0525000
Oryza sativa	4338594	Os05g0372300
Oryza sativa	4324604	Os01g0602400
Oryza sativa	4344023	Os07g0635300
Oryza sativa	4326475	Os01g0349800
Oryza sativa	4344022	Os07g0635200
Oryza sativa	4326660	Os01g0627900
Oryza sativa	9267499	Os01g0627966
Oryza sativa	4324605	Os01g0602500
Oryza sativa	4349166	Os10g0525200
Oryza sativa	4343035	Os07g0419100
Oryza sativa	4343032	Os07g0418500
Oryza sativa	4326659	Os01g0627800
Oryza sativa	4339998	Os06g0129900
Oryza sativa	4340369	Os06g0191700
Schmidtea mediterranea	mk4.002203.00	Cytochrome P450 20A1
Schmidtea mediterranea	mk4.003455.02
Schmidtea mediterranea	mk4.000200.05
Schmidtea mediterranea	mk4.019771.00
Schmidtea mediterranea	mk4.032551.00
Schmidtea mediterranea	mk4.001060.09
Schmidtea mediterranea	mk4.003455.00
Schmidtea mediterranea	mk4.019801.00
Schmidtea mediterranea	mk4.013908.00
Schmidtea mediterranea	mk4.000200.01
Schmidtea mediterranea	mk4.000200.02
Schmidtea mediterranea	mk4.001060.11
Schmidtea mediterranea	mk4.004132.00
Schmidtea mediterranea	mk4.016958.00
Schmidtea mediterranea	mk4.003455.01	Probable cytochrome P450 6a20
Schmidtea mediterranea	mk4.022052.00
Schmidtea mediterranea	mk4.000200.03
Trypanosoma brucei gambiense	Tbg972.3.290	cytochrome P450, putative
Trypanosoma brucei	Tb927.3.680	cytochrome P450, putative
Trypanosoma congolense	TcIL3000_0_21540	cytochrome P450, putative
Trypanosoma cruzi	TcCLB.509231.10	cytochrome P450, putative
Trypanosoma cruzi	TcCLB.509719.40	cytochrome P450, putative

Essentiality

LOAG_13432 has one or more orthologs with essentiality data

Gene/Ortholog	Organism	Phenotype	Source Study
Tb927.3.680	Trypanosoma brucei	no significant loss or gain of fitness in bloodstream forms (3 days)	alsford
Tb927.3.680	Trypanosoma brucei	significant loss of fitness in bloodstream forms (6 days)	alsford
Tb927.3.680	Trypanosoma brucei	no significant loss or gain of fitness in procyclic forms	alsford
Tb927.3.680	Trypanosoma brucei	no significant loss or gain of fitness in differentiation of procyclic to bloodstream forms	alsford
CELE_H02I12.8	Caenorhabditis elegans	embryonic lethal	wormbase
CELE_T10B9.1	Caenorhabditis elegans	slow growth	wormbase
CELE_T10B9.2	Caenorhabditis elegans	slow growth	wormbase
CELE_T10B9.4	Caenorhabditis elegans	embryonic lethal	wormbase
CELE_Y62E10A.15	Caenorhabditis elegans	embryonic lethal	wormbase
CELE_Y80D3A.5	Caenorhabditis elegans	embryonic lethal	wormbase
CELE_Y80D3A.5	Caenorhabditis elegans	larval arrest	wormbase
CELE_Y80D3A.5	Caenorhabditis elegans	sterile	wormbase
CELE_Y17G9B.3	Caenorhabditis elegans	embryonic lethal	wormbase

Show/Hide essentiality data references

shigen

Profiling of E. coli Chromosome (PEC)

National Institute of Genetics, Japan

wormbase

C. elegans RNAi experiments

WormBase web site, http://www.wormbase.org, release WS170

neb

C. elegans RNAi phenotypes

Data obtained from Wormbase WS150, curated by K. Chaudary and T. Carlow, New England Biolabs

yeastgenome

Systematic deletion of yeast genes

Saccharomyces Genome Database

goodall

The Essential Genome of Escherichia coli K-12 (Transposon directed high-throughput mutagenesis)

Goodall, Emily CA, et al. "The essential genome of Escherichia coli K-12." mBio 9.1 (2018): e02096-17.

plasmo

Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.

Bushell, Ellen, et al. "Functional profiling of a Plasmodium genome reveals an abundance of essential genes." Cell 170.2 (2017): 260-272.

nmpdr

Genome-scale essentiality datasets from published studies (M. tuberculosis)

National Microbial Pathogen Data Resource

keio

Systematic single-gene knock-out mutants of E. coli K12

The Keio Collection

alsford

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

Genome Res 2011, 21:915-924

gerdes

Experimental determination and system-level analysis of essential genes in E. coli MG1655

Gerdes et al., J Bacteriol. 2003 185:5673-84

sidik

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.

Sidik, Saima M., et al. "A genome-wide CRISPR screen in toxoplasma identifies essential apicomplexan genes." Cell 166.6 (2016): 1423-1435.

blattner

Systematic mutagenesis of the E. coli (MG1655) genome

J Bacteriol 2004, 186:4921-4930

Phenotypes and Validation (curated)

We have no manually annotated phenotypes for this target. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please contact us.

Annotated validation

No validation data for this target

Associated compounds / Druggability

Known modulators for this target

No chemical compounds associated to this gene

Predicted associations

By orthology with druggable targets

Species	Known druggable target	Linked compounds	Reference
Homo sapiens	cytochrome P450, family 3, subfamily A, polypeptide 5	Compounds	References
Oryctolagus cuniculus	Cytochrome P450 4A4	Compounds	References
Homo sapiens	cytochrome P450, family 3, subfamily A, polypeptide 4	Compounds	References
Homo sapiens	cytochrome P450, family 4, subfamily F, polypeptide 2	Compounds	References
Rattus norvegicus	Cytochrome P450 3A1	Compounds	References

By sequence similarity to non orthologous druggable targets

No additional associated druggable targets

Ranking Plot

Putative Drugs List

Raw	Global	Species
0.007	0.2999	0.2999
0.0904	0.9217	1
0.0043	1	1
0.0028	0.4492	0.5033
0.0012	0.5	0.5
0.000218985	0.5	0.5
0.0036	0.7463	0.8318
0.0202	0.3625	0.3573
0.00248392	1	1
0.0278	0.3649	0.3684
0.0015	1	1
0.0015	0.481	0.4046
0.0039	0.427	0.4309
0.0221	1	1
0.0028	1	1
0.0023	1	1
0.033	0.3572	0.3572
0.0016	0.7099	0.7099
0.0063	0.5	0.5
0.0086	0.3067	0.3067
0.01	1	1
0.0012	1	1
0.0012	0.5	0.5
0.0004	0.5	0.5
0.0018	1	1
0.0024	1	1
0.0019	0.4068	0.4068
0.0202	0.5069	0.4972
0.0024	1	1
0.0175	0.257	0.2483
0.00248392	1	1
0.0015	1	1
0.0391	0.7901	1
0.0064	0.256	0.2473
0.0454	0.2999	0.2991
0.0246	0.2927	0.2927
0.0015	0.5	0.5
0.0072	1	1
0.0038	0.5102	0.3326
0.05	0.2714	0.2713
0.0066	1	1
0.0064	0.3518	0.3518
0.0019	0.4592	0.4592
0.0023	0.3815	0.3815
0.0032	0.5	0.5
0.0092	1	1
0.0071	0.5	0.5
0.0653	0.7763	1
0.1138	0.2596	0.2592
0.0015	1	1
0.0018	0.4068	0.4068
0.0004	0.5	0.5
0.0004	0.5	0.5
0.0197	0.3697	0.3687
0.0086	0.323	0.323
0.0047	0.3084	0.3084
0.0267	0.3402	0.3402
0.0065	1	1
0.0004	0.5	0.5
0.0042	0.5	0.5
0.0027	1	1
0.0025	1	1
0.0078	1	1
0.0324	0.3232	1
0.004	1	1
0.0029	1	1
0.0024	1	1
0.0026	1	1
0.0137	0.267	0.7501
0.0333	0.3449	0.3421
0.0117	0.3535	0.3368
0.0021	1	1
0.0087	0.4426	0.3795
0.0019	1	1
0.0049	1	1
0.0032	1	1
0.0013	0.481	0.4046
0.0015	0.5	0.5
0.0036	0.3046	0.3046
0.00248392	1	1
0.0031	0.2533	0.2533
0.0239	0.2794	0.2794
0.0293	0.318	0.3181
0.0067	0.5	0.5
0.014	0.2837	0.2837
0.005	1	1
0.0076	0.4133	0.4668
0.0014	1	1
0.0057	1	1
0.00245215	0.894779	1
0.0027	0.2572	0.325
0.0018	0.4068	0.4068
0.0122	0.2527	0.2527
0.0217	0.8044	0.9565
0.0312	0.5853	1
0.0034	0.337	0.337
0.0053	1	1
0.0354	0.4291	0.4945
0.0706	0.3684	0.3684
0.0032	1	1
0.00109509	1	1
0.0137	0.2698	0.2694
0.00248392	1	1
0.0004	0.5	0.5
0.0196	0.2792	0.2775
0.0147	0.2647	0.2672
0.0022	0.2508	0.2307
0.0087	0.343	0.343
0.0301	0.3053	0.3053
0.0029	1	1
0.0112	1	1
0.0004	0.5	0.5
0.002	0.5662	0.5662
0.0089	0.4254	0.5837
0.023	0.2781	0.2781
0.0026	0.4133	0.4668
0.0051	0.3845	0.3845
0.0211	0.3096	0.3096
0.0025	1	1
0.0019	1	1
0.0259	0.5252	0.5221
0.008	0.3162	0.3162
0.0015	0.481	0.4046
0.0192	1	1
0.0029	0.2936	0.2936
0.0092	1	1
0.0338	0.2653	0.2653
0.0019	0.2954	0.3336
0.0028	0.2912	0.3164
0.0106	1	1
0.0004	0.5	0.5
0.0353	0.4928	1
0.0015	1	1
0.0016	1	1
0.0029	1	1
0.0019	1	1
0.0023	0.4835	0.4734
0.0064	0.4681	0.4681
0.0066	0.4178	0.4178
0.0023	0.3323	0.3323
0.0092	1	1
0.0218	1	1
0.0029	0.5	0.5
0.0401	0.4273	0.4273
0.0061	0.2564	0.2564
0.0019	0.5	0.5
0.0015	1	1
0.0213	0.2856	0.2856
0.0019	1	1
0.113	0.7737	0.8775
0.0235	0.2973	0.2973
0.014	0.4739	0.4739
0.0004	0.5	0.5
0.0109	0.2608	0.2608
0.0014	1	1
0.0007	1	1
0.0227	0.3071	0.3069
0.0153	0.6617	0.6617
0.0004	0.5	0.5
0.0008	0.5	0.5
0.0048	1	1
0.035	0.4238	0.4238
0.0018	0.4068	0.4068
0.0069	0.2502	0.2101
0.0018	0.4068	0.4068
0.0177	0.3022	0.4483
0.0295	0.2981	0.2981
0.0891	0.3038	0.3036
0.0035	0.4422	1
0.0036	0.7694	0.7694
0.0103	1	1
0.0065	0.3545	0.3545
0.0045	0.5	0.5
0.0004	0.5	0.5
0.0086	1	1
0.0017	0.259	0.2887
0.0052	1	1
0.0163	0.2612	0.254
0.0019	1	1
0.0018	0.4297	0.4297
0.0043	0.2888	0.2888
0.0077	1	1
0.0072	1	1
0.0064	0.3358	0.3358
0.0085	0.3479	0.3479
0.0127	0.281	0.281
0.0074	0.6101	0.6101
0.0019	0.2618	0.2618
0.0004	0.5	0.5
0.0053	1	1
0.0015	1	1
0.0137	1	1
0.0024	0.5	0.5
0.01	0.4592	0.4592
0.0067	1	1
0.0019	0.3005	0.3394
0.0023	0.2767	0.5071
0.0206	1	1
0.0027	1	1
0.0049	1	1
0.0019	0.7046	0.7046
0.0015	1	1
0.005	1	1
0.003	0.2583	0.9367
0.0023	0.5	0.5
0.0013	0.5	0.5
0.000396385	0.5	0.5
0.0212	0.3935	0.3926
0.0032	0.5	0.5
0.004	0.8163	0.9219
0.0015	1	1
0.0018	0.4068	0.4068
0.0265	0.3125	0.4497
0.0085	1	1
0.0031	0.2518	0.2518
0.0756	1	1
0.0059	0.3657	0.3657
0.0116155	1	1
0.0107	0.5037	0.5037
0.0026	0.3603	0.3603
0.0018	0.4068	0.4068
0.0024	1	1
0.0032	0.3535	0.3535
0.002	0.2653	0.2653
0.0137	0.2676	0.2676
0.0019	1	1
0.0086	1	1
0.0019	0.2508	0.2508
0.0019	0.2807	0.2807
0.0019	1	1
0.0004	0.5	0.5
0.0073	1	1
0.0056	0.3757	0.3757
0.0362	0.3492	0.3485
0.0294	0.3297	0.3273
0.0015	0.5	0.5
0.0054	0.3757	0.3757
0.0023	0.5	0.5
0.0348	1	1
0.0019	0.5	0.5
0.0045	0.3782	0.3782
0.0221	1	1
0.0012	1	1
0.0091	1	1
0.0026	0.5	0.5
0.0026	0.3681	0.3681
0.0015	1	1
0.0278	1	1
0.0367	0.3246	1
0.005	0.3302	0.3302
0.0026	0.3999	0.3757
0.0004	0.5	0.5
0.0093	0.3128	0.3128
0.0058	0.5	0.5
0.0019	1	1
0.0023	0.5	0.5
0.005	1	1
0.0225	0.2754	0.2754
0.0974	1	1
0.0015	0.259	0.259
0.0068	0.5	0.5
0.0125	0.2572	0.2856
0.0019	0.3376	0.3376
0.0026	0.3427	0.3427
0.0225	0.2665	0.2665
0.0012	1	1
0.0004	0.5	0.5
0.0015	0.3154	0.3154
0.0024	0.3099	0.3071
0.0004	0.5	0.5
0.0165	0.3391	0.4527
0.0327	0.3118	0.3118
0.0016	1	1
0.0086	1	1
0.0016	0.2512	0.2512
0.0023	0.4133	0.4668
0.0485	1	1
0.0012	1	1
0.0015	1	1
0.0023	0.3815	0.3815
0.0232	0.3136	0.3136
0.0393	1	1
0.0025	1	1
0.0015	0.2508	0.2508
0.0187	0.3349	0.3088
0.1713	0.2583	0.2819
0.0013	1	1
0.0027	0.2908	0.2908
0.0855	1	1
0.0030544	0.280572	0.317658
0.0043	1	1
0.0015	1	1
0.021	0.3081	0.3081
0.0578	0.4641	0.4629
0.0227	0.2903	0.2897
0.0111	1	1
0.0308	0.4471	0.447
0.008	0.3317	0.3317
0.0015	1	1
0.0018	1	1
0.1125	0.3134	0.3134
0.0163	0.2672	0.2672
0.0015	1	1
0.0023	0.4835	0.4734
0.0015	1	1
0.0013	1	1
0.0029	0.3385	0.3134
0.0059	0.4799	0.4799
0.0015	1	1
0.0074	1	1
0.0029	0.3757	0.3757
0.1189	1	1
0.0026	1	1
0.0015	1	1
0.0004	0.5	0.5
0.0022	0.4733	0.4733
0.0016	0.2508	0.2508
0.0107	1	1
0.0028	0.2943	0.2943
0.0016	0.4068	0.4068
0.0019	0.2639	0.2939
0.0239	0.3197	0.3197
0.0027	1	1
0.0179	0.6902	1
0.0112	0.7599	0.7599
0.0016	0.5	0.5
0.0095	0.3033	0.3573
0.0058	0.7201	0.7201
0.0368	1	1
0.0218	1	1
0.0022	0.5	0.5
0.005	0.3443	0.3443
0.0913	0.2671	0.2671
0.0026	0.325	0.325
0.0263	0.3902	0.3902
0.0011	0.5	0.5
0.0083	0.2639	0.2939
0.0004	0.5	0.5
0.0032	0.3757	0.3757
0.0016	1	1
0.0087	1	1
0.0058	0.3607	0.3607
0.0111	0.2543	0.4561
0.0012	0.5	0.5
0.0111	0.4466	0.445
0.0028	1	1
0.0036	1	1
0.0137	0.6151	1
0.0238	0.2786	0.2786
0.00248392	1	1
0.028	0.268	0.2657
0.0793	1	1
0.004	0.3781	0.3781
0.074	0.3446	0.3445
0.0027	1	1
0.0026	0.2696	0.2696
0.0012	0.3544	0.3544
0.0004	0.5	0.5
0.1322	0.2537	0.2537
0.0063	0.3913	0.3913
0.1174	0.2662	0.266
0.0245	0.3143	0.3143
0.1255	1	1
0.0004	0.5	0.5
0.0028	1	1
0.1189	1	1
0.0145	0.2816	0.2806
0.0157	0.293	0.293
0.00249998	0.398153	0.398153
0.0019	0.7046	0.7046
0.1222	0.2735	0.2735
0.0235	0.273	0.3469
0.00248392	1	1
0.0003	0.5	0.5
0.0073	0.2818	0.2818
0.0065	0.2639	0.2939
0.0542	0.4099	0.4079
0.0007	0.5	0.5
0.0004	0.5	0.5
0.0092	1	1
0.0742	1	1
0.0015	1	1
0.0353179	1	1
0.0067	0.5	0.5
0.054	0.5492	1
0.0026	0.3839	0.3839
0.0292	1	1
0.056	0.3675	0.3675
0.011	0.305	0.305
0.0166	0.3293	0.3293
0.0021	0.4733	0.4733
0.0023	0.5	0.5
0.0938	0.6104	0.6944
0.0018	0.4068	0.4068
0.0032	0.2899	0.3415
0.0259	1	1
0.0239	0.3116	0.3116
0.0209	0.2707	0.4286
0.0017	1	1
0.0014	0.5	0.5
0.0016	1	1
0.0015	0.3523	0.3523
0.005	1	1
0.1126	0.7809	1
0.0081	1	1
0.0036	0.3232	0.3139
0.0019	0.2639	0.2939
0.01	0.9783	0.9783
0.0141	0.3413	0.3103
0.0016	0.2653	0.2653
0.0026	0.3137	0.2634
0.0032	1	1
0.0047	0.5	0.5
0.0032	0.3491	0.3491
0.0012	0.3845	0.3845
0.0033	0.5	0.5
0.0097	1	1
0.0314	0.3005	0.3553
0.0074	1	1
0.0137	0.2698	0.2694
0.004	1	1
0.0362	0.3492	0.3485
0.0026	1	1
0.0008	0.4068	0.4068
0.0015	0.5	0.5
0.0058	0.3304	1
0.0004	0.5	0.5
0.0049	1	1
0.0074	1	1
0.0324	0.3076	0.3076
0.0045	0.5	0.5
0.0061	0.3491	0.3491
0.0103	1	1
0.0609	0.2644	0.2644
0.0019	1	1
0.0018	0.5	0.5
0.0244	0.316	0.316
0.0013	1	1
0.0057	0.2717	0.2622
0.0015	0.5	0.5
0.0032	1	1
0.00169346	1	1
0.0858	0.2917	0.2916
0.0004	0.5	0.5
0.0013	0.8285	0.8285
0.0091	0.3483	0.3483
0.0015	1	1
0.0113	0.4206	0.4201
0.0389	0.5693	1
0.003	0.324	0.3779
0.0021	0.2902	0.2653
0.0025	1	1
0.0084	0.5067	1
0.0089	0.4463	0.4463
0.0004	0.5	0.5
0.0015	0.5	0.5
0.0274	0.3125	0.4937
0.0011	1	1
0.0064	0.9126	0.9126
0.0074	0.2962	0.2962
0.0803	0.3082	0.3082
0.1274	0.2586	0.2581
0.0052	0.4385	0.4385
0.0089	0.4051	0.4051
0.1221	0.29	0.29
0.0019	0.293	0.293
0.0093	1	1
0.0015	0.259	0.259
0.0013	0.3523	0.3523
0.0083	0.3704	0.3704
0.0165	1	1
0.0012	0.3523	0.3523
0.00248392	1	1
0.0022	0.325	0.325
0.0028	0.4563	0.4563
0.0224	0.2633	1
0.0044	1	1
0.0015	1	1
0.0057	0.5672	0.6321
0.0015	1	1
0.0037	0.2694	0.2694
0.0094	0.4498	0.4498
0.008	0.2701	0.2353
0.0031	0.4592	0.4592
0.0223	0.2818	0.2818
0.0047	0.6342	0.6342
0.0015	1	1
0.0034	0.2639	0.2939
0.0015	0.7402	0.7402
0.0019	1	1
0.0029	1	1
0.0016	1	1
0.0004	0.5	0.5
0.0014	1	1
0.0019	0.4068	0.4068
0.0351	0.4331	0.9849
0.0205	0.2758	0.2758
0.0007	0.5	0.5
0.0011	0.5	0.5
0.0852	0.271	0.271
0.0022	0.2577	0.2521
0.0137	0.267	0.7501
0.0014	0.3523	0.3523
0.0015	1	1
0.0457	0.475	0.475
0.0015	1	1
0.0051	1	1
0.0019	0.4068	0.4068
0.0612	0.2868	0.2867
0.0031	1	1
0.0118	0.3724	0.403
0.011	0.2983	0.2983
0.0019	0.2756	0.3071
0.0026	0.5	0.5
0.00248392	1	1
0.0524	0.3502	0.3502
0.0012	1	1
0.0517	0.5703	1
0.0052	0.4293	0.3767
0.0129	0.3346	1
0.021	0.2879	0.2879
0.0082	0.2599	0.2599
0.0004	0.5	0.5
0.0015	1	1
0.106	0.2543	0.2543
0.0016	1	1
0.0025	1	1
0.0023	0.3323	0.3323
0.004	0.2572	0.0251
0.0015	1	1
0.0032	0.2924	0.2924
0.0082	1	1
0.0072	0.8926	0.8926
0.0004	0.5	0.5
0.007	0.5713	0.5
0.0013	1	1
0.0012	0.5738	0.5738
0.0464	0.4861	0.4861
0.0016	1	1
0.0056	1	1
0.0046	0.5	0.5
0.0279	0.5276	0.5276
0.0027	0.2869	0.2296
0.0013	1	1
0.0124	0.4045	0.4045
0.0058	0.5019	0.5019
0.0015	1	1
0.0018	0.259	0.2639
0.0177	0.3022	0.4483
0.0293	0.318	0.3181
0.0052	0.3591	0.3591
0.0019	0.2508	0.2508
0.0023	0.325	0.325
0.0112	1	1
0.0024	1	1
0.0099	0.4102	0.4102
0.0047	0.2585	0.5556
0.0023	0.4747	0.4747
0.0024	1	1
0.0333	1	1
0.0004	0.5	0.5
0.0083	0.2785	0.2785
0.0016	0.4068	0.4068
0.0015	1	1
0.0104	0.5	0.5
0.0033	0.5	0.5
0.0154	0.318	0.3118
0.0028	0.3518	0.3518
0.0215	0.2584	0.2584
0.0003	0.5	0.5
0.0017	1	1
0.0093	0.5	0.5
0.0016	1	1
0.0099	0.7062	0.7062
0.0004	0.5	0.5
0.002	0.2769	0.2789
0.0015	1	1
0.0012	1	1
0.0008	1	1
0.0113	0.3417	0.3417
0.0041	1	1
0.007	1	1
0.0229	0.276	0.276
0.0022	0.3489	0.3489
0.0023	0.2653	0.2653
0.0254	0.2771	0.4558
0.0016	0.2512	0.2512
0.0015	0.5	0.5
0.0015	1	1
0.0012	0.5	0.5
0.002	0.5	0.5
0.0512	0.3839	0.433
0.027	0.2915	0.5193
0.0023	0.2994	0.2994
0.0862	1	1
0.0032	0.5	0.5
0.0019	0.4068	0.4068
0.0164	0.5429	0.5109
0.0019	1	1
0.0019	0.2508	0.2508
0.0049	1	1
0.1271	1	1
0.0467	0.2737	0.3342
0.0074	1	1
0.000376403	0.5	0.5
0.0015	1	1
0.0792	0.2512	0.2511
0.0015	0.5	0.5
0.0111	0.2611	0.4326
0.0018	0.2533	0.2533
0.0021	0.5	0.5
0.0829	0.3096	0.3096
0.0473	0.352	0.3514
0.0016	0.4068	0.4068
0.0062	0.2514	0.2514
0.0019	1	1
0.0835	0.2977	0.2977
0.0032	1	1
0.0019	1	1
0.0019	1	1
0.0019	0.5	0.5
0.0051	0.5	0.5
0.0244	0.3338	0.3338
0.0668	0.2671	0.2671
0.0015	1	1
0.0139	0.2712	0.2712
0.0097	0.4203	0.4203
0.0004	0.5	0.5
0.0052	1	1
0.0095	0.2679	0.3344
0.0027	0.3035	0.3035
0.0019	1	1
0.0062	0.5	0.5
0.0115	1	1
0.0011	0.3523	0.3523
0.0257	0.3027	0.3034
0.0015	1	1
0.0029	0.8403	0.947
0.0357	0.3326	0.3326
0.0077	0.4695	0.4695
0.0027	0.325	0.325
0.0024	1	1
0.0025	1	1
0.0353	1	1
0.0199	0.281	0.3094
0.0031	0.5962	1
0.0019	0.4592	0.4592
0.0023	0.4592	0.4592
0.0374	1	1
0.01	1	1
0.0015	1	1
0.0049	1	1
0.0964	0.2502	0.2498
0.0264	0.2548	0.351
0.0015	1	1
0.0024	1	1
0.0111	0.3689	0.3643
0.0004	1	1
0.0023	0.4592	0.4592
0.0027	0.325	0.325
0.0303	1	1
0.0038	0.8247	0.9192
0.0041	1	1
0.0102	0.253	0.2839
0.0014	1	1
0.0015	1	1
0.0169	1	1
0.025	0.3445	0.3445
0.00208876	1	1
0.0103	0.3896	0.3896
0.0163	0.2612	0.254
0.0004	0.5	0.5
0.0023	0.4592	0.4592
0.0127	0.2572	0.2856
0.0346	1	1
0.0045	0.5744	0.5369
0.0019	0.259	0.2761
0.0207	0.2987	0.2987
0.007	1	1
0.0115	0.5883	0.5682
0.003	0.3514	0.3514
0.0015	1	1
0.0104	0.2521	0.2521
0.0019	1	1
0.0137	0.8582	0.8203
0.036	0.2554	1
0.0015	0.481	0.4046
0.0172	0.3364	0.3364
0.0014	0.481	0.4046
0.0149	0.3673	0.3673
0.0019	0.5471	0.5471
0.0159	0.291	0.2888
0.0023	0.5071	0.5071
0.0004	0.5	0.5
0.0145	0.7126	0.7126
0.0026	1	1
0.0052	0.5	0.5
0.0069	0.5	0.5
0.00209666	0.414266	0.469403
0.0158515	0.318774	0.354398
0.0027	1	1
0.0248	0.2781	0.2874
0.0378	0.2617	0.2598
0.0165	0.6839	1
0.012	0.5441	1
0.0016	0.4068	0.4068
0.0008	0.5	0.5
0.0004	0.5	0.5
0.0029	0.3413	0.3413
0.0015	1	1
0.0028	1	1
0.0044	0.2549	0.2828
0.0004	0.5	0.5
0.0013	1	1
0.0019	0.2508	0.2508
0.0015	1	1
0.0024	1	1
0.0066	0.5	0.5
0.0004	0.5	0.5
0.0076	1	1
0.0016	0.2512	0.2512
0.0019	1	1
0.0015	1	1
0.0008	0.4068	0.4068
0.0011	0.5	0.5
0.0088	1	1
0.0196032	0.340079	0.377299
0.0004	0.5	0.5
0.0016	0.2512	0.2512
0.004	0.6426	0.4276
0.0023	0.2804	0.2804
0.0822	0.2614	0.261
0.0028	0.2724	0.325
0.0039	0.2583	0.2792
0.0027	0.284	0.284
0.0229	0.2844	0.3348
0.0032	0.3757	0.3757
0.0127	0.4462	0.4462
0.0118	0.3724	0.403
0.0012	0.5	0.5
0.0052	1	1
0.0015	0.3523	0.3523
0.0027	0.3491	0.3491
0.0025	1	1
0.0015	1	1
0.0018	1	1
0.0089	0.4844	0.4844
0.0022	0.3789	0.3789
0.0157	0.305	0.3017
0.0014	1	1
0.0119	0.4162	0.4162
0.0066	0.3721	0.4106
0.0015	1	1
0.0051	0.3758	0.4112
0.0018	0.2639	0.2939
0.0044	0.3316	0.3316
0.0013	1	1
0.0112	0.3296	0.3296
0.0225962	1	1
0.0098	0.6442	0.6442
0.0452	0.3611	0.3611
0.0049	0.4269	0.4269
0.0226	0.2761	0.2761
0.0046	1	1
0.0004	0.5	0.5
0.0013	0.5	0.5
0.0053	1	1
0.0033	0.9143	0.9143
0.0013	0.5	0.5
0.0175	0.2516	0.2516
0.0042	0.3082	0.3082
0.0015	1	1
0.0004	0.5	0.5
0.0015	1	1
0.0085	0.4378	0.4378
0.0062	1	1
0.00248392	1	1
0.0019	0.2639	0.2939
0.0046	0.4133	0.4668
0.0052	0.3769	0.4125
0.0019	1	1
0.0097	0.5071	0.5071
0.0177	0.352	1
0.0016	0.2571	0.2571
0.0102	0.526	0.526
0.0177	0.3022	0.4483
0.007	1	1
0.0027	0.3191	0.3046
0.0034	0.4068	0.4068
0.00741961	1	1
0.0025	0.3748	0.3748
0.0145	0.3273	0.3298
0.0464	0.4861	0.4861
0.0327	0.3118	0.3118
0.0026	1	1
0.0262	0.3142	0.7238
0.0015	0.9812	0.9812
0.0074	0.476	0.5279
0.0019	1	1
0.0004	0.5	0.5
0.0073	0.5	0.5
0.0122	0.3409	0.3971
0.0012	0.8287	0.8287
0.0273	0.3136	0.3136
0.0128	0.3345	0.3345
0.0169	0.2899	0.356
0.0066	1	1
0.0019	0.5	0.5
0.0023	0.5	0.5
0.0192	0.3715	0.8674
0.0004	0.5	0.5
0.0207	0.4059	0.4059
0.0011	0.5	0.5
0.0053	1	1
0.0927	1	1
0.0026	1	1
0.0024	1	1
0.0192	0.943	0.943
0.0018	1	1
0.0241	0.2677	0.2677
0.004	0.7415	0.8404
0.0245	0.3462	0.3462
0.0291	0.3014	0.469
0.0045	0.3249	0.3249
0.1011	0.267	0.267
0.0023	0.4592	0.4592
0.011	0.2513	0.2513
0.00104187	0.742903	0.742903
0.0539	0.4651	0.4651
0.0049	0.3402	0.3402
0.0023	0.2765	0.2953
0.0196	0.2792	0.2775
0.0097	0.4346	0.4346
0.0184	0.305	0.305
0.0067	0.2761	0.2716
0.0023	0.2653	0.2653
0.0032	0.3757	0.3757
0.0086	0.3451	0.3767
0.011	0.3428	0.4592
0.0022	1	1
0.0038	0.2653	0.2653
0.0015	0.5	0.5
0.0373	0.5235	0.5235
0.0052	1	1
0.0048	1	1
0.0025	1	1
0.086	0.2922	0.2914
0.0039	1	0.5
0.0193	1	1
0.0019	1	1
0.0015	1	1
0.0113	0.3108	0.3108
0.0222	1	1
0.0004	0.5	0.5
0.00248392	1	1
0.0333	1	1
0.0051	1	1
0.0196032	0.340079	0.377299
0.0091	0.2991	0.2991
0.0237	0.6464	0.9139
0.0004	0.5	0.5
0.0228	0.3183	0.3183
0.0011	0.5	0.5
0.0023	1	1
0.0165	0.3391	0.4527
0.0007	0.5	0.5
0.0004	0.5	0.5
0.0173	0.3875	0.4426
0.0171	0.2651	0.3501
0.0057	0.2766	0.9062
0.0039	0.4995	1
0.0288	0.2613	0.3096
0.0028	0.325	0.325
0.00295136	0.43504	0.43504
0.0312	0.5853	1
0.0004	1	1
0.052	0.2918	0.2918
0.0004	0.5	0.5
0.0019	1	1
0.0277	0.2644	0.2644
0.0661	0.346	0.346
0.0218	1	1
0.0088	0.2906	0.3351
0.0025	0.5	0.5
0.0015	1	1
0.0025	1	1
0.0019	1	1
0.0019	1	1
0.007	0.4378	0.4378
0.0004	0.5	0.5
0.0318	1	1
0.0023	1	1
0.0207	0.3042	0.3042
0.0015	0.5	0.5
0.0209	0.2968	0.2968
0.0004	0.5	0.5
0.0151	0.2643	0.2622
0.1109	0.2517	0.2516
0.0023	0.3746	0.3678
0.0085	1	1
0.0004	0.5	0.5
0.0056	0.4994	0.4994
0.0026	0.2549	0.2549
0.0019	1	1
0.0027	1	1
0.0177	0.3022	0.4483
0.0015	1	1
0.011	0.3296	0.3296
0.0015	1	1
0.001	1	1
0.0013	0.8284	0.8284
0.0023	0.2931	0.2931
0.0237	0.6464	0.9139
0.0816	0.2803	0.2799
0.0232	0.3182	0.3182
0.0077	0.4133	0.4668
0.0004	0.5	0.5
0.0026	0.3143	0.3143
0.0044	0.3388	0.3388
0.0032	0.3757	0.3757
0.0129	0.4592	0.4592
0.0612	0.2868	0.2867
0.0178	0.3765	0.3765
0.0058	0.3748	0.3724
0.0042	1	1
0.0004	0.5	0.5
0.0068	0.3397	0.3397
0.0007	0.5	0.5
0.0207	0.2987	0.2987
0.0012	1	1
0.0022	0.2968	0.2968
0.0068	1	1
0.0244	0.4931	1
0.012	1	1
0.0016	0.259	0.2887
0.0019	0.4068	0.4068
0.0019	0.7046	0.7046
0.0028	0.2506	0.2952
0.003	1	1
0.0027	1	1
0.0004	0.5	0.5
0.0018	0.4068	0.4068
0.0254	0.2755	0.4513
0.0055	0.2976	0.2976
0.0741	0.3882	0.3882
0.0025	0.888	0.8358
0.0004	0.5	0.5
0.0015	1	1
0.0014	0.4565	0.4565
0.0015	1	1
0.0246	0.2675	0.2675
0.0274	0.3935	0.3935
0.0019	1	1
0.0074	0.365	0.365
0.002	0.632	0.632
0.0015	0.3523	0.3523
0.0023	0.9674	0.9674
0.0028	1	1
0.012	1	1
0.0291	0.2774	0.2774
0.0107	1	1
0.0012	0.3544	0.3544
0.0019	0.5	0.5
0.0038	0.4586	0.4573
0.0016	1	1
0.0008	0.3317	0.3317
0.0028	0.5202	0.5202
0.0086	1	1
0.0015	1	1
0.0232	0.2739	0.2739
0.0102	0.424	0.4238
0.0004	0.5	0.5
0.0015	1	1
0.0125	0.2745	0.4591
0.0326	0.3322	0.3307
0.1221	0.29	0.29
0.011	0.4046	0.4046
0.0015	1	1
0.0086	0.5	0.5
0.0189	0.3237	0.3235
0.0019	0.5	0.5
0.0033	0.3046	0.3046
0.0036	0.4592	0.4592
0.0041	1	1
0.0004	0.5	0.5
0.0023	0.2931	0.2931
0.0992	0.2794	0.2794
0.0015	1	1
0.0018	0.7046	0.7046
0.0235	0.3289	0.3289
0.0015	0.5	0.5
0.0146	0.6069	0.6069
0.1401	0.2989	0.2989
0.0113	0.3488	0.4867
0.00124196	1	1
0.0229	0.3219	0.5464
0.087	1	1
0.0015	1	1
0.0958	0.3657	0.3653
0.0154	0.5592	0.5602
0.0235	0.3362	0.336
0.0017	0.4068	0.4068
0.0015	1	1
0.0212	0.3283	0.3283
0.1185	1	1
0.0171	0.4997	0.4997
0.008	1	1
0.0018	1	1
0.0036	0.3206	0.3206
0.0026	0.5	0.5
0.0004	0.5	0.5
0.0015	1	1
0.0004	0.5	0.5
0.009	0.5245	0.5245
0.0085	0.3314	0.3314
0.0254	0.2771	0.4558
0.0033	0.2605	0.2605
0.0086	1	1
0.0004	0.5	0.5
0.0142	0.413	0.6051
0.0233	0.3231	0.3231
0.0196	0.2792	0.2775
0.0024	0.4133	0.4668
0.0044	0.3331	0.3331
0.0015	1	1
0.0053	1	1
0.0068	0.4913	0.4913
0.0067	0.5	0.5
0.0019	1	1
0.004	1	1
0.0019	1	1
0.0025	1	1
0.002	1	1
0.0028	0.5	0.5
0.0113	0.3108	0.3108
0.0012	1	1
0.008	1	1
0.0015	1	1
0.1259	1	1
0.014	0.4739	0.4739
0.0113	0.588	0.588
0.0114	0.2592	0.3786
0.0101	0.3057	0.3057
0.0059	0.6064	0.6758
0.0004	0.5	0.5
0.0037	0.2519	0.2808
0.0281	0.3335	0.3335
0.0003	0.5	0.5
0.0016	1	1
0.0019	1	1
0.0166	1	1
0.0095	1	1
0.0047	0.3975	0.3975
0.0014	1	1
0.0013	0.4623	0.4623
0.0052	0.5	0.5
0.0029	0.2663	0.2663
0.0038	1	1
0.0014	1	1
0.0027	1	1
0.0027	0.5	0.5
0.0082	0.5	0.5
0.023	0.3308	0.3308
0.0027	1	1
0.0019	0.259	0.2887
0.0129	0.6175	0.6168
0.0079	0.5905	0.5905
0.0004	0.5	0.5
0.0004	0.5	0.5
0.0019	1	1
0.0042	1	1
0.004	1	1
0.0119	1	1
0.0179	0.6902	1
0.0254	0.2771	0.4558
0.0067	0.5	0.5
0.0093	1	1
0.0027	0.2588	0.554
0.0016	0.2512	0.2512
0.0473	0.352	0.3514
0.0034	0.3593	0.3593
0.0101	0.5653	0.5256
0.003	1	1
0.0124	0.4691	0.4691
0.0166	1	1
0.0092	1	1
0.0085	0.8573	0.8573
0.0019	1	1
0.0053	1	1
0.0053	1	1
0.0019	0.4068	0.4068
0.0023	1	1
0.0031	0.7366	0.7366
0.0012	0.5	0.5
0.0028	0.2572	0.325
0.0139	0.2712	0.2712
0.0065	1	1
0.0015	1	1
0.0163	0.8855	0.883
0.0155	0.9995	0.9995
0.0612	0.2868	0.2867
0.0056	0.3577	0.3577
0.0071	0.3514	0.3514
0.0019	0.257	0.5495
0.0518	0.396	0.396
0.0241	0.2521	0.413
0.0025	1	1
0.0225	0.2738	0.2738
0.0032	0.3757	0.3757
0.0609	0.2839	0.2839
0.007	0.5	0.5
0.008	0.5887	0.5887
0.0224	0.2815	0.2815
0.0015	1	1
0.0036	1	1
0.0026	1	1
0.0012	0.8284	0.8284
0.0372	0.467	0.4662
0.0065	1	1
0.0122	0.2591	0.2562
0.0028	0.2943	0.2943
0.000406623	0.903603	0.903603
0.00248392	1	1
0.0016	0.259	0.2887
0.0023	0.2931	0.2931
0.0089	0.4254	0.5837
0.0092	0.2723	0.3149
0.0059	0.5	0.5
0.0118	0.4854	0.4854
0.0004	0.5	0.5
0.022	0.3653	0.3905
0.0015	1	1
0.0027	0.325	0.325
0.0015	0.3523	0.3523
0.0174	0.3297	0.3297
0.0019	1	1
0.0036	0.5913	0.5788
0.107	0.2588	0.2585
0.0064	0.4681	0.4681
0.0019	1	1
0.0037	0.2677	0.2677
0.0004	0.5	0.5
0.006	1	1
0.0015	1	1
0.0028	0.2591	0.325
0.0019	1	1
0.0128	1	1
0.0054	1	1
0.0004	0.5	0.5
0.0037	0.3013	0.3013
0.0053	1	1
0.0085	1	1
0.0015	0.481	0.4046
0.0037	0.4283	0.4283
0.0086	1	1
0.0077	0.2588	0.2588
0.0377	0.3643	0.3643
0.0074	1	1
0.0291	1	1
0.0004	0.5	0.5
0.0004	0.5	0.5
0.0154	0.2803	0.2803
0.00104187	0.742903	0.742903
0.0265	1	1
0.0019	1	1
0.0077	1	1
0.0074	0.365	0.365
0.0107	1	1
0.0023	0.2653	0.2653
0.0043	0.3077	0.3077
0.0111	0.3572	0.3572
0.0015	0.5	0.5
0.0004	1	1
0.00248392	1	1
0.035	0.3963	0.4089
0.0078	1	1
0.0083	1	1
0.0099	0.3048	0.3393
0.00650957	1	1