Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.0138 | 1 | 1 |
Onchocerca volvulus | Matrilysin homolog | 0.0047 | 0.1561 | 1 |
Brugia malayi | Choline/ethanolamine kinase family protein | 0.0123 | 0.8627 | 0.8627 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 1 | 1 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0047 | 0.1561 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0138 | 1 | 1 |
Loa Loa (eye worm) | matrixin family protein | 0.0051 | 0.1951 | 0.0462 |
Brugia malayi | Matrixin family protein | 0.0051 | 0.1951 | 0.1951 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0138 | 1 | 1 |
Plasmodium falciparum | choline kinase | 0.0123 | 0.8627 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0138 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0138 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0138 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0138 | 1 | 1 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.005 | 0.1867 | 0.1867 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0138 | 1 | 1 |
Plasmodium vivax | choline kinase, putative | 0.0123 | 0.8627 | 0.5 |
Echinococcus granulosus | choline:ethanolamine kinase | 0.0123 | 0.8627 | 0.758 |
Loa Loa (eye worm) | choline/ethanolamine kinase | 0.0123 | 0.8627 | 0.8373 |
Toxoplasma gondii | phosphotransferase enzyme family protein | 0.0123 | 0.8627 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0138 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0138 | 1 | 1 |
Echinococcus multilocularis | choline:ethanolamine kinase | 0.0123 | 0.8627 | 0.758 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.