Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0662 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1284 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.1284 | 0.1284 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0106 | 1 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.1284 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1284 | 0.5 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0662 | 0.5 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0662 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1284 | 0.5 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0106 | 1 | 1 |
Echinococcus multilocularis | segment polarity protein dishevelled | 0.0106 | 1 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.1284 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1284 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1284 | 1 |
Echinococcus granulosus | segment polarity protein dishevelled | 0.0106 | 1 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0662 | 0.139 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.1284 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.1284 | 0.1284 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.1284 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1284 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1284 | 0.1284 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0662 | 0.0662 |
Onchocerca volvulus | Segment polarity protein dishevelled homolog | 0.0061 | 0.5211 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0662 | 0.0662 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1284 | 0.1284 |
Toxoplasma gondii | hypothetical protein | 0.0011 | 0 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.1284 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.1284 | 1 |
Brugia malayi | DIX domain containing protein | 0.0021 | 0.1015 | 0.1015 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0662 | 0.0662 |
Loa Loa (eye worm) | DIX domain-containing protein | 0.0021 | 0.1015 | 0.1015 |
Schistosoma mansoni | dishevelled | 0.0106 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1284 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1284 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0662 | 0.0662 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0662 | 0.0662 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.1284 | 0.1284 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1284 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.1284 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1284 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1284 | 0.1284 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.1284 | 1 |
Schistosoma mansoni | dishevelled | 0.0095 | 0.8825 | 0.8825 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.