Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 8 ug ml-1 | In Vitro antimicrobial activity against Mycobacterium avium complex (MAC) strain ATCC 15769 | ChEMBL. | 10649975 |
MIC (functional) | = 8 ug ml-1 | In Vitro antimicrobial activity against Mycobacterium tuberculosis (MT) Wild type strain MT-1 | ChEMBL. | 10649975 |
MIC (functional) | = 8 ug ml-1 | In Vitro antimicrobial activity against Mycobacterium tuberculosis (MT) Wild type strain MT-2 | ChEMBL. | 10649975 |
MIC (functional) | = 16 ug ml-1 | In Vitro antimicrobial activity against Mycobacterium tuberculosis (MT) strain H-37-Rv ATCC | ChEMBL. | 10649975 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.