Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.004 | 0.1191 | 0.1191 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7053 | 0.7053 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0059 | 0.2218 | 0.3144 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0548 | 0.5 |
Echinococcus multilocularis | geminin | 0.02 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0455 | 0.0645 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.008 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7053 | 0.7053 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.0455 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0146 | 0.7053 | 0.7053 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.0455 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7053 | 0.7053 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0548 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0146 | 0.7053 | 1 |
Schistosoma mansoni | hypothetical protein | 0.02 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.02 | 1 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.0455 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0548 | 0.0777 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.0455 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0455 | 0.0645 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.008 | 0.0114 |
Brugia malayi | RNA binding protein | 0.0146 | 0.7053 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0455 | 0.0645 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7053 | 0.7053 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0548 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0146 | 0.7053 | 1 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0548 | 0.0777 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0455 | 0.0645 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1191 | 0.1689 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0455 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0146 | 0.7053 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0455 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.008 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.008 | 0.0114 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0027 | 0.0455 | 0.5 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0455 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0548 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0455 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0059 | 0.2218 | 0.3144 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0455 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0146 | 0.7053 | 0.7053 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0548 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.2218 | 0.3144 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.0455 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0455 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.008 | 0.139 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.1191 | 0.1689 |
Onchocerca volvulus | 0.0027 | 0.0455 | 0.5 | |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.0455 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0548 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0455 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.008 | 0.0114 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0548 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0455 | 0.0645 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0146 | 0.7053 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.008 | 0.0114 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0455 | 0.0645 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0059 | 0.2218 | 0.3144 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0455 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0146 | 0.7053 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0146 | 0.7053 | 0.7053 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0548 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.