Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0072 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0126 | 0.3019 | 0.0555 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3019 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.2608 | 0.2608 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0126 | 0.3019 | 0.3019 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3019 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0126 | 0.3019 | 0.0555 |
Echinococcus multilocularis | tar DNA binding protein | 0.0126 | 0.3019 | 0.3019 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0253 | 1 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0253 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0126 | 0.3019 | 0.0555 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3019 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0126 | 0.3019 | 0.3019 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0126 | 0.3019 | 0.3019 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3019 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0 | 0.5 |
Brugia malayi | RNA binding protein | 0.0126 | 0.3019 | 0.3019 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3019 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.