Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.9472 | 0.9472 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0035 | 0.7865 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.9472 | 0.9472 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.9472 | 0.9472 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.9472 | 0.9472 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.9472 | 0.9472 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.9472 | 0.9472 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.9472 | 0.9472 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0035 | 0.7865 | 1 |
Brugia malayi | hypothetical protein | 0.0038 | 0.9472 | 0.9472 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.9472 | 0.9472 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | Inhibition of mouse recombinant serine racemase expressed in Escherichia coli MC1061 assessed as formation of D-serine at 5 mM after 30 mins by HPLC analysis | ChEMBL. | 19791805 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.