Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | jmjC domain containing protein | 0.0063 | 0.1306 | 0.113 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.004 | 0.0199 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0063 | 0.1306 | 0.1864 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2804 | 0.2658 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0063 | 0.1306 | 0.1864 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6138 | 1 |
Brugia malayi | hypothetical protein | 0.0095 | 0.2804 | 0.2658 |
Schistosoma mansoni | eyes absent homolog | 0.0095 | 0.2804 | 0.4387 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6138 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0199 | 0.5 |
Echinococcus granulosus | geminin | 0.0165 | 0.6138 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.004 | 0.0199 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0199 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0199 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0246 | 1 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.1306 | 0.113 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0199 | 0.5 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0063 | 0.1306 | 0.1864 |
Echinococcus multilocularis | geminin | 0.0165 | 0.6138 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0063 | 0.1306 | 0.1864 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0063 | 0.1306 | 0.1864 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0199 | 0.5 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.004 | 0.0199 | 0.5 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.004 | 0.0199 | 0.5 |
Schistosoma mansoni | jumonji domain containing protein | 0.0063 | 0.1306 | 0.1864 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.004 | 0.0199 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0063 | 0.1306 | 0.1864 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0036 | 0 | 0.5 |
Brugia malayi | jmjC domain containing protein | 0.0063 | 0.1306 | 0.113 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2804 | 0.2658 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0199 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.