Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | RNA binding protein | 0.0068 | 0.4661 | 0.4661 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4661 | 0.6916 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4661 | 0.6916 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.2441 | 0.5237 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4661 | 0.6916 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.4661 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0642 | 0.5 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0102 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.0642 | 0.0952 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0642 | 0.0642 |
Schistosoma mansoni | jumonji domain containing protein | 0.0081 | 0.674 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0642 | 0.5 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0102 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4661 | 0.6916 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.4661 | 0.4661 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0878 | 0.0878 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.4661 | 0.4661 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.4661 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0068 | 0.4661 | 0.6916 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.0642 | 0.0642 |
Echinococcus multilocularis | tar DNA binding protein | 0.0068 | 0.4661 | 0.4661 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0642 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0068 | 0.4661 | 0.4661 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0642 | 0.0952 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.4661 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0642 | 0.5 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0064 | 0.4138 | 0.8878 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.0642 | 0.0642 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0878 | 0.0878 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.