Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0067 | 0.9049 | 0.5 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0067 | 0.9049 | 0.9049 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.9049 | 0.9049 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.9049 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0054 | 0.4989 | 0.4989 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.9049 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 1 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0067 | 0.9049 | 0.9049 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.007 | 1 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0067 | 0.9049 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0054 | 0.4989 | 0.4989 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 1 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0067 | 0.9049 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0067 | 0.9049 | 0.9049 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0067 | 0.9049 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 3.9 uM | Evaluated for the antioxidant property by measuring the inhibition of microsomal lipid peroxidation | ChEMBL. | 11206462 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.