Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | inhibitor of apoptosis protein | 0.0444 | 0.4727 | 1 |
Giardia lamblia | DNA repair protein RAD52 | 0.0344 | 0.3361 | 0.5 |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.0444 | 0.4727 | 1 |
Schistosoma mansoni | inhibitor of apoptosis protein | 0.0444 | 0.4727 | 0.5 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.0444 | 0.4727 | 0.2026 |
Entamoeba histolytica | DNA repair and recombination protein RAD52, putative | 0.0344 | 0.3361 | 1 |
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.0444 | 0.4727 | 0.2026 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0444 | 0.4727 | 0.5 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0444 | 0.4727 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0444 | 0.4727 | 0.5 |
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.0444 | 0.4727 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0444 | 0.4727 | 0.5 |
Onchocerca volvulus | 0.0444 | 0.4727 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0444 | 0.4727 | 0.5 |
Onchocerca volvulus | Deterin homolog | 0.0444 | 0.4727 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.