Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0159 | 0.1065 | 0.224 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0082 | 0.0106 | 0.0106 |
Echinococcus granulosus | voltage dependent calcium channel subunit | 0.0362 | 0.3578 | 0.8107 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0082 | 0.0106 | 0.0054 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0159 | 0.1065 | 0.224 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1065 | 0.1065 |
Echinococcus multilocularis | geminin | 0.0355 | 0.3481 | 0.7882 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0159 | 0.1065 | 0.1065 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0159 | 0.1065 | 0.224 |
Schistosoma mansoni | hypothetical protein | 0.0355 | 0.3481 | 0.7894 |
Echinococcus granulosus | voltage dependent calcium channel subunit | 0.0165 | 0.1135 | 0.2403 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0159 | 0.1065 | 0.224 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0106 | 0.0106 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0159 | 0.1065 | 0.224 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0159 | 0.1065 | 0.2282 |
Schistosoma mansoni | high voltage-activated calcium channel beta subunit 2 | 0.0428 | 0.4388 | 1 |
Echinococcus multilocularis | voltage dependent calcium channel subunit | 0.0362 | 0.3578 | 0.8107 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0159 | 0.1065 | 0.224 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0159 | 0.1065 | 0.224 |
Echinococcus granulosus | high voltage activated calcium channel beta | 0.0428 | 0.4388 | 1 |
Onchocerca volvulus | 0.0082 | 0.0106 | 0.5 | |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0159 | 0.1065 | 0.224 |
Echinococcus multilocularis | high voltage activated calcium channel beta | 0.0428 | 0.4388 | 1 |
Loa Loa (eye worm) | calcium channel | 0.0159 | 0.1065 | 0.1065 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0159 | 0.1065 | 0.224 |
Schistosoma mansoni | dihydropyridine-sensitive l-type calcium channel | 0.0158 | 0.1052 | 0.2251 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0159 | 0.1065 | 0.224 |
Loa Loa (eye worm) | voltage-dependent calcium channel beta 2a subunit | 0.0882 | 1 | 1 |
Echinococcus multilocularis | voltage dependent calcium channel subunit | 0.0165 | 0.1135 | 0.2403 |
Echinococcus granulosus | geminin | 0.0355 | 0.3481 | 0.7882 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0159 | 0.1065 | 0.2282 |
Schistosoma mansoni | serine-rich repeat protein | 0.0085 | 0.015 | 0.0156 |
Schistosoma mansoni | hypothetical protein | 0.0355 | 0.3481 | 0.7894 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.015 | 0.0156 |
Schistosoma mansoni | voltage-gated cation channel | 0.0159 | 0.1065 | 0.2282 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.